Patents by Inventor Brian Holloway
Brian Holloway has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240122080Abstract: A superconductor device includes a high superconductivity transition temperature enhanced from the raw material transition temperature. The superconductor device includes a matrix material and a core material. The enhancing matrix material and the core material together create a system of strongly coupled carriers. A plurality of low-dimensional conductive features can be embedded in the matrix. The low-dimensional conductive features (e.g., nanowires or nanoparticles) can be conductors or superconductors. An interaction between electrons of the low-dimensional conductive features and the enhancing matrix material can promote excitations that increase a superconductivity transition temperature of the superconductor device.Type: ApplicationFiled: October 9, 2023Publication date: April 11, 2024Inventors: Philipp Braeuninger-Weimer, Nathan P. Myhrvold, Conor L. Myhrvold, Cameron Myhrvold, Clarence T. Tegreene, Roderick A. Hyde, Lowell L. Wood, JR., Muriel Y. Ishikawa, Victoria Y.H. Wood, David R. Smith, John Brian Pendry, Charles Whitmer, William Henry Mangione-Smith, Brian C. Holloway, Stuart A. Wolf, Vladimir Z. Kresin
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Publication number: 20240108236Abstract: Hemodynamic monitoring system is presented. In one embodiment, a system for non-invasive monitoring of a subject's heart includes an RF transmitting antenna. The RF transmitting antenna is configured for transmitting at least one transmitted RF signal toward the subject. The system also includes an RF receiving antenna. The RF receiving antenna is configured for receiving at least one received RF signal transmitted by the RF transmitting antenna and modified by a subject's body. The RF transmitting antenna and the RF receiving antenna are located on opposing sides of a planar projection of the subject's heart. The system also includes a processing circuit configured for: controlling transmitting and receiving of the RF signal, and determining, based on the at least one received RF signal, at least one physiological parameter of the subject.Type: ApplicationFiled: September 21, 2023Publication date: April 4, 2024Applicant: DEEP SCIENCE, LLCInventors: David Nelson Coar, Tony Falcone, Brian Holloway, Michael Madden, Jay William McDaniel
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Patent number: 11933334Abstract: Systems and methods are described herein to implement transverse momentum injection at low frequencies to directly modify large-scale eddies in a turbulent boundary layer on a surface of an object. A set of transverse momentum injection actuators may be positioned on the surface of the object to affect large-scale eddies in the turbulent boundary layer. The system may include a controller to selectively actuate the transverse momentum injection actuators with an actuation pattern to affect the large-scale eddies to modify the drag, fluid mixing, heat transfer, and/or other interactions of the fluid flow with the surface. In various embodiments, the transverse momentum injection actuators may be operated at frequencies less than 10,000 Hertz.Type: GrantFiled: May 18, 2023Date of Patent: March 19, 2024Assignee: Enterprise Science Fund, LLCInventors: Alexander J. Smits, Ivan Marusic, David Wine, Brian Holloway
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Publication number: 20230304516Abstract: Systems and methods are described herein to implement transverse momentum injection at low frequencies to directly modify large-scale eddies in a turbulent boundary layer on a surface of an object. A set of transverse momentum injection actuators may be positioned on the surface of the object to affect large-scale eddies in the turbulent boundary layer. The system may include a controller to selectively actuate the transverse momentum injection actuators with an actuation pattern to affect the large-scale eddies to modify the drag, fluid mixing, heat transfer, and/or other interactions of the fluid flow with the surface. In various embodiments, the transverse momentum injection actuators may be operated at frequencies less than 10,000 Hertz.Type: ApplicationFiled: May 18, 2023Publication date: September 28, 2023Inventors: Alexander J. Smits, Ivan Marusic, David Wine, Brian Holloway
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Patent number: 11692566Abstract: Systems and methods are described herein to implement transverse momentum injection at low frequencies to directly modify large-scale eddies in a turbulent boundary layer on a surface of an object. A set of transverse momentum injection actuators may be positioned on the surface of the object to affect large-scale eddies in the turbulent boundary layer. The system may include a controller to selectively actuate the transverse momentum injection actuators with an actuation pattern to affect the large-scale eddies to modify the drag of the fluid flow on the surface. In various embodiments, the transverse momentum injection actuators may be operated at frequencies less than 10,000 Hertz.Type: GrantFiled: October 6, 2022Date of Patent: July 4, 2023Inventors: Alexander J. Smits, Ivan Marusic, David Wine, Brian Holloway
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Publication number: 20230044837Abstract: Systems and methods are described herein to implement transverse momentum injection at low frequencies to directly modify large-scale eddies in a turbulent boundary layer on a surface of an object. A set of transverse momentum injection actuators may be positioned on the surface of the object to affect large-scale eddies in the turbulent boundary layer. The system may include a controller to selectively actuate the transverse momentum injection actuators with an actuation pattern to affect the large-scale eddies to modify the drag of the fluid flow on the surface. In various embodiments, the transverse momentum injection actuators may be operated at frequencies less than 10,000 Hertz.Type: ApplicationFiled: October 6, 2022Publication date: February 9, 2023Inventors: Alexander J. Smits, Ivan Marusic, David Wine, Brian Holloway
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Patent number: 11466709Abstract: Systems and methods are described herein to implement transverse momentum injection at low frequencies to directly modify large-scale eddies in a turbulent boundary layer on a surface of an object. A set of transverse momentum injection actuators may be positioned on the surface of the object to affect large-scale eddies in the turbulent boundary layer. The system may include a controller to selectively actuate the transverse momentum injection actuators with an actuation pattern to affect the large-scale eddies to modify the drag of the fluid flow on the surface. In various embodiments, the transverse momentum injection actuators may be operated at frequencies less than 10,000 Hertz.Type: GrantFiled: February 16, 2022Date of Patent: October 11, 2022Assignee: Deep Science, LLCInventors: Alexander J. Smits, Ivan Marusic, David Wine, Brian Holloway
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Publication number: 20220260098Abstract: Systems and methods are described herein to implement transverse momentum injection at low frequencies to directly modify large-scale eddies in a turbulent boundary layer on a surface of an object. A set of transverse momentum injection actuators may be positioned on the surface of the object to affect large-scale eddies in the turbulent boundary layer. The system may include a controller to selectively actuate the transverse momentum injection actuators with an actuation pattern to affect the large-scale eddies to modify the drag of the fluid flow on the surface. In various embodiments, the transverse momentum injection actuators may be operated at frequencies less than 10,000 Hertz.Type: ApplicationFiled: February 16, 2022Publication date: August 18, 2022Inventors: Alexander J. Smits, Ivan Marusic, David Wine, Brian Holloway
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Patent number: 8119788Abstract: Compositions and methods for detecting and/or differentiating among Candida organisms, including C. albicans and C. dubliniensis, are disclosed. Exemplary methods involve screening a sample suspected of containing at least one or more Candida sp. for the presence or absence of a nucleic acid sequence specific for each such fungal pathogen. Some disclosed methods permit the rapid and simultaneous detection and identification of several fungal pathogens (e.g., up to 100 fungi) in a single sample.Type: GrantFiled: September 26, 2006Date of Patent: February 21, 2012Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and PreventionInventors: Christine J. Morrison, Sanchita Das, Teresa Brown, Brian Holloway
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Publication number: 20110062390Abstract: A functionalized trimetallic nitride endohedral fullerene based material can be represented according to the formula: A3-nXnN@Cm (R)o, wherein: where A and X are one or a combination of the following metal atoms: Sc, Y, La, Ce, Pr, Nd, Gd, Tb, Dy, Ho, Er, Tm, Lu; (n=0-3); N is nitrogen; Cm is a fullerene and m=about 60-about 200; and R is an organic, inorganic, or organometallic species. Related compositions, devices and methods are also described.Type: ApplicationFiled: November 17, 2008Publication date: March 17, 2011Applicant: LUNA INNOVATIONS INCORPORATEDInventors: Claudia Maria Cardona, Martin Drees, Brian Holloway
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Publication number: 20110020804Abstract: This application provides photoinduced electron transfer (PET) nucleic acid molecules that can be used detect and amplify nucleic acid molecules, such as target nucleic acid molecules. These PET tags can be attached to the 5?-end of a target sequence-specific primer, thereby generating a PET primer. In particular examples, a PET tag includes a 5?-labeled nucleotide that can be quenched by at least two consecutive Gs within the tag sequence, and is unquenched when the PET tag hybridizes with its complementary nucleic acid molecule. Also disclosed are methods of using PET primers in nucleic acid amplification, such as real-time PCR.Type: ApplicationFiled: November 21, 2008Publication date: January 27, 2011Inventors: Jothikumar Narayanan, Vincent Hill, Brian Holloway
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Publication number: 20080248970Abstract: Compositions and methods for detecting and/or differentiating among Candida organisms, including C. albicans and C. dubliniensis, are disclosed. Exemplary methods involve screening a sample suspected of containing at least one or more Candida sp. for the presence or absence of a nucleic acid sequence specific for each such fungal pathogen. Some disclosed methods permit the rapid and simultaneous detection and identification of several fungal pathogens (e.g., up to 100 fungi) in a single sample.Type: ApplicationFiled: September 26, 2006Publication date: October 9, 2008Inventors: Christine J. Morrison, Sanchita Das, Teresa Brown, Brian Holloway
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Publication number: 20060213899Abstract: Current industrial and research applications that utilize resistance heating and temperature measurement require separate power and temperature connections, typically two for each. Such applications require separate assemblies and control. We describe herein a combined unit utilizing a thermocouple wire as one of its two leads. The resulting device requires only two connections and one control. An alternating cycle can be used to apply heating power, and temperature measurements are made during the power off portion of the cycle.Type: ApplicationFiled: November 29, 2005Publication date: September 28, 2006Inventors: Ronald Outlaw, Brian Holloway
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Patent number: 6235890Abstract: The present invention provides a rapid method for identifying species of Candida. Identification is through the use of a non-conserved regions of the ITS2 region flanked by highly conserved functional domains. Detection of members of the Candida and Aspergillus genera is enhanced by the detection of genus-specific regions of the 5.8S rRNA gene. The present invention provides isolated nucleic acids that selectively hybridize to the fungal genus-specific 5.8S rRNA region, and to the species-specific ITS2 region. The invention provides for nucleic acid sequences for use as selective probes for fungal genus-specific probes and as Candida species-specific probes. The present invention provides methods for the use of the Candida species-specific probes that allow the detection and identification of the individual species in biological samples.Type: GrantFiled: July 12, 1999Date of Patent: May 22, 2001Assignee: The United States of America as represented by the Department of Health and Human ServicesInventors: Christine J. Morrison, Errol Reiss, Brian Holloway, Jong Hee Shin