Patents by Inventor Brian Henry Vickery

Brian Henry Vickery has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fracture healing using pthrp analogs
    Patent number: 6583114
    Abstract: This invention provides methods of bone healing and fracture repair comprising administering to a patient in need thereof an effective amount of a polypeptide analog of parathyroid hormone related peptide (PTHrP) and salts thereof, wherein amino acid residues 22-31 form an amphipathic &agr;-helix. Systemic administration is a preferred mode of delivery.
    Type: Grant
    Filed: September 3, 1998
    Date of Patent: June 24, 2003
    Assignee: Roche Palo Alto LLC
    Inventor: Brian Henry Vickery
  • FRACTURE HEALING USING PTHRP ANALOGS
    Publication number: 20020077281
    Abstract: This invention provides methods of bone healing and fracture repair comprising administering to a patient in need thereof an effective amount of a polypeptide analog of parathyroid hormone related peptide (PTHrP) and salts thereof, wherein amino acid residues 22-31 form an amphipathic &agr;-helix. Systemic administration is a preferred mode of delivery.
    Type: Application
    Filed: September 3, 1998
    Publication date: June 20, 2002
    Inventor: BRIAN HENRY VICKERY
  • Pharmaceutical compositions for the nasal delivery of compounds useful for the treatment of osteoporosis
    Patent number: 5977070
    Abstract: A pharmaceutical composition for the nasal delivery of compounds useful for treating osteoporosis, comprising an effective amount of a physiologically active truncated analog of PTH or PTHrp, or salt thereof, in which amino acid residues (22-31) form an amphipathic .alpha.-helix, said residues (22-31) selected from (SEQ ID NOS: 85, 86, 26, 27, 28, 29, and 30); an absorption enhancer selected from the group consisting of dimethyl-.beta.-cyclodextrin and the bile acid surfactants; and water is provided.
    Type: Grant
    Filed: August 29, 1995
    Date of Patent: November 2, 1999
    Inventors: Christin Teresa Piazza, Michael Lloyd Radomsky, John Leonard Krstenansky, John Joseph Nestor, Jr., Brian Henry Vickery
  • Method for treating osteoporosis
    Patent number: 5696103
    Abstract: A method for treating osteoporosis via administration of a compound of the formula, 1.alpha.-fluoro-25-hydroxy-16-ene-23-yne-26,27-hexafluorocholecalciferol, in an amount therapeutically effective to restore bone density to an asymptomatic level, without inducing hypercalciuria, hypercalcemia, or nephrotoxicity is provided.
    Type: Grant
    Filed: November 17, 1995
    Date of Patent: December 9, 1997
    Assignees: Syntex (U.S.A.) Inc., Hoffmann-La Roche Inc.
    Inventors: John Joseph Nestor, Jr., Brian Henry Vickery, Milan Radoje Uskokovic