Patents by Inventor Brian J. Kelley

Brian J. Kelley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8906354
    Abstract: The present invention relates to a loaded particle comprising at least one fluorescent dye, and in particular, a fluorescent dye with a large Stokes shift. The invention further relates to a method for producing an loaded latex particle, loaded with a fluorescent dye having a large stokes shift. In addition, the present invention relates to latex particles loaded with fluorescent dyes that are organic solvent soluble and insoluble in water. In a preferred embodiment, when the dyes are loaded into the water soluble latex particle, an increase is observed in quantum yield of fluorescence as compared to the quantum yield of the dye in aqueous solvent.
    Type: Grant
    Filed: March 8, 2011
    Date of Patent: December 9, 2014
    Assignee: Bruker Biospin Corporation
    Inventors: Tao Ji, Hans F. Schmitthenner, Yonghong Yang, John W. Harder, Jeffrey W. Leon, William J. Harrison, Brian J. Kelley, James R. Bennett, David A. Stegman, Ruizheng Wang
  • Publication number: 20120058050
    Abstract: The present invention relates to a loaded particle comprising at least one fluorescent dye, and in particular, a fluorescent dye with a large Stokes shift. The invention further relates to a method for producing an loaded latex particle, loaded with a fluorescent dye having a large stokes shift. In addition, the present invention relates to latex particles loaded with fluorescent dyes that are organic solvent soluble and insoluble in water. In a preferred embodiment, when the dyes are loaded into the water soluble latex particle, an increase is observed in quantum yield of fluorescence as compared to the quantum yield of the dye in aqueous solvent.
    Type: Application
    Filed: March 8, 2011
    Publication date: March 8, 2012
    Inventors: Tao Ji, Hans F. Schmitthenner, Yonghong Yang, John W. Harder, Jeffrey W. Leon, William J. Harrison, Brian J. Kelley, James R. Bennett, David A. Stegman, Ruizheng Wang
  • Publication number: 20080181965
    Abstract: The present invention relates to a loaded latex particle comprising a latex material made from a mixture represented by formula (X)m-(Y)n-(Z)o-(W)p, wherein Y is at least one monomer with at least two ethylenically unsaturated chemical functionalities; Z is at least one polyethylene glycol macromonomer with an average molecular weight of between 300 and 10,000; W is an ethylenic monomer different from X, Y, or Z; and X is at least one water insoluble, alkoxethyl containing monomer; and m, n, o, and p are the respective weight percentages of each monomer. The particle may be loaded with a fluorescent dye.
    Type: Application
    Filed: April 3, 2007
    Publication date: July 31, 2008
    Inventors: Jeffrey W. Leon, William J. Harrison, Brian J. Kelley, James R. Bennett, David A. Stegman, Ruizheng Wang, John W. Harder
  • Patent number: 7348147
    Abstract: The present invention relates to a method of detecting nucleic acids comprising suspending at least one recognizable target nucleic acid in a suspending solution containing polymeric particles marked with a probe, wherein the probe has an affinity for the target nucleic acid, adding a recognition unit-peroxidase conjugate marker to the suspending solution, forming a complex of the polymeric particles marked with a probe, the target nucleic acid and the recognition unit-peroxidase conjugate marker, contacting the suspending solution with a gelatin surface, adding a developer to the suspending solution in contact with the gelatin surface in the presence of phenol to attach the complex to the gelatin surface, washing the gelatin surface, and detecting the complex attached to the gelatin surface.
    Type: Grant
    Filed: November 15, 2004
    Date of Patent: March 25, 2008
    Assignee: Carestream Health, Inc.
    Inventors: Tiecheng A. Qiao, Brian J. Kelley
  • Patent number: 7183119
    Abstract: The present invention relates to a method of detecting biological analytes comprising suspending a target analyte in a suspending solution containing polymeric particles marked with a probe, wherein the probe has an affinity for said target analyte; adding recognition unit-peroxidase conjugate marker to the suspending solution; forming a complex of the target analyte, the polymeric particles marked with a probe, and the recognition unit-peroxidase conjugate marker; contacting a gelatin surface with the suspending solution; adding developer to the suspending solution in contact with the gelatin surface in the presence of phenol to attach the complex to the gelatin surface; washing the gelatin surface; and detecting the complex attached to the gelatin surface.
    Type: Grant
    Filed: November 15, 2004
    Date of Patent: February 27, 2007
    Assignee: Eastman Kodak Company
    Inventors: Tiecheng A. Qiao, Brian J. Kelley
  • Patent number: 6428948
    Abstract: The present invention relates to photographic elements, including photographic prints, having a protective overcoat that resists fingerprints, common stains, and spills. More particularly, the present invention provides a processing-solution-permeable protective overcoat that is water resistant in the final processed product and which, at the same time, provides improved wet-abrasion resistance.
    Type: Grant
    Filed: March 13, 2001
    Date of Patent: August 6, 2002
    Assignee: Eastman Kodak Company
    Inventors: Tiecheng A. Qiao, Joseph S. Sedita, Mridula Nair, Brian J. Kelley, Yongcai Wang
  • Publication number: 20020018969
    Abstract: The present invention relates to photographic elements, including photographic prints, having a protective overcoat that resists fingerprints, common stains, and spills. More particularly, the present invention provides a processing-solution-permeable protective overcoat that is water resistant in the final processed product and which, at the same time, provides improved wet-abrasion resistance.
    Type: Application
    Filed: March 13, 2001
    Publication date: February 14, 2002
    Inventors: Tiecheng A. Qiao, Joseph S. Sedita, Mridula Nair, Brian J. Kelley, Yongcai Wang
  • Patent number: 6319658
    Abstract: The present invention is also directed to a method of photoprocessing a photographic imaging element having a processing-solution-permeable overcoat that comprises at least one water-dispersible hydrophobic polymer interspersed with a water-soluble hydrophilic polymer. During photoprocessing, a surface-active water-soluble hydrophilic polymer is leached into a photoprocessing solution. However, foaming due to the hydrophilic polymer in the photoprocessing solution is prevented by the presence of a non-ionic surfactant having an HLB of less than 12.
    Type: Grant
    Filed: September 27, 2000
    Date of Patent: November 20, 2001
    Assignee: Eastman Kodak Company
    Inventors: Lloyd A. Lobo, Tiecheng A. Qiao, Brian J. Kelley
  • Patent number: 6258517
    Abstract: The present invention relates to photographic elements, including photographic prints, having a protective overcoat that resists fingerprints, common stains, and spills. More particularly, the present invention provides a processing-solution-permeable protective overcoat that is water resistant in the final processed product and which, at the same time, provides improved wet-abrasion resistance.
    Type: Grant
    Filed: June 6, 2000
    Date of Patent: July 10, 2001
    Assignee: Eastman Kodak Company
    Inventors: Tiecheng A. Qiao, Joseph S. Sedita, Mridula Nair, Brian J. Kelley, Yongcai Wang