Abstract: Disclosed herein are methods of treatment comprising administering a therapeutically effective amount of a myosin modulator or a pharmaceutically acceptable salt thereof to a subject in need thereof and diagnostic methods useful in connection with those treatments. Due to observations unfolding in clinical trials with mavacamten and with mavacamten and other myosin inhibitors in the pre-clinical setting, new insights into how myosin inhibitors can be used beneficially to impact the disease state of HCM and other diseases are provided herein.

Abstract: A knock-down portable partition system has cover panels supported on a post and beam framework designed for quick and easy on-site manual assembly. The framework includes at least two vertical posts and at least two structural beams rigidly, yet detachably interconnecting the vertical posts. Connectors secure the beams to the posts, such that the partition system can be assembled and disassembled manually. The partition system may include utility troughs shaped to retain wires, cabling, etc. therein to provide power and/or communication to the system. The utility troughs have opposite ends shaped to be detachably mounted to the posts.

Abstract: A knock-down portable partition system has cover panels supported on a post and beam framework designed for quick and easy on-site manual assembly. The framework includes at least two vertical posts and at least two structural beams rigidly, yet detachably interconnecting the vertical posts. Connectors secure the beams to the posts, such that the partition system can be assembled and disassembled manually. The partition system may include utility troughs shaped to retain wires, cabling, etc. therein to provide power and/or communication to the system. The utility troughs have opposite ends shaped to be detachably mounted to the posts.

Abstract: What is disclosed is a non-return valve comprising a sealing piston which is biased against a valve seat in the basic position inside a valve housing, and which is manufactured by a plastics injection molding technique.

Abstract: A knock-down portable partition system has cover panels supported on a post and beam framework designed for quick and easy on-site manual assembly. The framework includes at least two vertical posts and at least two structural beams rigidly, yet detachably interconnecting the vertical posts. Connectors secure the beams to the posts, such that the partition system can be assembled and disassembled manually. The partition system may include utility troughs shaped to retain wires, cabling, etc. therein to provide power and/or communication to the system. The utility troughs have opposite ends shaped to be detachably mounted to the posts.

Abstract: A knock-down portable partition system has cover panels supported on a post and beam framework designed for quick and easy on-site manual assembly. The framework includes at least two vertical posts and at least two structural beams rigidly, yet detachably interconnecting the vertical posts. Connectors secure the beams to the posts, such that the partition system can be assembled and disassembled manually. The partition system may include utility troughs shaped to retain wires, cabling, etc. therein to provide power and/or communication to the system. The utility troughs have opposite ends shaped to be detachably mounted to the posts.

Abstract: A knock-down partition panel frame includes a pair of spaced apart generally upright posts, each having at least one receptacle defining a tapered surface. The partition panel frame further includes at least one generally horizontal member extending between and interconnecting the posts. The horizontal member includes fastenerless connectors at opposite ends thereof, each having at least one connecting element engaging with the tapered surface to thereby securely interconnect the posts and the horizontal member to define a rigid partition frame having an interior space. A cover panel is secured to the partition frame, and closes off at least a portion of the interior space.

Abstract: A knock-down portable partition includes a rigid panel frame having a central portion. The partition includes at least one cover panel covering at least a portion of the central portion of the rigid panel frame. Connectors detachably mount the cover panel on the panel frame to facilitate assembly and removal of the cover panel on the panel frame. The rigid panel frame includes at least two vertical posts having an upper end, a lower end, and opposite side faces. The opposite faces have at least two beam connection ports thereon positioned adjacent the upper and lower ends of the associated one of the posts. The panel frame also includes upper and lower beams extending generally horizontally between the vertical posts adjacent the upper and lower ends thereof, and interconnecting the vertical posts adjacent the connection ports. The panel frame includes quick-disconnect connectors such as movable lock members positioned on one of the posts and the beams adjacent the connection ports.

Abstract: A screen assembly is adapted to connect to a partition of the type having at least one upright frame member with openings in opposite side faces thereof to receive support hooks of hang-on accessory units. The screen assembly includes a sheet member defining at least one side edge, and a bracket is connected to the sheet member adjacent the side edge. The bracket includes a first member configured to extend around at least a portion of a first side of the upright frame member. The first member includes a connector adapted to engage the openings in the first side face of the upright frame member. The bracket also includes a second member configured to extend around at least a portion of a second side of the upright frame member. The second member includes a connector adapted to engage openings in a second side face of the upright frame member.

Abstract: A partition includes at least two vertical posts with upper and lower beams having opposite ends thereof interconnecting the vertical posts to define when in an assembled condition, a rigid panel frame having a substantially open interior. The panel frame defines a vertical dimension. At least one cover panel is configured to enclose at least a portion of the open interior of the panel frame, and is removably mounted on the panel frame to readily access the open interior thereof. The cover panel defines an interior surface and a center portion spaced-apart from the posts. A cover panel brace is connected with the upper beam, and has an outer surface abutting the interior surface of the cover panel to support the cover panel adjacent the center portion to prevent flexing of the cover panel. The cover panel brace is longitudinally extensible to accommodate variations of the vertical dimension between the upper and lower beams.