Patents by Inventor Brian Issell

Brian Issell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Composition of immunotoxins with interleukin-2
    Patent number: 4894227
    Abstract: Anti-tumor activity in humans can be augmented by administering to the mammalian host a pharmacologically effective amount of mammalian IL-2 and at least one immunotoxin that binds selectively to human tumor cells. The IL-2 and immunotoxin are preferably administered separately to the host. The composition is useful for prophylactic or therapeutic treatment of such cancers as ovarian and breast cancer.
    Type: Grant
    Filed: May 29, 1987
    Date of Patent: January 16, 1990
    Assignee: Cetus Corporation
    Inventors: Paul Stevens, L. L. Houston, Kirston E. Koths, Brian Issell
  • Combination therapy using immunotoxins with interleukin-2
    Patent number: 4863726
    Abstract: Anti-tumor activity in humans can be augmented by administering to the mammalian host a pharmacologically effective amount of mammalian IL-2 and at least one immunotoxin that binds selectively to human tumor cells. The IL-2 and immunotoxin are preferably administered separately to the host. The composition is useful for prophylactic or therapeutic treatment of such cancers as ovarian and breast cancer.
    Type: Grant
    Filed: December 9, 1987
    Date of Patent: September 5, 1989
    Assignee: Cetus Corporation
    Inventors: Paul Stevens, L. L. Houston, Kirston E. Koths, Brian Issell, Robert Zimmerman