Patents by Inventor Brian J. LINEHAN

Brian J. LINEHAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250255851
    Abstract: Disclosed are solid forms of an inhibitor of aldosterone synthase (ASi) having the formula (1) The invention also relates to methods of making these solid forms, pharmaceutical compositions comprising these solid forms, and their use for medical conditions responsive to treatment with an inhibitor of aldosterone synthase.
    Type: Application
    Filed: February 12, 2025
    Publication date: August 14, 2025
    Inventors: Brian J. LINEHAN, John Andrew SMOLIGA, Zheng Jane LI
  • Publication number: 20240217985
    Abstract: The present invention relates to a crystalline form of an MDM2-p53 inhibitor and methods for its preparation. Furthermore, the invention relates to pharmaceutical compositions comprising an MDM2-p53 inhibitor, preferably the crystalline form of the present invention, and at least one pharmaceutically acceptable excipient as well as to methods for their preparation. The crystalline form of the MDM2-p53 inhibitor of the present invention and the pharmaceutical compositions of the present invention can be used as a medicament, in particular for the treatment of cancer in patients bearing tumors with TP53 wild-type status.
    Type: Application
    Filed: December 21, 2023
    Publication date: July 4, 2024
    Inventors: Fredrik Lars NORDSTROM, Norbert BIRK, Manuel HENRY, Brian J. LINEHAN, Peter SCHNEIDER