Patents by Inventor Brian J. Frankowski

Brian J. Frankowski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9296990
    Abstract: An oxygen depletion device. The device has a cartridge; a plurality of hollow fibers extending within the cartridge from an entrance to an exit thereof; an amount of an oxygen scavenger packed within the cartridge and contiguous to and in between the plurality of hollow fibers. The hollow fibers are adapted to receiving and conveying red blood cells. There is another embodiment of an oxygen depletion device and method for removing oxygen from red blood cells.
    Type: Grant
    Filed: September 26, 2013
    Date of Patent: March 29, 2016
    Assignees: New Health Sciences, Inc., University of Pittsburgh-of the Commonwealth System of Higher Education
    Inventors: William J. Federspiel, Brian J. Frankowski, Tatsuro Yoshida, Paul J. Vernucci
  • Publication number: 20140228741
    Abstract: A system for intracorporeal gas exchange includes a flexible, rotatable shaft; a plurality of axially spaced agitation mechanisms positioned on the rotatable shaft, such that the rotatable shaft can flex between the axially spaced agitation mechanisms; a plurality of hollow gas permeable fibers adapted to permit diffusion of gas between intracorporeal fluid and an interior of the hollow fibers. The plurality of hollow fibers is positioned radially outward from the agitation mechanisms. A blood contacting medical system includes at least one seal, and a purge system via which a flushing fluid is introduced under pressure over a blood-side face of the seal and caused to flow through a space on the blood side of the seal. The system can further include a rotatable member. The space on the blood side of the seal can be in fluid connection with an annular space adjacent to a rotating element operatively connected to the rotatable member.
    Type: Application
    Filed: April 14, 2014
    Publication date: August 14, 2014
    Applicant: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: BRIAN J. FRANKOWSKI, WILLIAM J. FEDERSPIEL, KEVIN M. MIHELC, SAMUEL C. LIEBER
  • Patent number: 8734382
    Abstract: A system for intracorporeal gas exchange includes a flexible, rotatable shaft; a plurality of axially spaced agitation mechanisms positioned on the rotatable shaft, such that the rotatable shaft can flex between the axially spaced agitation mechanisms; a plurality of hollow gas permeable fibers adapted to permit diffusion of a gas between an intracorporeal fluid and an interior of the hollow fibers. The plurality of hollow fibers is positioned radially outward from the agitation mechanisms. A blood contacting medical system includes at least one seal, and a purge system via which a flushing fluid is introduced under pressure over a blood-side face of the at least one seal and caused to flow through a space on the blood-side face of the at least one seal. The system can further include a rotatable member. The space on the blood-side face of the at least one seal can be in fluid connection with an annular space adjacent to a rotating element operatively connected to the rotatable member.
    Type: Grant
    Filed: February 6, 2009
    Date of Patent: May 27, 2014
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Brian J. Frankowski, William J. Federspiel, Kevin M. Mihelc, Samuel C. Lieber
  • Publication number: 20140065016
    Abstract: A paracorporeal respiratory assist lung is configured with an annular cylindrical hollow fiber membrane (fiber bundle) that is rotated at rapidly varying speeds. Fluid (for example, blood) is introduced to the center of the device and is passed radially through the fiber bundle. The bundle is rotated at rapidly changing velocities with a rotational actuator (for example, a motor or magnetic coupling). The rotation of the fiber bundle provides centrifugal kinetic energy to the fluid giving the device pumping capabilities and may create Taylor vortexes to increase mass transfer. Rotation of the fiber bundle increases the relative velocity between the fluid and the hollow fibers and increases the mass transfer. The porosity of the fiber bundle may be varied to enhance gas exchange with the blood. Alternatively, a rotating core may be used with a stationary fiber bundle.
    Type: Application
    Filed: April 11, 2011
    Publication date: March 6, 2014
    Applicant: UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: William J. FEDERSPIEL, Brian J. FRANKOWSKI, Brendan C. MACK, Scott W. MORLEY, Meir ROSENBERG, Robert G. SVITEK
  • Patent number: 8647569
    Abstract: A paracorporeal respiratory assist lung is configured with an annular cylindrical hollow fiber membrane (fiber bundle) that is rotated at rapidly varying speeds. Fluid (for example, blood) is introduced to the center of the device and is passed radially through the fiber bundle. The bundle is rotated at rapidly changing velocities with a rotational actuator (for example, a motor or magnetic coupling). The rotation of the fiber bundle provides centrifugal kinetic energy to the fluid giving the device pumping capabilities and may create Taylor vortexes to increase mass transfer. Rotation of the fiber bundle increases the relative velocity between the fluid and the hollow fibers and increases the mass transfer. The porosity of the fiber bundle may be varied to enhance gas exchange with the blood. Alternatively, a rotating core may be used with a stationary fiber bundle.
    Type: Grant
    Filed: April 11, 2011
    Date of Patent: February 11, 2014
    Assignee: ALung Technologies, Inc
    Inventors: William J. Federspiel, Brian J. Frankowski, Brendan C. Mack, Scott W. Morley, Meir Rosenberg, Robert G. Svitek
  • Publication number: 20140030694
    Abstract: An oxygen depletion device. The device has a cartridge; a plurality of hollow fibers extending within the cartridge from an entrance to an exit thereof; an amount of an oxygen scavenger packed within the cartridge and contiguous to and in between the plurality of hollow fibers. The hollow fibers are adapted to receiving and conveying red blood cells. There is another embodiment of an oxygen depletion device and method for removing oxygen from red blood cells.
    Type: Application
    Filed: September 26, 2013
    Publication date: January 30, 2014
    Applicants: University of Pittsburgh - Of the Commonwealth System of Higher Education, New Health Sciences, Inc.
    Inventors: William J. FEDERSPIEL, Brian J. FRANKOWSKI, Tatsuro YOSHIDA, Paul J. VERNUCCI
  • Patent number: 8569052
    Abstract: An oxygen depletion device. The device has a cartridge; a plurality of hollow fibers extending within the cartridge from an entrance to an exit thereof; an amount of an oxygen scavenger packed within the cartridge and contiguous to and in between the plurality of hollow fibers. The hollow fibers are adapted to receiving and conveying red blood cells. There is another embodiment of an oxygen depletion device and method for removing oxygen from red blood cells.
    Type: Grant
    Filed: May 25, 2011
    Date of Patent: October 29, 2013
    Assignees: New Health Sciences, Inc., University of Pittsburgh-Of the Commonwealth System of Higher Education
    Inventors: William J. Federspiel, Brian J. Frankowski, Tatsuro Yoshida, Paul J. Vernucci
  • Publication number: 20120100523
    Abstract: An oxygen depletion device. The device has a cartridge; a plurality of hollow fibers extending within the cartridge from an entrance to an exit thereof; an amount of an oxygen scavenger packed within the cartridge and contiguous to and in between the plurality of hollow fibers. The hollow fibers are adapted to receiving and conveying red blood cells. There is another embodiment of an oxygen depletion device and method for removing oxygen from red blood cells.
    Type: Application
    Filed: May 25, 2011
    Publication date: April 26, 2012
    Inventors: William J. Federspiel, Brian J. Frankowski, Tatsuro Yoshida, Paul J. Vernucci
  • Patent number: 7927544
    Abstract: A paracorporeal respiratory assist lung is configured with an annular cylindrical hollow fiber membrane (fiber bundle) that is rotated at rapidly varying speeds. Fluid (for example, blood) is introduced to the center of the device and is passed radially through the fiber bundle. The bundle is rotated at rapidly changing velocities with a rotational actuator (for example, a motor or magnetic coupling). The rotation of the fiber bundle provides centrifugal kinetic energy to the fluid giving the device pumping capabilities and may create Taylor vortexes to increase mass transfer. Rotation of the fiber bundle increases the relative velocity between the fluid and the hollow fibers and increases the mass transfer. The porosity of the fiber bundle may be varied to enhance gas exchange with the blood. Alternatively, a rotating core may be used with a stationary fiber bundle.
    Type: Grant
    Filed: April 21, 2006
    Date of Patent: April 19, 2011
    Assignee: Alung Technologies, Inc.
    Inventors: William J. Federspiel, Brian J. Frankowski, Brendan C. Mack, Scott W. Morley, Meir Rosenberg, Robert G. Svitek
  • Publication number: 20100331767
    Abstract: A system for intracorporeal gas exchange includes a flexible, rotatable shaft; a plurality of axially spaced agitation mechanisms positioned on the rotatable shaft, such that the rotatable shaft can flex between the axially spaced agitation mechanisms; a plurality of hollow gas permeable fibers adapted to permit diffusion of gas between intracorporeal fluid and an interior of the hollow fibers. The plurality of hollow fibers is positioned radially outward from the agitation mechanisms. A blood contacting medical system includes at least one seal, and a purge system via which a flushing fluid is introduced under pressure over a blood-side face of the seal and caused to flow through a space on the blood side of the seal. The system can further include a rotatable member. The space on the blood side of the seal can be in fluid connection with an annular space adjacent to a rotating element operatively connected to the rotatable member.
    Type: Application
    Filed: February 6, 2009
    Publication date: December 30, 2010
    Inventors: Brian J. Frankowski, William J. Federspiel, Kevin M. Mihelc, Samuel C. Lieber
  • Publication number: 20040225233
    Abstract: A system for placement of a medical device in a body passage including a first and second guidewire, each configured with magnets on their distal ends. The guidewires are inserted through different access sites of a body passage and blindly connected using the magnets. The first guidewire is inserted into a first insertion site and the second guidewire is inserted into a second insertion site. Once the distal ends of the guidewires are attached, the second guidewire can then be removed from the first insertion site, detached from the first guidewire and attached to a medical device. The distal end of the second guidewire can then be pulled through the second insertion site to guide the medical device into a desired location in the body passage.
    Type: Application
    Filed: May 9, 2003
    Publication date: November 11, 2004
    Inventors: Brian J. Frankowski, William J. Federspiel, Joseph F. Golob, Brack G. Hattler