Patents by Inventor Brian J. Staskawicz

Brian J. Staskawicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11891612
    Abstract: Provided herein is a plant comprising an exogenous polynucleotide encoding a JIM2 polypeptide. In some embodiments, the plants have enhanced resistance to at least one species of Xanthomonas.
    Type: Grant
    Filed: May 24, 2019
    Date of Patent: February 6, 2024
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Brian J. Staskawicz, Alexander Christiaan Schultink
  • Publication number: 20230002781
    Abstract: Disclosed herein are methods for identifying amino acid residues of NLRs that are likely involved in pathogen immunity. Also disclosed are methods for modifying plant immunity which comprise modifying (e.g., substituting, deleting, or adding an amino acid before or after) one or more of the amino acid residues that have been identified as being likely involved in pathogen immunity.
    Type: Application
    Filed: December 4, 2020
    Publication date: January 5, 2023
    Inventors: Ksenia Vladimirovna Krasileva, Daniil M. Prigozhin, Brian J. Staskawicz, Furong Liu
  • Patent number: 11236355
    Abstract: Provided herein is a non-Nicotiana transgenic plant comprising an exogenous polynucleotide encoding Nicotiana benthamiana Roq1 or a variant thereof. These plants have enhanced resistance to at least one species of Xanthomonas, Pseudomonas, Ralstonia, and/or another pathogen containing a homolog of XopQ whose recognition is mediated by Roq1.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: February 1, 2022
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Brian J. Staskawicz, Alexander Christiaan Schultink
  • Publication number: 20210310019
    Abstract: Provided herein is a plant comprising an exogenous polynucleotide encoding a JIM2 polypeptide. In some embodiments, the plants have enhanced resistance to at least one species of Xanthomonas.
    Type: Application
    Filed: May 24, 2019
    Publication date: October 7, 2021
    Inventors: Brian J. STASKAWICZ, Alexander Christiaan SCHULTINK
  • Publication number: 20210130843
    Abstract: Provided herein is a non-Nicotiana transgenic plant comprising an exogenous polynucleotide encoding Nicotiana benthamiana Roq1 or a variant thereof. These plants have enhanced resistance to at least one species of Xanthomonas, Pseudomonas, Ralstonia, and/or another pathogen containing a homolog of XopQ whose recognition is mediated by Roq1.
    Type: Application
    Filed: August 21, 2018
    Publication date: May 6, 2021
    Inventors: Brian J. STASKAWICZ, Alexander Christiaan SCHULTINK
  • Publication number: 20210071193
    Abstract: The invention provides plants and seeds with enhanced resistance to plant disease caused by plant pathogens, particularly bacterial plant pathogens, and methods for producing such plants and seeds. The plants and seeds comprise mutated alleles of the Bs5 gene and/or Bs5-like gene that are capable of conferring to plants comprising the alleles enhanced resistance to plant pathogens. The present invention further provides methods of using the plants and seeds in agricultural production to limit plant diseases caused by plant pathogens.
    Type: Application
    Filed: July 10, 2020
    Publication date: March 11, 2021
    Inventors: DOUGLAS DAHLBECK, ARTURO ORTEGA, ALEX SCHULTINK, BRIAN J. STASKAWICZ
  • Publication number: 20170114360
    Abstract: The invention provides seed and plants of tomato comprising transgenic event Bs2-X5 and progeny thereof comprising this transgenic event and uses of such seeds and plants in the production of tomato fruit. The invention thus relates to non-hybrid and hybrid plants, seeds, and tissue cultures of tomato comprising transgenic event Bs2-X5, and to methods for producing a tomato plant produced by crossing such plants with themselves or with another tomato plant, such as a plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants, including the fruit and gametes of such plants.
    Type: Application
    Filed: January 6, 2017
    Publication date: April 27, 2017
    Inventors: Brian J. Staskawicz, Douglas Dahlbeck
  • Patent number: 9580726
    Abstract: The invention provides seed and plants of tomato comprising transgenic event Bs2-X5 and progeny thereof comprising this transgenic event and uses of such seeds and plants in the production of tomato fruit. The invention thus relates to non-hybrid and hybrid plants, seeds, and tissue cultures of tomato comprising transgenic event Bs2-X5, and to methods for producing a tomato plant produced by crossing such plants with themselves or with another tomato plant, such as a plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants, including the fruit and gametes of such plants.
    Type: Grant
    Filed: July 31, 2014
    Date of Patent: February 28, 2017
    Assignee: The Regents of the University of California
    Inventors: Brian J. Staskawicz, Douglas Dahlbeck
  • Publication number: 20150040264
    Abstract: The invention provides seed and plants of tomato comprising transgenic event Bs2-X5 and progeny thereof comprising this transgenic event and uses of such seeds and plants in the production of tomato fruit. The invention thus relates to non-hybrid and hybrid plants, seeds, and tissue cultures of tomato comprising transgenic event Bs2-X5, and to methods for producing a tomato plant produced by crossing such plants with themselves or with another tomato plant, such as a plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants, including the fruit and gametes of such plants.
    Type: Application
    Filed: July 31, 2014
    Publication date: February 5, 2015
    Inventors: Brian J. Staskawicz, Douglas Dahlbeck
  • Publication number: 20140137292
    Abstract: Methods and compositions for making citrus plants with enhanced resistance to Asiatic citrus canker (ACC) and other forms of citrus canker caused by Xanthomonas are provided. The methods involve transforming citrus plant cells with polynucleotide constructs comprising a promoter operably linked to nucleotide sequence that encodes a protein that is capable of triggering cell death in a citrus plant. The promoters of the invention are inducible by one or more Xanthomonas strains that cause citrus canker. Isolated nucleic acid molecules and expression cassettes comprising such polynucleotide constructs and promoters are further provided. Citrus plants with enhanced resistance to citrus canker are also provided.
    Type: Application
    Filed: January 12, 2012
    Publication date: May 15, 2014
    Applicants: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION INC., TWO BLADES FOUNDATION
    Inventors: Jeffrey B. Jones, Thomas Lahaye, Brian J. Staskawicz
  • Publication number: 20080085835
    Abstract: Disclosed is substantially pure DNA encoding an Arabidopsis thaliana Rps2 polypeptide, substantially pure Rps2 polyneptide; and methods of using such DNA to express the Rps2 polypeptide in plant cells and whole plants to provide, in transgenic plants, disease resistance to pathogens. Also disclosed are conserved regions characteristic of the RPS family and primers and probes for the identification and isolation of additional RPS disease-resistance genes.
    Type: Application
    Filed: September 29, 2006
    Publication date: April 10, 2008
    Inventors: Frederick M. AUSUBEL, Brian J. Staskawicz, Andrew F. Bent, Douglas Dahlbeck, Fumiaki Katagiri, Barbara N. Kunkel, Michael Nicholas, Guo-Liang Yu, Barbara Baker, Jeffrey Ellis, John Salmeron
  • Patent number: 7179601
    Abstract: The invention relates to a method of identifying a plant disease-resistance gene that includes the steps of (a) providing a plant tissue sample; (b)introducing by biolistic transformation into the plant tissue sample a candidate plant disease-resistance gene; (c) expressing the candidate plant disease-resistance gene within the plant tissue sample; and (d) determining whether the plant tissue sample exhibits a disease-resistance response, whereby a response identifies a plant disease-resistance gene.
    Type: Grant
    Filed: July 2, 2003
    Date of Patent: February 20, 2007
    Inventors: Frederick M. Ausubel, Brian J. Staskawicz, Andrew F. Bent, Douglas Dahlbeck, Fumiaki Katagiri, Barbara N. Kunkel, Michael Nicholas Mindrinos, Guo-Liang Yu, Barbara Baker, Jeffrey Ellis, John Salmeron
  • Publication number: 20040172673
    Abstract: Disclosed is substantially pure DNA encoding an Arabidopsis thaliana Rps2 polypeptide; substantially pure Rps2 polypeptide; and methods of using such DNA to express the Rps2 polypeptide in plant cells and whole plants to provide, in transgenic plants, disease resistance to pathogens. Also disclosed are conserved regions characteristic of the RPS family and primers and probes for the identification and isolation of additional RPS disease-resistance genes.
    Type: Application
    Filed: July 2, 2003
    Publication date: September 2, 2004
    Inventors: Frederick M. Ausubel, Brian J. Staskawicz, Andrew F. Bent, Douglas Dahlbeck, Fumiaki Katagiri, Barbara N. Kunkel, Michael Nicholas Mindrinos, Guo-Liang Yu, Barbara Baker, Jeffrey Ellis, John Salmeron
  • Patent number: 6762285
    Abstract: Bs2 resistance proteins that confer resistance to the plant pathogen Xanthomonas campestris are disclosed. These proteins may be expressed in transgenic plants that are otherwise susceptible to infection by this bacterium in order to enhance resistance.
    Type: Grant
    Filed: May 24, 2001
    Date of Patent: July 13, 2004
    Assignee: The Regents of the University of California
    Inventors: Brian J. Staskawicz, Douglas Dehlbeck, Thomas H. Tai
  • Publication number: 20040088756
    Abstract: The invention relates to a method of identifying a plant disease-resistance gene that includes the steps of (a) providing a plant tissue sample, (b)introducing by biolistic transformation into the plant tissue sample a candidate plant disease-resistance gene; (c) expressing the candidate plant disease-resistance gene within the plant tissue sample; and (d) determining whether the plant tissue sample exhibits a disease-resistance response, whereby a response identifies a plant disease-resistance gene.
    Type: Application
    Filed: July 2, 2003
    Publication date: May 6, 2004
    Inventors: Frederick M. Ausubel, Brian J. Staskawicz, Andrew F. Bent, Douglas Dahlbeck, Fumiaki Katagiri, Barbara N. Kunkel, Michael Nicholas Mindrinos, Guo-Liang Yu, Barbara Baker, Jeffrey Ellis, John Salmeron
  • Publication number: 20020147324
    Abstract: Disclosed is substantially pure DNA encoding an Arabidopsis thaliana Rps2 polypeptide; substantially pure Rps2 polypeptide; and methods of using such DNA to express the Rps2 polypeptide in plant cells and whole plants to provide, in transgenic plants, disease resistance to pathogens. Also disclosed are conserved regions characteristic of the RPS family and primers and probes for the identification and isolation of additional RPS disease-resistance genes.
    Type: Application
    Filed: May 29, 2001
    Publication date: October 10, 2002
    Inventors: Frederick M. Ausubel, Brian J. Staskawicz, Andrew F. Bent, Douglas Dahlbeck, Fumiaki Katagiri, Barbara N. Kunkel, Michael Nicholas Mindrinos, Guo-Liang Yu, Barbara Baker, Jeffrey Ellis, John Salmeron
  • Publication number: 20020012981
    Abstract: Nucleic acid molecules (cDNAs and genes) that confer resistance to the plant pathogen Xanthomonas campestris are disclosed. These molecules may be introduced into plants that are otherwise susceptible to infection by this bacterium in order to enhance resistance.
    Type: Application
    Filed: May 24, 2001
    Publication date: January 31, 2002
    Inventors: Brian J. Staskawicz, Douglas Dehlbeck, Thomas H. Tai
  • Patent number: 6262248
    Abstract: Disclosed is substantially pure DNA encoding an Arabidopsis thaliana Rps2 polypeptide; substantially pure Rps2 polypeptide; and methods of using such DNA to express the Rps2 polypeptide in plant cells and whole plants to provide, in transgenic plants, disease resistance to pathogens. Also disclosed are conserved regions characteristic of the RPS family and primers and probes for the identification and isolation of additional RPS disease-resistance genes.
    Type: Grant
    Filed: April 28, 1999
    Date of Patent: July 17, 2001
    Assignees: Massachusetts General Hospital Corporation, The United States of America as represented by the Secretary of Agriculture, Commonwealth Scientific and Industrial Research Organization, The Regents of the University of California
    Inventors: Frederick M. Ausubel, Brian J. Staskawicz, Andrew F. Bent, Douglas Dahlbeck, Fumiaki Katagiri, Barbara N. Kunkel, Michael Nicholas Mindrinos, Guo-Liang Yu, Barbara Baker, Jeffrey Ellis, John Salmeron
  • Patent number: 6262343
    Abstract: Nucleic acid molecules (cDNAs and genes) that confer resistance to the plant pathogen Xanthomonas campestris are disclosed. These molecules may be introduced into plants that are otherwise susceptible to infection by this bacterium in order to enhance resistance.
    Type: Grant
    Filed: July 23, 1999
    Date of Patent: July 17, 2001
    Assignee: The Regents of the University of California
    Inventors: Brian J. Staskawicz, Douglas Dahlbeck, Thomas H. Tai
  • Patent number: 6127607
    Abstract: Disclosed is a new plant resistance gene family, the members of which encode plant resistance polypeptides having P-loop and LRR structural motifs. Also disclosed are substantially pure plant DNAs encoding such polypeptides. The invention further involves transgenic plants and transformed host cells that express these DNAs and exhibit enhanced disease resistance to plant pathogens.
    Type: Grant
    Filed: April 29, 1997
    Date of Patent: October 3, 2000
    Assignees: The General Hospital Corporation, The Regents of the University of California
    Inventors: Frederick Michael Ausubel, Brian J. Staskawicz, Andrew F. Bent, Douglas Dahlbeck, Fumiaki Katagiri, Barbara N. Kunkel, Michael Nicholas Mindrinos, Guo-Liang Yu