Patents by Inventor Brian J. Kotecki

Brian J. Kotecki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of indazolyl ureas that inhibit Vanilloid subtype 1 (VR1) receptors
    Patent number: 8519186
    Abstract: The present invention relates to a process of preparing indazolyl ureas that are useful as antagonists of the vanilloid receptor subtype 1 (VR1).
    Type: Grant
    Filed: October 28, 2010
    Date of Patent: August 27, 2013
    Assignee: AbbVie Inc.
    Inventors: Kirill A. Lukin, Margaret Chi-Ping Hsu, Dilinie P. Fernando, Brian J. Kotecki, Marvin R. Leanna
  • Process for the synthesis of (2S,3AR,7AS)-octahydro-1H-indole carboxylic acid as an intermediate for trandolapril
    Patent number: 8288565
    Abstract: A process for the preparation of (2S,3aR,7aS)-octahydro-1H-indole-20carboxylic acid hydrochloride.
    Type: Grant
    Filed: July 16, 2010
    Date of Patent: October 16, 2012
    Assignee: Abbott Laboratories
    Inventors: Sanjay R. Chemburkar, Rajarathnam E. Reddy, Douglas M. Reamer, John T. Pavlina, Stephen S. Ulrey, Brian J. Kotecki
  • Methods for making central nervous system agents that are TRPV1 antagonists
    Patent number: 8232411
    Abstract: The invention discloses compounds of formula II: and methods of making the compounds, which are VR1 antagonists that are useful in treating pain, inflammatory thermal hyperalgesia, urinary incontinence and bladder overactivity.
    Type: Grant
    Filed: March 20, 2009
    Date of Patent: July 31, 2012
    Assignee: Abbott Laboratories
    Inventors: Kirill A. Lukin, Brian J. Kotecki, Su Yu, Lei Wang, Anthony R. Haight
  • PROCESS FOR THE SYNTHESIS OF (2S,3AR,7AS)-OCTAHYDRO-1H-INDOLE CARBOXYLIC ACID AS AN INTERMEDIATE FOR TRANDOLAPRIL
    Publication number: 20110065930
    Abstract: A process for the preparation of (2S,3aR,7aS)-octahydro-1H-indole-20carboxylic acid hydrochloride.
    Type: Application
    Filed: July 16, 2010
    Publication date: March 17, 2011
    Applicant: ABBOTT LABORATORIES
    Inventors: Sanjay R. Chemburkar, Rajarathnam E. Reddy, Douglas M. Reamer, John T. Pavlina, Stephen S. Ulrey, Brian J. Kotecki
  • PROCESS FOR THE PREPARATION OF INDAZOLYL UREAS THAT INHIBIT VANILLOID SUBTYPE 1 (VR1) RECEPTORS
    Publication number: 20110040102
    Abstract: The present invention relates to a process of preparing indazolyl ureas that are useful as antagonists of the vanilloid receptor subtype 1 (VR1).
    Type: Application
    Filed: October 28, 2010
    Publication date: February 17, 2011
    Applicant: ABBOTT LABORATORIES
    Inventors: Kirill A. Lukin, Margaret Chi-Ping Hsu, Dilinie P. Fernando, Brian J. Kotecki, Marvin R. Leanna
  • Process for the preparation of indazolyl ureas that inhibit Vanilloid subtype1 (VR1) receptors
    Patent number: 7847104
    Abstract: The present invention relates to a process of preparing indazolyl ureas that are useful as antagonists of the vanilloid receptor subtype 1 (VR1).
    Type: Grant
    Filed: April 13, 2007
    Date of Patent: December 7, 2010
    Assignee: Abbott Laboratories
    Inventors: Kirill A. Lukin, Margaret Chi-Ping Hsu, Dilinie P. Fernando, Brian J. Kotecki, Marvin R. Leanna
  • METHODS FOR MAKING CENTRAL NERVOUS SYSTEM AGENTS THAT ARE TRPV1 ANTAGONISTS
    Publication number: 20100016611
    Abstract: The invention discloses compounds of formula II: and methods of making the compounds, which are VR1 antagonists that are useful in treating pain, inflammatory thermal hyperalgesia, urinary incontinence and bladder overactivity.
    Type: Application
    Filed: March 20, 2009
    Publication date: January 21, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: Kirill A. Lukin, Brian J. Kotecki, Su Yu, Lei Wang, Anthony R. Haight
  • (1S,5S)-3-(5,6-DICHLORO-3-PYRIDINYL)-3,6- DIAZABICYCLO[3.2.0]HEPTANE
    Publication number: 20090203664
    Abstract: The present invention discloses (1S,5S)-3-(5,6-dichloro-3-pyridinyl)-3,6-diazabicyclo[3.2.0]heptane, salts thereof, and its use to treat pain and other disorders associated with the nicotinic acetylcholine receptor.
    Type: Application
    Filed: April 20, 2009
    Publication date: August 13, 2009
    Applicant: ABBOTT LABORATORIES
    Inventors: Michael J. Buckley, Jianguo Ji, Geoff G.Z. Zhang, Rodger F. Henry, Weili W. Wang, Gregory S. Wayne, Wenke Li, Timothy B. Towne, Steven J. Wittenberger, Steven M. Hannick, Brian J. Kotecki, Bryan S. Macri, Timothy A. Robbins
  • (1S,5S)-3-(5,6-dichloro-3-pyridinyl)-3,6-diazabicyclo[3.2.0]heptane
    Patent number: 7538226
    Abstract: The present invention discloses (1S,5S)-3-(5,6-dichloro-3-pyridinyl)-3,6-diazabicyclo[3.2.0]heptane, salts thereof, and its use to treat pain and other disorders associated with the nicotinic acetylcholine receptor.
    Type: Grant
    Filed: August 14, 2007
    Date of Patent: May 26, 2009
    Assignee: Abbott Laboratories
    Inventors: Michael J. Buckley, Jianguo Ji, Geoff G. Z. Zhang, Rodger F. Henry, Weili W. Wang, Gregory S. Wayne, Wenke Li, Timothy B. Towne, Steven J. Wittenberger, Steven M. Hannick, Brian J. Kotecki, Bryan S. Macri, Timothy A. Robbins
  • (1S,5S)-3-(5,6-dichloro-3-pyridinyl)-3,6-diazabicyclo[3.2.0]heptane
    Patent number: 7354937
    Abstract: The present invention discloses (1S,5S)-3-(5,6-dichloro-3-pyridinyl)-3,6-diazabicyclo[3.2.0]heptane, salts thereof, and its use to treat pain and other disorders associated with the nicotinic acetylcholine receptor.
    Type: Grant
    Filed: July 7, 2005
    Date of Patent: April 8, 2008
    Assignee: Abbott Laboratories
    Inventors: Michael J. Buckley, Jianguo Ji, Geoff G. Z. Zhang, Rodger F. Henry, Weili W. Wang, Gregory S. Wayne, Wenke Li, Timothy B. Towne, Steven J. Wittenberger, Steven M. Hannick, Brian J. Kotecki, Bryan S. Macri, Timothy A. Robbins