Patents by Inventor Brian J. Hicke

Brian J. Hicke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acid ligands to the prostate specific membrane antigen
    Patent number: 6933114
    Abstract: Methods are provided for generating nucleic acid ligands of Prostate Specific Membrane Antigen (PSMA). The methods of the invention use the SELEX method for the isolation of nucleic acid ligands. The invention also includes nucleic acid ligands to PSMA, and methods and compositions for the treatment and diagnosis of disease using the nucleic acid ligands.
    Type: Grant
    Filed: October 16, 2001
    Date of Patent: August 23, 2005
    Assignee: Gilead Sciences, Inc.
    Inventors: Shawn E. Lupold, Yun Lin, Brian J. Hicke, Donald S. Coffey
  • Nucleic acid ligands to the prostate specific membrane antigen
    Publication number: 20020119473
    Abstract: Methods are provided for generating nucleic acid ligands of Prostate Specific Membrane Antigen (PSMA). The methods of the invention use the SELEX method for the isolation of nucleic acid ligands. The invention also includes nucleic acid ligands to PSMA, and methods and compositions for the treatment and diagnosis of disease using the nucleic acid ligands.
    Type: Application
    Filed: October 16, 2001
    Publication date: August 29, 2002
    Inventors: Shawn E. Lupold, Yun Lin, Brian J. Hicke, Donald S. Coffey
  • High affinity nucleic acid ligands to lectins
    Patent number: 6001988
    Abstract: This invention discloses high-affinity oligonucleotide ligands to lectins, specifically nucleic acid ligands having the ability to bind to the lectins, wheat germ agglutinin, L-selectin, E-selectin and P-selectin. Also disclosed are the methods for obtaining such ligands.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: December 14, 1999
    Assignee: NeXstar Pharmaceuticals, Inc.
    Inventors: David H. Parma, Brian J. Hicke, Philippe Bridonneau, Larry Gold