Patents by Inventor Brian James MARQUARDT
Brian James MARQUARDT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11029245Abstract: A flow cell device including a spherical optical element is disclosed. The spherical lens can be sealed to the body of the flow cell device in a manner that provides external optical access to a fluid in an analysis region of a flow path through the flow cell device. The seal can be provided by an elastomer, a polymer, or a deformable metal. The disposition of the spherical lens to the flow path enables in situ optical analysis of the fluid. An optical analysis device can be removably connected to the flow cell device to provide the optical analysis. In some embodiments the optical analysis device is a portable Raman spectrometer. The flow cell device can provide a supplementary interrogation interface, and/or an on board sensor device(s) to enable multivariate analysis and/or advanced triggering.Type: GrantFiled: June 26, 2020Date of Patent: June 8, 2021Assignee: MarqMetrix, Inc.Inventors: Giora Proskurowski, Brian James Marquardt
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Publication number: 20200393360Abstract: A flow cell device including a spherical optical element is disclosed. The spherical lens can be sealed to the body of the flow cell device in a manner that provides external optical access to a fluid in an analysis region of a flow path through the flow cell device. The seal can be provided by an elastomer, a polymer, or a deformable metal. The disposition of the spherical lens to the flow path enables in situ optical analysis of the fluid. An optical analysis device can be removably connected to the flow cell device to provide the optical analysis. In some embodiments the optical analysis device is a portable Raman spectrometer. The flow cell device can provide a supplementary interrogation interface, and/or an on board sensor device(s) to enable multivariate analysis and/or advanced triggering.Type: ApplicationFiled: June 26, 2020Publication date: December 17, 2020Inventors: Giora Proskurowski, Brian James Marquardt
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Patent number: 10697885Abstract: A flow cell device including a spherical optical element is disclosed. The spherical lens can be sealed to the body of the flow cell device in a manner that provides external optical access to a fluid in an analysis region of a flow path through the flow cell device. The seal can be provided by an elastomer, a polymer, or a deformable metal. The disposition of the spherical lens to the flow path enables in situ optical analysis of the fluid. An optical analysis device can be removably connected to the flow cell device to provide the optical analysis. In some embodiments the optical analysis device is a portable Raman spectrometer. The flow cell device can provide a supplementary interrogation interface, and/or an on board sensor device(s) to enable multivariate analysis and/or advanced triggering.Type: GrantFiled: February 15, 2019Date of Patent: June 30, 2020Assignee: MarqMetrix, Inc.Inventors: Giora Proskurowski, Brian James Marquardt
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Patent number: 10656011Abstract: An enclosed benchtop analytical device, as well as systems, processes, and techniques related thereto are disclosed. A benchtop analytical device can include an enclosure enclosing a probe and a sample. A compliance component can determine satisfaction of one or more compliance rules, such as a compliance rule relating to an enclosure being in an operable configuration based on a lid of the enclosure being closed. If the compliance rule(s) is determined to be satisfied, the compliance component may enable the release of optical energy for interrogation of the sample via the probe. In some embodiments, the enclosure can enclose a sample plate that can be used to conveniently and accurately retain a sample in a suitable position within the enclosure.Type: GrantFiled: September 9, 2019Date of Patent: May 19, 2020Assignee: MarqMetrix, Inc.Inventors: Brian James Marquardt, John Scott Van Vuren
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Patent number: 10634616Abstract: An optical immersion probe assembly with an alignment mechanism is described. The alignment mechanism ensures that proper alignment is achieved between an optical fiber head and an optical immersion probe whenever the optical immersion probe is coupled to the optical fiber head. The alignment mechanism may include a notch defined in a portion of a first annular end surface of the optical fiber head, and a projection on a periphery of the optical immersion probe. The projection on the probe may be positioned a distance from a second annular end surface of the optical immersion probe, and sized to be received within the notch of the optical fiber head. Also described herein are techniques and processes for manufacturing the components of an optical immersion probe assembly, and for assembling the optical immersion probe assembly.Type: GrantFiled: December 26, 2018Date of Patent: April 28, 2020Assignee: MarqMetrix, Inc.Inventors: Brian James Marquardt, Giora Proskurowski, Alex McNeill
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Publication number: 20200003617Abstract: An enclosed benchtop analytical device, as well as systems, processes, and techniques related thereto are disclosed. A benchtop analytical device can include an enclosure enclosing a probe and a sample. A compliance component can determine satisfaction of one or more compliance rules, such as a compliance rule relating to an enclosure being in an operable configuration based on a lid of the enclosure being closed.. If the compliance rule(s) is determined to be satisfied, the compliance component may enable the release of optical energy for interrogation of the sample via the probe. In some embodiments, the enclosure can enclose a sample plate that can be used to conveniently and accurately retain a sample in a suitable position within the enclosure.Type: ApplicationFiled: September 9, 2019Publication date: January 2, 2020Inventors: Brian James Marquardt, John Scott Van Vuren
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Patent number: 10408675Abstract: An enclosed benchtop analytical device, as well as systems, processes, and techniques related thereto are disclosed. A benchtop analytical device can include an enclosure enclosing a probe and a sample. A compliance component can determine satisfaction of one or more compliance rules, such as a compliance rule relating to an enclosure being in an operable configuration based on a lid of the enclosure being closed. If the compliance rule(s) is determined to be satisfied, the compliance component may enable the release of optical energy for interrogation of the sample via the probe. In some embodiments, the enclosure can enclose a sample plate that can be used to conveniently and accurately retain a sample in a suitable position within the enclosure.Type: GrantFiled: February 15, 2018Date of Patent: September 10, 2019Assignee: MarqMetrix, Inc.Inventors: Brian James Marquardt, John Scott Van Vuren
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Publication number: 20190178786Abstract: A flow cell device including a spherical optical element is disclosed. The spherical lens can be sealed to the body of the flow cell device in a manner that provides external optical access to a fluid in an analysis region of a flow path through the flow cell device. The seal can be provided by an elastomer, a polymer, or a deformable metal. The disposition of the spherical lens to the flow path enables in situ optical analysis of the fluid. An optical analysis device can be removably connected to the flow cell device to provide the optical analysis. In some embodiments the optical analysis device is a portable Raman spectrometer. The flow cell device can provide a supplementary interrogation interface, and/or an on board sensor device(s) to enable multivariate analysis and/or advanced triggering.Type: ApplicationFiled: February 15, 2019Publication date: June 13, 2019Inventors: Giora Proskurowski, Brian James Marquardt
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Patent number: 10309832Abstract: Portable analytical equipment, systems, methods, and techniques related thereto is disclosed. Portable analytical equipment can comprise a controller and a probe. The probe can interrogate a sample and receive a response to the interrogation. The controller can select and/or initiate an analysis related to interrogating the sample via the probe. The analysis can be selected from a portfolio of analyses stored on the controller. The controller can analyze the response to the interrogation based on reference data stored on the controller. The controller can determine an indication based on the analyzing the response for presentation via a low-power interface, which can comprise an LED or electrophoretic element. The controller can further be connected to an external device, e.g., a smartphone or remote PC, to present collected data and the analyzing of the response to the interrogation. The disclosed subject matter can be employed in hand-held analytical equipment, e.g., a hand-held Raman spectrometer.Type: GrantFiled: August 18, 2017Date of Patent: June 4, 2019Assignee: MarqMetrix Inc.Inventors: Brian James Marquardt, John Scott Van Vuren
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Patent number: 10209176Abstract: A flow cell device including a spherical optical element is disclosed. The spherical lens can be sealed to the body of the flow cell device in a manner that provides external optical access to a fluid in an analysis region of a flow path through the flow cell device. The seal can be provided by an elastomer, a polymer, or a deformable metal. The disposition of the spherical lens to the flow path enables in situ optical analysis of the fluid. An optical analysis device can be removably connected to the flow cell device to provide the optical analysis. In some embodiments the optical analysis device is a portable Raman spectrometer. The flow cell device can provide a supplementary interrogation interface, and/or an on board sensor device(s) to enable multivariate analysis and/or advanced triggering.Type: GrantFiled: February 28, 2018Date of Patent: February 19, 2019Assignee: MarqMetrix, Inc.Inventors: Giora Proskurowski, Brian James Marquardt
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Publication number: 20180246031Abstract: A flow cell device including a spherical optical element is disclosed. The spherical lens can be sealed to the body of the flow cell device in a manner that provides external optical access to a fluid in an analysis region of a flow path through the flow cell device. The seal can be provided by an elastomer, a polymer, or a deformable metal. The disposition of the spherical lens to the flow path enables in situ optical analysis of the fluid. An optical analysis device can be removably connected to the flow cell device to provide the optical analysis. In some embodiments the optical analysis device is a portable Raman spectrometer. The flow cell device can provide a supplementary interrogation interface, and/or an on board sensor device(s) to enable multivariate analysis and/or advanced triggering.Type: ApplicationFiled: February 28, 2018Publication date: August 30, 2018Inventors: Giora Proskurowski, Brian James Marquardt
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Publication number: 20180231415Abstract: An enclosed benchtop analytical device, as well as systems, processes, and techniques related thereto are disclosed. A benchtop analytical device can include an enclosure enclosing a probe and a sample. A compliance component can determine satisfaction of one or more compliance rules, such as a compliance rule relating to an enclosure being in an operable configuration based on a lid of the enclosure being closed. If the compliance rule(s) is determined to be satisfied, the compliance component may enable the release of optical energy for interrogation of the sample via the probe. In some embodiments, the enclosure can enclose a sample plate that can be used to conveniently and accurately retain a sample in a suitable position within the enclosure.Type: ApplicationFiled: February 15, 2018Publication date: August 16, 2018Inventors: Brian James Marquardt, John Scott Van Vuren
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Patent number: 9958324Abstract: An enclosed benchtop Raman spectrometry device, systems, methods, and techniques related thereto are disclosed. A benchtop Raman spectrometer can comprise an enclosure enclosing a probe and sample. In an embodiment, a compliance component can determine concurrent satisfaction of a group of compliance rules. The compliance rules can relate to contact between the probe and sample, environmental conditions within the enclosure, illumination conditions within the enclosure, an operation state of a viewport allowing direct viewing of a sample-probe interface, etc. While concurrent satisfaction is determined, the release of optical energy for interrogation of the sample via the probe can be enabled. In an embodiment, the probe can comprise a spherical optical element, e.g., a BallProbeĀ®, which can be brought into contact with the sample to perform Raman spectroscopy.Type: GrantFiled: February 15, 2017Date of Patent: May 1, 2018Assignee: MarqMetrix Inc.Inventors: Brian James Marquardt, John Scott Van Vuren, Giora Proskurowski
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Publication number: 20170350762Abstract: Portable analytical equipment, systems, methods, and techniques related thereto is disclosed. Portable analytical equipment can comprise a controller and a probe. The probe can interrogate a sample and receive a response to the interrogation. The controller can select and/or initiate an analysis related to interrogating the sample via the probe. The analysis can be selected from a portfolio of analyses stored on the controller. The controller can analyze the response to the interrogation based on reference data stored on the controller. The controller can determine an indication based on the analyzing the response for presentation via a low-power interface, which can comprise an LED or electrophoretic element. The controller can further be connected to an external device, e.g., a smartphone or remote PC, to present collected data and the analyzing of the response to the interrogation. The disclosed subject matter can be employed in hand-held analytical equipment, e.g., a hand-held Raman spectrometer.Type: ApplicationFiled: August 18, 2017Publication date: December 7, 2017Inventors: Brian James MARQUARDT, John Scott VAN VUREN
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Patent number: 9752935Abstract: Portable analytical equipment, systems, methods, and techniques related thereto is disclosed. Portable analytical equipment can comprise a controller and a probe. The probe can interrogate a sample and receive a response to the interrogation. The controller can select and/or initiate an analysis related to interrogating the sample via the probe. The analysis can be selected from a portfolio of analyses stored on the controller. The controller can analyze the response to the interrogation based on reference data stored on the controller. The controller can determine an indication based on the analyzing the response for presentation via a low-power interface, which can comprise an LED or electrophoretic element. The controller can further be connected to an external device, e.g., a smartphone or remote PC, to present collected data and the analyzing of the response to the interrogation. The disclosed subject matter can be employed in hand-held analytical equipment, e.g., a hand-held Raman spectrometer.Type: GrantFiled: August 25, 2015Date of Patent: September 5, 2017Assignee: MARQMETRIX, INC.Inventors: Brian James Marquardt, John Scott Van Vuren
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Publication number: 20160161705Abstract: Examples embodiments of a removable optical assembly are disclosed. A removable optical assembly can be removably attached to a probe of an optical analytical instrument. The removable optical assembly can comprise a spherical optical element. An embodiment of the removable optical assembly can allow contact interrogation of a sample. In some embodiments, the removable optical assembly can comprise an internal optical element. In other embodiments, the removable optical assembly can comprise an external optical element. Manufacture of the removable optical assembly can comprise a monolithic embodiment or an assembled embodiment comprising a plurality of subassemblies. Embodiments of the removable optical assembly can be conical, cylindrical or planar is shape. The removable optical assembly can, in some embodiments, be consumable and/or disposable.Type: ApplicationFiled: December 2, 2015Publication date: June 9, 2016Inventors: Brian James Marquardt, John Scott Van Vuren
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Publication number: 20160061663Abstract: Portable analytical equipment, systems, methods, and techniques related thereto is disclosed. Portable analytical equipment can comprise a controller and a probe. The probe can interrogate a sample and receive a response to the interrogation. The controller can select and/or initiate an analysis related to interrogating the sample via the probe. The analysis can be selected from a portfolio of analyses stored on the controller. The controller can analyze the response to the interrogation based on reference data stored on the controller. The controller can determine an indication based on the analyzing the response for presentation via a low-power interface, which can comprise an LED or electrophoretic element. The controller can further be connected to an external device, e.g., a smartphone or remote PC, to present collected data and the analyzing of the response to the interrogation. The disclosed subject matter can be employed in hand-held analytical equipment, e.g., a hand-held Raman spectrometer.Type: ApplicationFiled: August 25, 2015Publication date: March 3, 2016Inventors: Brian James MARQUARDT, John Scott VAN VUREN