Patents by Inventor Brian J. McKeen

Brian J. McKeen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200319219
    Abstract: An automated pre-analytical processing method and an apparatus for pre-analytical processing of samples to be forwarded to an adjacent analyzer for analysis. Rack label information is read and communicated to a processor. From the rack label information, the processor determines where to route the rack. The pre-analytical system has a rack robot that conveys racks to discrete locations depending upon the routing information assigned to the rack by the processor. The pre-analytical system has an automated station that reads the labels of individual sample containers in the rack that are brought to the automated station on instructions from the processor. Depending on the type of sample container and the type of sample disposed therein, the samples are either prepared for analysis by the automated station or the sample containers are directly passed through the automated station. Prepared samples and passed through samples are passed individually to a batching rack.
    Type: Application
    Filed: February 17, 2017
    Publication date: October 8, 2020
    Applicant: Becton Dickinson and Company
    Inventors: MICHAEL T. VANSICKLER, Kevin Bailey, Christopher John Tesluk, Dwight Livingston, Steven C. Rotundo, Stephen Robert LaChance, Michael J. Touma, Brian James McKeen, Gerard Sevigny
  • Patent number: 10345205
    Abstract: Sample application systems can include an extraction mechanism to remove a sample from sample containers, a sample vessel disposed on a deployment mechanism, where the deployment mechanism is arranged to move the sample vessel to receive a sample, an extraction mechanism washing station to wash the extraction mechanism, a sample applicator to remove a portion of the sample in the sample vessel and apply it onto a sample carrier, where the deployment mechanism can move the sample vessel to a sample application position, a sample vessel washing station to wash the sample vessel, where the deployment mechanism can move the sample vessel to the sample vessel washing station, a sample applicator washing station to wash the sample applicator after the sample has been dispensed onto the sample carrier, and a fluid control system to control flow of a fluid provided to the extraction mechanism and the sample applicator.
    Type: Grant
    Filed: March 6, 2017
    Date of Patent: July 9, 2019
    Assignee: Roche Diagnostics Hematology, Inc.
    Inventors: Brian J. McKeen, Eric D. Yeaton, James L. Dowling, David Zahniser, Stephen Conroy
  • Patent number: 10175153
    Abstract: The systems and methods disclosed herein permit automated preparation of biological specimens for examination. The disclosed systems and methods provide fast, efficient, and highly uniform specimen processing using minimal quantities of fluids. The methods include at least a fixing phase for fixing a biological specimen to a substrate such as a microscope slide, a staining phase for staining the specimen, and a rinsing phase for rinsing the specimen. One or more of the fixing, staining, and rinsing phases include one or more agitation cycles for distributing reagents evenly and uniformly across the specimen. The systems can be implemented as a standalone device or as a component in a larger system for preparing and examining biological specimens.
    Type: Grant
    Filed: August 24, 2015
    Date of Patent: January 8, 2019
    Assignee: Roche Diagnostics Hematology, Inc.
    Inventors: Daniel Lapen, David Zahniser, Mark Licari, Brian J. McKeen, Eric D. Yeaton, Dennis Poole
  • Publication number: 20180238781
    Abstract: The apparatus disclosed herein features a substrate arm and gripper, a platform having a top surface located opposite the substrate when the substrate arm is in a specimen processing position and featuring at least one fluid port located on a surface of the platform facing the substrate and at least one vacuum port located on the surface of the platform facing the substrate, and during operation, the apparatus is configured to (a) dispense a first quantity of fluid from the at least one fluid port to fill a separation between the substrate and the platform, (b) dispense an additional quantity of fluid from the at least one fluid port into the separation to displace a portion of the first quantity of fluid, and (c) remove the portion of the first quantity of fluid from the separation through the at least one vacuum port.
    Type: Application
    Filed: February 12, 2018
    Publication date: August 23, 2018
    Inventors: Daniel Lapen, David Zahniser, Mark Licari, Brian J. McKeen, Eric D. Yeaton, Dennis Poole, Stephen Conroy
  • Patent number: 9891147
    Abstract: The apparatus disclosed herein features a substrate arm and gripper, a platform having a top surface located opposite the substrate when the substrate arm is in a specimen processing position and featuring at least one fluid port located on a surface of the platform facing the substrate and at least one vacuum port located on the surface of the platform facing the substrate, and during operation, the apparatus is configured to (a) dispense a first quantity of fluid from the at least one fluid port to fill a separation between the substrate and the platform, (b) dispense an additional quantity of fluid from the at least one fluid port into the separation to displace a portion of the first quantity of fluid, and (c) remove the portion of the first quantity of fluid from the separation through the at least one vacuum port.
    Type: Grant
    Filed: April 4, 2014
    Date of Patent: February 13, 2018
    Assignee: Roche Diagnostics Hematology, Inc.
    Inventors: Daniel Lapen, David Zahniser, Mark Licari, Brian J. McKeen, Eric D. Yeaton, Dennis Poole, Stephen Conroy
  • Publication number: 20170241875
    Abstract: Sample application systems can include an extraction mechanism to remove a sample from sample containers, a sample vessel disposed on a deployment mechanism, where the deployment mechanism is arranged to move the sample vessel to receive a sample, an extraction mechanism washing station to wash the extraction mechanism, a sample applicator to remove a portion of the sample in the sample vessel and apply it onto a sample carrier, where the deployment mechanism can move the sample vessel to a sample application position, a sample vessel washing station to wash the sample vessel, where the deployment mechanism can move the sample vessel to the sample vessel washing station, a sample applicator washing station to wash the sample applicator after the sample has been dispensed onto the sample carrier, and a fluid control system to control flow of a fluid provided to the extraction mechanism and the sample applicator.
    Type: Application
    Filed: March 6, 2017
    Publication date: August 24, 2017
    Inventors: Brian J. McKeen, Eric D. Yeaton, James L. Dowling, David Zahniser, Stephen Conroy
  • Patent number: 9588026
    Abstract: Sample application systems can include an extraction mechanism to remove a sample from sample containers, a sample vessel disposed on a deployment mechanism, where the deployment mechanism is arranged to move the sample vessel to receive a sample, an extraction mechanism washing station to wash the extraction mechanism, a sample applicator to remove a portion of the sample in the sample vessel and apply it onto a sample carrier, where the deployment mechanism can move the sample vessel to a sample application position, a sample vessel washing station to wash the sample vessel, where the deployment mechanism can move the sample vessel to the sample vessel washing station, a sample applicator washing station to wash the sample applicator after the sample has been dispensed onto the sample carrier, and a fluid control system to control flow of a fluid provided to the extraction mechanism and the sample applicator.
    Type: Grant
    Filed: June 12, 2015
    Date of Patent: March 7, 2017
    Assignee: Roche Diagnostics Hematology, Inc.
    Inventors: Brian J. McKeen, Eric D. Yeaton, James L. Dowling, David Zahniser, Stephen Conroy
  • Patent number: 9435818
    Abstract: Sample transport systems are described that move a sample carrier from one station to a next station in a sample processing systems. The systems include: a translating member; two or more sample carrier retaining devices attached to the translating member, wherein each of the two or more sample carrier retaining devices can include a retainer portion to temporarily retain one or more sample carriers; and a movement mechanism to move the translating member and the attached sample carrier retaining devices between a first position and a second position; wherein the sample carrier retaining devices are controlled and moved simultaneously to retain a sample carrier when the translating member reaches the first position and to release a sample carrier when the translating member reaches the second position to successively advance sample carriers in the sample processing systems.
    Type: Grant
    Filed: July 13, 2012
    Date of Patent: September 6, 2016
    Assignee: Roche Diagnostics Hematology, Inc.
    Inventors: Brian J. McKeen, Eric D. Yeaton, James L. Dowling
  • Publication number: 20160209302
    Abstract: The systems and methods disclosed herein permit automated preparation of biological specimens for examination. The disclosed systems and methods provide fast, efficient, and highly uniform specimen processing using minimal quantities of fluids. The methods include at least a fixing phase for fixing a biological specimen to a substrate such as a microscope slide, a staining phase for staining the specimen, and a rinsing phase for rinsing the specimen. One or more of the fixing, staining, and rinsing phases include one or more agitation cycles for distributing reagents evenly and uniformly across the specimen. The systems can be implemented as a standalone device or as a component in a larger system for preparing and examining biological specimens.
    Type: Application
    Filed: August 24, 2015
    Publication date: July 21, 2016
    Inventors: Daniel Lapen, David Zahniser, Mark Licari, Brian J. McKeen, Eric D. Yeaton, Dennis Poole
  • Publication number: 20160018302
    Abstract: The apparatus disclosed herein features a substrate arm and gripper, a platform having a top surface located opposite the substrate when the substrate arm is in a specimen processing position and featuring at least one fluid port located on a surface of the platform facing the substrate and at least one vacuum port located on the surface of the platform facing the substrate, and during operation, the apparatus is configured to (a) dispense a first quantity of fluid from the at least one fluid port to fill a separation between the substrate and the platform, (b) dispense an additional quantity of fluid from the at least one fluid port into the separation to displace a portion of the first quantity of fluid, and (c) remove the portion of the first quantity of fluid from the separation through the at least one vacuum port.
    Type: Application
    Filed: April 4, 2014
    Publication date: January 21, 2016
    Applicant: Roche Diagnostics Hematology, Inc.
    Inventors: Daniel Lapen, David Zahniser, Mark Licari, Brian J. McKeen, Eric D. Yeaton, Dennis Poole, Stephen Conroy
  • Publication number: 20150276565
    Abstract: Sample application systems can include an extraction mechanism to remove a sample from sample containers, a sample vessel disposed on a deployment mechanism, where the deployment mechanism is arranged to move the sample vessel to receive a sample, an extraction mechanism washing station to wash the extraction mechanism, a sample applicator to remove a portion of the sample in the sample vessel and apply it onto a sample carrier, where the deployment mechanism can move the sample vessel to a sample application position, a sample vessel washing station to wash the sample vessel, where the deployment mechanism can move the sample vessel to the sample vessel washing station, a sample applicator washing station to wash the sample applicator after the sample has been dispensed onto the sample carrier, and a fluid control system to control flow of a fluid provided to the extraction mechanism and the sample applicator.
    Type: Application
    Filed: June 12, 2015
    Publication date: October 1, 2015
    Inventors: Brian J. McKeen, Eric D. Yeaton, James L. Dowling
  • Patent number: 9116087
    Abstract: The systems and methods disclosed herein permit automated preparation of biological specimens for examination. The disclosed systems and methods provide fast, efficient, and highly uniform specimen processing using minimal quantities of fluids. The methods include at least a fixing phase for fixing a biological specimen to a substrate such as a microscope slide, a staining phase for staining the specimen, and a rinsing phase for rinsing the specimen. One or more of the fixing, staining, and rinsing phases include one or more agitation cycles for distributing reagents evenly and uniformly across the specimen. The systems can be implemented as a standalone device or as a component in a larger system for preparing and examining biological specimens.
    Type: Grant
    Filed: April 8, 2013
    Date of Patent: August 25, 2015
    Assignee: Roche Diagnostics Hematology, Inc.
    Inventors: Daniel Lapen, David Zahniser, Mark Licari, Brian J. McKeen, Eric D. Yeaton, Dennis Poole
  • Patent number: 9057672
    Abstract: Sample application systems can include an extraction mechanism to remove a sample from sample containers, a sample vessel disposed on a deployment mechanism, where the deployment mechanism is arranged to move the sample vessel to receive a sample, an extraction mechanism washing station to wash the extraction mechanism, a sample applicator to remove a portion of the sample in the sample vessel and apply it onto a sample carrier, where the deployment mechanism can move the sample vessel to a sample application position, a sample vessel washing station to wash the sample vessel, where the deployment mechanism can move the sample vessel to the sample vessel washing station, a sample applicator washing station to wash the sample applicator after the sample has been dispensed onto the sample carrier, and a fluid control system to control flow of a fluid provided to the extraction mechanism and the sample applicator.
    Type: Grant
    Filed: July 13, 2012
    Date of Patent: June 16, 2015
    Assignee: Roche Diagnostics Hematology, Inc.
    Inventors: Brian J. McKeen, Eric D. Yeaton, James L. Dowling
  • Patent number: 8454908
    Abstract: The systems and methods disclosed herein permit automated preparation of biological specimens for examination. The disclosed systems and methods provide fast, efficient, and highly uniform specimen processing using minimal quantities of fluids. The methods include at least a fixing phase for fixing a biological specimen to a substrate such as a microscope slide, a staining phase for staining the specimen, and a rinsing phase for rinsing the specimen. One or more of the fixing, staining, and rinsing phases include one or more agitation cycles for distributing reagents evenly and uniformly across the specimen. The systems can be implemented as a standalone device or as a component in a larger system for preparing and examining biological specimens.
    Type: Grant
    Filed: November 9, 2011
    Date of Patent: June 4, 2013
    Assignee: Constitution Medical, Inc.
    Inventors: Daniel Lapen, David Zahniser, Mark Licari, Brian J. McKeen, Eric D. Yeaton, Dennis Poole
  • Publication number: 20130019697
    Abstract: Sample application systems can include an extraction mechanism to remove a sample from sample containers, a sample vessel disposed on a deployment mechanism, where the deployment mechanism is arranged to move the sample vessel to receive a sample, an extraction mechanism washing station to wash the extraction mechanism, a sample applicator to remove a portion of the sample in the sample vessel and apply it onto a sample carrier, where the deployment mechanism can move the sample vessel to a sample application position, a sample vessel washing station to wash the sample vessel, where the deployment mechanism can move the sample vessel to the sample vessel washing station, a sample applicator washing station to wash the sample applicator after the sample has been dispensed onto the sample carrier, and a fluid control system to control flow of a fluid provided to the extraction mechanism and the sample applicator.
    Type: Application
    Filed: July 13, 2012
    Publication date: January 24, 2013
    Applicant: CONSTITUTION MEDICAL, INC.
    Inventors: Brian J. McKeen, Eric D. Yeaton, James L. Dowling
  • Publication number: 20130020175
    Abstract: Sample transport systems are described that move a sample carrier from one station to a next station in a sample processing systems. The systems include: a translating member; two or more sample carrier retaining devices attached to the translating member, wherein each of the two or more sample carrier retaining devices can include a retainer portion to temporarily retain one or more sample carriers; and a movement mechanism to move the translating member and the attached sample carrier retaining devices between a first position and a second position; wherein the sample carrier retaining devices are controlled and moved simultaneously to retain a sample carrier when the translating member reaches the first position and to release a sample carrier when the translating member reaches the second position to successively advance sample carriers in the sample processing systems.
    Type: Application
    Filed: July 13, 2012
    Publication date: January 24, 2013
    Applicant: CONSTITUTION MEDICAL, INC.
    Inventors: Brian J. McKeen, Eric D. Yeaton, James L. Dowling
  • Publication number: 20120149050
    Abstract: The systems and methods disclosed herein permit automated preparation of biological specimens for examination. The disclosed systems and methods provide fast, efficient, and highly uniform specimen processing using minimal quantities of fluids. The methods include at least a fixing phase for fixing a biological specimen to a substrate such as a microscope slide, a staining phase for staining the specimen, and a rinsing phase for rinsing the specimen. One or more of the fixing, staining, and rinsing phases include one or more agitation cycles for distributing reagents evenly and uniformly across the specimen. The systems can be implemented as a standalone device or as a component in a larger system for preparing and examining biological specimens.
    Type: Application
    Filed: November 9, 2011
    Publication date: June 14, 2012
    Applicant: CONSTITUTION MEDICAL, INC.
    Inventors: Daniel Lapen, David Zahniser, Mark Licari, Brian J. McKeen, Eric D. Yeaton, Dennis Poole
  • Patent number: 6844992
    Abstract: An opto-mechanical platform for supporting truncated optical elements having at least one substantially flat side surface is disclosed. In one particular exemplary embodiment, the opto-mechanical platform may be realized as an apparatus for supporting truncated optical elements having at least one substantially flat side surface. Such an apparatus may comprise a platform having a substantially flat surface area for supporting the substantially flat side surface of the truncated optical elements. Such an apparatus may also comprise at least one substantially vertical wall formed on at least a portion of the platform for providing mechanical rigidity to the platform.
    Type: Grant
    Filed: March 18, 2003
    Date of Patent: January 18, 2005
    Assignee: Confluent Photonics Corporation
    Inventors: Thomas A. Schaefer, Gregory G. Cappiello, Ninghui Zhu, Kurt E. Abdelmaseh, Evgueni V. Babenko, William J. Hubbard, Kevin J. McIntyre, Brian J. McKeen, Paul Ouellette, Andrew Radl, Dick Rolfe
  • Publication number: 20030179472
    Abstract: An opto-mechanical platform for supporting truncated optical elements having at least one substantially flat side surface is disclosed. In one particular exemplary embodiment, the opto-mechanical platform may be realized as an apparatus for supporting truncated optical elements having at least one substantially flat side surface. Such an apparatus may comprise a platform having a substantially flat surface area for supporting the substantially flat side surface of the truncated optical elements. Such an apparatus may also comprise at least one substantially vertical wall formed on at least a portion of the platform for providing mechanical rigidity to the platform.
    Type: Application
    Filed: March 18, 2003
    Publication date: September 25, 2003
    Inventors: Thomas A. Schaefer, Gregory G. Cappiello, Ninghui Zhu, Kurt E. Abdelmaseh, Evgueni V. Babenko, William J. Hubbard, Kevin J. McIntyre, Brian J. McKeen, Paul Ouellette, Andrew Radl, Dick Rolfe