Patents by Inventor Brian J. Cox

Brian J. Cox has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220117607
    Abstract: Methods of implanting a device in the lumen of a blood vessel are described. The method includes providing a microcatheter and a device. The device includes a first hub, a second hub, a support structure including a plurality of struts disposed between the first hub and the second hub, and a layer of material disposed over the plurality of struts. The support structure has a low profile, radially constrained state with an elongated tubular configuration suitable for delivery from a microcatheter. The support structure also has an expanded state, a smooth outer surface, and has an axially shortened configuration relative to the radially constrained state. The microcatheter is advanced to a region of interest within the blood vessel. The support structure is advanced through the lumen of and out the distal end of the microcatheter where it expands to the expanded state.
    Type: Application
    Filed: November 4, 2021
    Publication date: April 21, 2022
    Inventors: Brian J. Cox, Dean Schaefer, Robert F. Rosenbluth
  • Patent number: 11304701
    Abstract: A vascular occlusion device includes a braided filament mesh structure defining a longitudinal axis. The mesh structure has a relaxed configuration in which it has an axial array of radially-extending occlusion regions, each of which has a proximal side and a distal side meeting at a peripheral edge, the sides of each occlusion region forming a first angle relative to the longitudinal axis. Each occlusion region is axially separated from the adjacent occlusion region by a reduced-diameter connecting region. The mesh structure is radially compressible to a compressed state in which it is deployed intravascularly to a target site through a catheter. Upon deployment, the device radially expands to a constrained configuration in which the peripheral edges of the occlusion regions engage the vascular wall, and the sides of the occlusion regions form a second angle relative to the longitudinal axis that is smaller than the first angle.
    Type: Grant
    Filed: April 29, 2020
    Date of Patent: April 19, 2022
    Assignee: Inceptus Medical, LLC
    Inventors: Paul Lubock, Richard Quick, Robert Rosenbluth, Brian J. Cox
  • Patent number: 11298137
    Abstract: In a system and method for deployment of an implant device, the implant device includes a first loop at its proximal end, and a deployment tool has a second loop attached at its distal end. A release wire slidably disposed within the deployment tool has a distal end extending through the first and second loops to releasably couple the implant device to the deployment tool, and a proximal portion extending from a proximal end of the deployment tool, which is held in a retraction device. The retraction device is operable to hold the proximal end of the deployment tool and to pull the release wire proximally through the deployment tool until the distal end of the release wire is withdrawn from the first and second loops to decouple the implant device from the deployment tool.
    Type: Grant
    Filed: January 10, 2020
    Date of Patent: April 12, 2022
    Assignee: INCEPTUS MEDICAL LLC
    Inventors: Martin Shabaz, Claudio Plaza, Richard Quick, Paul Lubock, Brian J. Cox
  • Publication number: 20220031335
    Abstract: A vascular occlusion device includes a braided filament mesh structure defining a longitudinal axis. The mesh structure has a relaxed configuration in which it has an axial array of radially-extending occlusion regions, each of which has a proximal side and a distal side meeting at a peripheral edge, the sides of each occlusion region forming a first angle relative to the longitudinal axis. Each occlusion region is axially separated from the adjacent occlusion region by a reduced-diameter connecting region. The mesh structure is radially compressible to a compressed state in which it is deployed intravascularly to a target site through a catheter. Upon deployment, the device radially expands to a constrained configuration in which the peripheral edges of the occlusion regions engage the vascular wall, and the sides of the occlusion regions form a second angle relative to the longitudinal axis that is smaller than the first angle.
    Type: Application
    Filed: October 13, 2021
    Publication date: February 3, 2022
    Inventors: Paul Lubock, Richard Quick, Robert Rosenbluth, Brian J. Cox
  • Publication number: 20220022898
    Abstract: A device and method for intravascular treatment of an embolism, and particularly a pulmonary embolism, is disclosed herein. One aspect of the present technology, for example, is directed toward a clot treatment device that includes a support member having a plurality of first clot engagement members and second clot engagement members positioned about the circumference of a distal portion of the support member. In an undeployed state, individual first clot engagement members can be linear and have a first length, and individual second clot engagement members can be linear and have a second length that is less than the first length. The clot engagement members can be configured to penetrate clot material along an arcuate path and hold clot material to the clot treatment device.
    Type: Application
    Filed: June 24, 2021
    Publication date: January 27, 2022
    Inventors: Brian J. Cox, Paul Lubock, Robert Rosenbluth, Richard Quick, Philippe Marchand
  • Publication number: 20220015798
    Abstract: Systems and methods for removal of thrombus from a blood vessel in a body of a patient are disclosed herein. The method can include: providing a thrombus extraction device including a proximal self-expanding member formed of a unitary fenestrated structure, a distal substantially cylindrical portion formed of a net-like filament mesh structure, and an inner shaft member connected to a distal end of the net-like filament mesh structure; advancing a catheter constraining the thrombus extraction device through a vascular thrombus, deploying the thrombus extraction; retracting the thrombus extraction device to separate a portion of the thrombus from the vessel wall and to capture the portion of the thrombus within the net-like filament mesh structure; and withdrawing the thrombus extraction device from the body to remove thrombus from the patient.
    Type: Application
    Filed: June 29, 2021
    Publication date: January 20, 2022
    Inventors: Phil Marchand, John C. Thress, Jacob F. Louw, Brian J. Cox, Richard Quick
  • Patent number: 11179159
    Abstract: Methods of implanting a device in the lumen of a blood vessel are described. The method includes providing a microcatheter and a device. The device includes a first hub, a second hub, a support structure including a plurality of struts disposed between the first hub and the second hub, and a layer of material disposed over the plurality of struts. The support structure has a low profile, radially constrained state with an elongated tubular configuration suitable for delivery from a microcatheter. The support structure also has an expanded state, a smooth outer surface, and has an axially shortened configuration relative to the radially constrained state. The microcatheter is advanced to a region of interest within the blood vessel. The support structure is advanced through the lumen of and out the distal end of the microcatheter where it expands to the expanded state.
    Type: Grant
    Filed: May 15, 2017
    Date of Patent: November 23, 2021
    Assignee: SEQUENT MEDICAL, INC.
    Inventors: Brian J. Cox, Dean Schaefer, Robert F. Rosenbluth
  • Publication number: 20210330344
    Abstract: A method and apparatus for treating a clot in the blood vessel of a patient, and particularly the treatment of a pulmonary embolism is disclosed. The treatment includes restoring flow through the clot followed by clot removal, either partially or substantially completely. The clot treatment device is expandable into the blood vessel and may contain radial extensions that assist in restoring flow as well as in removing clot material.
    Type: Application
    Filed: June 26, 2020
    Publication date: October 28, 2021
    Inventors: Robert F. Rosenbluth, Brian J. Cox, Paul Lubock, Richard Quick
  • Patent number: 11147571
    Abstract: A system and method for managing an occlusion, such as a blood clot, within a lumen or passageway of a patient. More particularly, a system and method for rapidly restoring blood flow through an occlusion including a self-expanding, tubular member through which blood may flow when in an expanded state. The tubular member has a structure configured to engage the occlusive material, thereby allowing for extraction of at least a portion of the occlusive material. The system may further employ a material extraction member that is deployed distally of the tubular member.
    Type: Grant
    Filed: August 13, 2018
    Date of Patent: October 19, 2021
    Assignee: Inari Medical, Inc.
    Inventors: Brian J. Cox, Paul Lubock, Robert F. Rosenbluth
  • Publication number: 20210259699
    Abstract: An occlusion device including a tubular braided member having a first end and a second end and extending along a longitudinal axis, the tubular braided member having a repeating pattern of larger diameter portions and smaller diameter portions arrayed along the longitudinal axis, and at least one metallic coil member extending coaxially along at least a portion of the braided member, the at least one metallic coil member having an outer diameter and an inner diameter, wherein the smaller diameter portions of the tubular braided member have an outer diameter and an inner diameter, and wherein at least one of the outer diameter and inner diameter of the tubular braided member is configured to closely match a directly opposing diameter of the metallic coil member.
    Type: Application
    Filed: May 7, 2021
    Publication date: August 26, 2021
    Applicant: Sequent Medical, Inc.
    Inventors: Robert Rosenbluth, Brian J. Cox, William R. Patterson
  • Publication number: 20210236148
    Abstract: Systems and methods for removal of thrombus from a blood vessel in a body of a patient are disclosed herein. The method can include: providing a thrombus extraction device including a proximal self-expanding member formed of a fenestrated structure, a substantially cylindrical portion formed of a net-like filament mesh structure having a proximal end coupled to a distal end of the fenestrated structure; advancing a catheter constraining the thrombus extraction device through a vascular thrombus, deploying the thrombus extraction device by stacking a portion of the net-like filament mesh structure outside of the catheter by distally advancing the self-expanding member until the self-expanding member is beyond a distal end of the catheter; retracting the self-expanding member to unstack the portion of the net-like filament mesh structure and to capture the portion of the thrombus; and withdrawing the thrombus extraction device from the body.
    Type: Application
    Filed: January 21, 2021
    Publication date: August 5, 2021
    Inventors: Phil Marchand, Benjamin E. Merritt, John C. Thress, Jacob F. Louw, Paul Lubock, Brian J. Cox
  • Publication number: 20210214868
    Abstract: Methods of braiding using a braiding mechanism are described. The braiding mechanism includes an array of filament engagement elements, a mandrel extending from the center of the circular array, a plurality of actuators disposed operably about the array, and a rotating mechanism adapted to rotate one or more filaments. The plurality of filaments are loaded onto the mandrel by looping a middle portion of each filament of the plurality of filaments over an end of the mandrel and extend radially toward and contact the circumferential edge of the circular array of filament engagement elements. The plurality of actuators are operated to engage a first subset of the plurality of filaments and move the engaged filaments in a generally radial direction to a position beyond the circumferential edge of the array. The rotating mechanism is operated to move the engaged filaments about the mandrel axis.
    Type: Application
    Filed: December 22, 2020
    Publication date: July 15, 2021
    Inventors: James M. Thompson, Brian J. Cox, Robert Rosenbluth, Philippe Marchand, John Nolting, Darrin J. Kent, Tan Q. Dinh, Hung P. Tran, James A. Millburn
  • Patent number: 11058445
    Abstract: A device and method for intravascular treatment of an embolism, and particularly a pulmonary embolism, is disclosed herein. One aspect of the present technology, for example, is directed toward a clot treatment device that includes a support member having a plurality of first clot engagement members and second clot engagement members positioned about the circumference of a distal portion of the support member. In an undeployed state, individual first clot engagement members can be linear and have a first length, and individual second clot engagement members can be linear and have a second length that is less than the first length. The clot engagement members can be configured to penetrate clot material along an arcuate path and hold clot material to the clot treatment device.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: July 13, 2021
    Assignee: Inari Medical, Inc.
    Inventors: Brian J. Cox, Paul Lubock, Robert Rosenbluth, Richard Quick, Philippe Marchand
  • Patent number: 11058451
    Abstract: Systems and methods for removal of thrombus from a blood vessel in a body of a patient are disclosed herein. The method can include: providing a thrombus extraction device including a proximal self-expanding member formed of a unitary fenestrated structure, a distal substantially cylindrical portion formed of a net-like filament mesh structure, and an inner shaft member connected to a distal end of the net-like filament mesh structure; advancing a catheter constraining the thrombus extraction device through a vascular thrombus, deploying the thrombus extraction; retracting the thrombus extraction device to separate a portion of the thrombus from the vessel wall and to capture the portion of the thrombus within the net-like filament mesh structure; and withdrawing the thrombus extraction device from the body to remove thrombus from the patient.
    Type: Grant
    Filed: May 29, 2019
    Date of Patent: July 13, 2021
    Assignee: Inari Medical, Inc.
    Inventors: Phil Marchand, John C. Thress, Jacob F. Louw, Brian J. Cox, Richard Quick
  • Patent number: 10912577
    Abstract: Systems and methods for removal of thrombus from a blood vessel in a body of a patient are disclosed herein. The method can include: providing a thrombus extraction device including a proximal self-expanding member formed of a fenestrated structure, a substantially cylindrical portion formed of a net-like filament mesh structure having a proximal end coupled to a distal end of the fenestrated structure; advancing a catheter constraining the thrombus extraction device through a vascular thrombus, deploying the thrombus extraction device by stacking a portion of the net-like filament mesh structure outside of the catheter by distally advancing the self-expanding member until the self-expanding member is beyond a distal end of the catheter; retracting the self-expanding member to unstack the portion of the net-like filament mesh structure and to capture the portion of the thrombus; and withdrawing the thrombus extraction device from the body.
    Type: Grant
    Filed: October 15, 2018
    Date of Patent: February 9, 2021
    Assignee: Inari Medical, Inc.
    Inventors: Phil Marchand, Benjamin E. Merritt, John C. Thress, Jacob F. Louw, Paul Lubock, Brian J. Cox
  • Patent number: 10907283
    Abstract: Methods of braiding using a braiding mechanism are described. The braiding machine includes first and second annular members, the second annular member being concentric with the first annular member. A mandrel extends perpendicularly to and intersects a horizontal plane defined by a substantially circular region of the second annular member substantially at the center of the circular region. Each of the annular members has a plurality of tubular guide wires slideably mounted thereon and a plurality of wires extend from the mandrel through each of the tubular wire guides. The first annular member rotates circumferentially relative to the second annular member. The first plurality of tubular wire guides slides radially inward to align with the second annular member, and the second plurality of tubular wire guides slides radially outward so as to align with the first annular member.
    Type: Grant
    Filed: February 27, 2019
    Date of Patent: February 2, 2021
    Assignee: SEQUENT MEDICAL, INC.
    Inventors: James M Thompson, Brian J Cox, Robert Rosenbluth, Philippe Marchand, John Nolting, Darrin J Kent, Tan Q Dinh, Hung P Tran, James A Milburn
  • Publication number: 20200281603
    Abstract: Methods and devices for treatment of a patient's cerebral aneurysm is described. The device includes a permeable shell having a radially constrained elongated state configured for delivery within a catheter lumen, an expanded state with a longitudinally shortened configuration relative to the radially constrained state, and a plurality of elongate filaments that are woven together to form a mesh. The proximal ends of each of the plurality of filaments are gathered by a proximal hub and the distal ends of each of the plurality of filaments are gathered by a distal hub. The proximal portion of the permeable shell includes a swellable polymer. The method includes advancing the implant in a microcatheter to a region of interest in the cerebral vasculature, deploying the implant within the cerebral aneurysm, and withdrawing the microcatheter from the region of interest after deploying the implant.
    Type: Application
    Filed: February 27, 2020
    Publication date: September 10, 2020
    Inventors: Philippe Marchand, Brian J. Cox, Robert F. Rosenbluth
  • Publication number: 20200261098
    Abstract: A vascular occlusion device includes a braided filament mesh structure defining a longitudinal axis. The mesh structure has a relaxed configuration in which it has an axial array of radially-extending occlusion regions, each of which has a proximal side and a distal side meeting at a peripheral edge, the sides of each occlusion region forming a first angle relative to the longitudinal axis. Each occlusion region is axially separated from the adjacent occlusion region by a reduced-diameter connecting region. The mesh structure is radially compressible to a compressed state in which it is deployed intravascularly to a target site through a catheter. Upon deployment, the device radially expands to a constrained configuration in which the peripheral edges of the occlusion regions engage the vascular wall, and the sides of the occlusion regions form a second angle relative to the longitudinal axis that is smaller than the first angle.
    Type: Application
    Filed: April 29, 2020
    Publication date: August 20, 2020
    Inventors: Paul Lubock, Richard Quick, Robert Rosenbluth, Brian J. Cox
  • Patent number: 10709471
    Abstract: A method and apparatus for treating a clot in the blood vessel of a patient, and particularly the treatment of a pulmonary embolism is disclosed. The treatment includes restoring flow through the clot followed by clot removal, either partially or substantially completely. The clot treatment device is expandable into the blood vessel and may contain radial extensions that assist in restoring flow as well as in removing clot material.
    Type: Grant
    Filed: April 10, 2018
    Date of Patent: July 14, 2020
    Assignee: Inari Medical, Inc.
    Inventors: Robert F. Rosenbluth, Brian J. Cox, Paul Lubock, Richard Quick
  • Patent number: 10660648
    Abstract: A vascular occlusion device includes a braided filament mesh structure defining a longitudinal axis. The mesh structure has a relaxed configuration in which it has an axial array of radially-extending occlusion regions, each of which has a proximal side and a distal side meeting at a peripheral edge, the sides of each occlusion region forming a first angle relative to the longitudinal axis. Each occlusion region is axially separated from the adjacent occlusion region by a reduced-diameter connecting region. The mesh structure is radially compressible to a compressed state in which it is deployed intravascularly to a target site through a catheter. Upon deployment, the device radially expands to a constrained configuration in which the peripheral edges of the occlusion regions engage the vascular wall, and the sides of the occlusion regions form a second angle relative to the longitudinal axis that is smaller than the first angle.
    Type: Grant
    Filed: June 25, 2019
    Date of Patent: May 26, 2020
    Assignee: Inceptus Medical, LLC
    Inventors: Paul Lubock, Richard Quick, Robert Rosenbluth, Brian J. Cox