Patents by Inventor Brian Jamieson
Brian Jamieson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 10285605Abstract: In certain embodiments, a neural probe comprises a substrate comprising elongated shanks for penetrating neural tissue, each comprising a proximal end and a distal end; at least one optical source integral to the neural probe for illuminating the neural tissue; and microelectrodes located proximate the distal end of the elongated shanks for monitoring neuronal activity. In certain embodiments, a method of monitoring neuronal activity comprises implanting the neural probe into a test subject such that the elongated shanks protrude into neural tissue of the test subject; illuminating the neural tissue with the at least one optical source; and measuring neuronal activity in response to illuminating the neural tissue. In certain embodiments, a device comprises a semiconductor chip; at least one optical source integral to the semiconductor chip; and sensor elements integral to the semiconductor chip for collecting data responsive to light emitted from the at least one optical source.Type: GrantFiled: September 27, 2017Date of Patent: May 14, 2019Assignee: DIAGNOSTIC BIOCHIPS, INC.Inventors: Brian Jamieson, Jennette Mateo
-
Patent number: 10188304Abstract: In certain embodiments, a neural probe comprises a substrate comprising elongated shanks for penetrating neural tissue, each comprising a proximal end and a distal end; at least one optical source integral to the neural probe for illuminating the neural tissue; and microelectrodes located proximate the distal end of the elongated shanks for monitoring neuronal activity. In certain embodiments, a method of monitoring neuronal activity comprises implanting the neural probe into a test subject such that the elongated shanks protrude into neural tissue of the test subject; illuminating the neural tissue with the at least one optical source; and measuring neuronal activity in response to illuminating the neural tissue. In certain embodiments, a device comprises a semiconductor chip; at least one optical source integral to the semiconductor chip; and sensor elements integral to the semiconductor chip for collecting data responsive to light emitted from the at least one optical source.Type: GrantFiled: July 24, 2012Date of Patent: January 29, 2019Assignee: Diagnostic Biochips, Inc.Inventors: Brian Jamieson, Jennette Mateo
-
Publication number: 20180236444Abstract: A microfluidic chip having integrated heaters and a method for manufacturing the microfluidic chip is provided. Specifically, the microfluidic chip comprises a first substrate having a microchannel formed therein. The second substrate is bonded to the first substrate to encapsulate the microchannel. An integrated heating element, that is hermetically sealed and electrically isolated from the microchannel, is formed on the top surface the second substrate after the first and second substrates are bonded together. A biological reaction can be performed in the microchannel of the microfluidic chip while the fluid in the microchannel is heated by electrical current passing through the integrated heating element.Type: ApplicationFiled: July 2, 2015Publication date: August 23, 2018Applicant: Canon U.S. Life Sciences, Inc.Inventors: Kenton C. Hasson, Andrea Pais, Brian Jamieson
-
Patent number: 9983047Abstract: A system and method for monitoring a level of material in a storage bin, including a gear train, a gear train shaft rotatably coupled to the gear train, a drive shaft, a coupling system to couple the gear train shaft to the drive shaft, a paddle coupled to the drive shaft to rotate in unison therewith, the paddle configured to engage a material in the storage bin when the level of material reaches a threshold level, and a stepper motor. A controller may be communicatively coupled to the stepper motor wherein the controller is configured to monitor the running state and the stall state of the stepper motor.Type: GrantFiled: September 24, 2014Date of Patent: May 29, 2018Assignee: VENTURE MEASUREMENT COMPANY, LLCInventors: Michael Starinki, Christopher Hampton, Brian Jamieson
-
Patent number: 9883826Abstract: Certain embodiments comprise an implantable probe for rapid measurement of multiple neurochemicals on the cellular scale in the brain. Rapid detection of multiple chemicals in vivo (animal or humans) may provide an improved understanding of acute changes in neurochemicals that occur over several seconds. The neurotransmitter chemical sensing platform may provide for continuous in vivo sensing in trials of psychoactive drugs in the laboratory animal market. The high spatial resolution of the probe may allow for chemical detection around small groups of neurons, which may help to isolate the endogenous activity of different neuron types due to disease states. Neurochemical detection may also be used to measure tissue response to exogenous stimuli, such as pharmacodynamics of drugs. The high temporal and spatial resolutions and multi-neurochemical sensing of the probe may allow for detailed studies on in vivo brain response to both endogenous and exogenous stimuli.Type: GrantFiled: July 15, 2013Date of Patent: February 6, 2018Assignee: DIAGNOSTIC BIOCHIPS, INC.Inventors: Brian Jamieson, Mary Emma Gorham Bigelow
-
Publication number: 20180028119Abstract: In certain embodiments, a neural probe comprises a substrate comprising elongated shanks for penetrating neural tissue, each comprising a proximal end and a distal end; at least one optical source integral to the neural probe for illuminating the neural tissue; and microelectrodes located proximate the distal end of the elongated shanks for monitoring neuronal activity. In certain embodiments, a method of monitoring neuronal activity comprises implanting the neural probe into a test subject such that the elongated shanks protrude into neural tissue of the test subject; illuminating the neural tissue with the at least one optical source; and measuring neuronal activity in response to illuminating the neural tissue. In certain embodiments, a device comprises a semiconductor chip; at least one optical source integral to the semiconductor chip; and sensor elements integral to the semiconductor chip for collecting data responsive to light emitted from the at least one optical source.Type: ApplicationFiled: September 27, 2017Publication date: February 1, 2018Applicant: DIAGNOSTIC BIOCHIPS, INC.Inventors: Brian Jamieson, Jennette Mateo
-
Patent number: 9801559Abstract: In certain embodiments, a neural probe comprises a substrate comprising elongated shanks for penetrating neural tissue, each comprising a proximal end and a distal end; at least one optical source integral to the neural probe for illuminating the neural tissue; and microelectrodes located proximate the distal end of the elongated shanks for monitoring neuronal activity. In certain embodiments, a method of monitoring neuronal activity comprises implanting the neural probe into a test subject such that the elongated shanks protrude into neural tissue of the test subject; illuminating the neural tissue with the at least one optical source; and measuring neuronal activity in response to illuminating the neural tissue. In certain embodiments, a device comprises a semiconductor chip; at least one optical source integral to the semiconductor chip; and sensor elements integral to the semiconductor chip for collecting data responsive to light emitted from the at least one optical source.Type: GrantFiled: July 25, 2011Date of Patent: October 31, 2017Assignee: DIAGNOSTIC BIOCHIPS, INC.Inventors: Brian Jamieson, Jennette Mateo
-
Publication number: 20170258404Abstract: Provided herein is a coated biosensor and a method of preserving a coated biosensor to protect it during implantation into the brain or other tissues by coating the biosensor with a protective coating.Type: ApplicationFiled: November 25, 2015Publication date: September 14, 2017Applicant: DIAGNOSTIC BIOCHIPS, INC.Inventors: Emma Bigelow, Brian Jamieson
-
Publication number: 20170020422Abstract: The specification and drawings show an embodiment of the present invention in the form of a device comprising one or more biosensors either placed or imbedded in a catheter, needle or combination of the two. The catheter or needle comprises exclusionary slits upstream of the biosensor(s), angled so that fluid flows in through the slits and down past the biosensors. The wires connecting the biosensors to external monitoring and/or analytical apparatus are wired through the catheter or needle material. Also provided herein are methods for detection of small molecules using the device described herein.Type: ApplicationFiled: April 8, 2015Publication date: January 26, 2017Applicant: DIAGNOSTIC BIOCHIPS, INC.Inventors: Emma Bigelow, Rohan Pais, Rob Collins, Brian Jamieson
-
Publication number: 20160238432Abstract: A system and method for monitoring a level of material in a storage bin, including a gear train, a gear train shaft rotatably coupled to the gear train, a drive shaft, a coupling system to couple the gear train shaft to the drive shaft, a paddle coupled to the drive shaft to rotate in unison therewith, the paddle configured to engage a material in the storage bin when the level of material reaches a threshold level, and a stepper motor. A controller may be communicatively coupled to the stepper motor wherein the controller is configured to monitor the running state and the stall state of the stepper motor.Type: ApplicationFiled: September 24, 2014Publication date: August 18, 2016Applicants: Venture Measurement, Venture Measurement, Venture MeasurementInventors: Michael Starinki, Christopher Hampton, Brian Jamieson
-
Publication number: 20160195509Abstract: This invention relates to analyzing elements, including metals in mechanical systems. The invention therefore allows for detecting wear elements, such as metals, for example, in lubricants to determine whether the mechanical system is deteriorating, or even approaching failure. The invention relates to an integrated micro-electromechanical (MEMS) apparatus, and methods for using this apparatus.Type: ApplicationFiled: January 6, 2016Publication date: July 7, 2016Inventors: Brian JAMIESON, Michael DICKERSON, Steven VAN FLEET
-
Publication number: 20150306386Abstract: Various systems and methods related to the design and manufacturing of wearable patches for long-term, controlled stimulation of highly-localized regions on the skin of a wearer, including for the practice of acupuncture, are disclosed and claimed.Type: ApplicationFiled: April 24, 2015Publication date: October 29, 2015Inventors: Meredith Alpert, Brian Jamieson
-
Publication number: 20150164397Abstract: Certain embodiments comprise an implantable probe for rapid measurement of multiple neurochemicals on the celluar scale in the brain. Rapid detection of multiple chemicals in vivo (animal or humans) may provide an improved understanding of acute changes in neurochemicals that occur over several seconds. The neurotransmitter chemical sensing platform may provide for continuous in vivo sensing in trials of psychoactive drugs in the laboratory animal market. The high spatial resolution of the probe may allow for chemical detection around small groups of neurons, which may help to isolate the endogenous activity of different neuron types due to disease states. Neurochemical detection may also be used to measure tissue response to exogenous stimuli, such as pharmacodynamics of drugs. The high temporal and spatial resolutions and multi-neurochemical sensing of the probe may allow for detailed studies on in vivo brain response to both endogenous and exogenous stimuli.Type: ApplicationFiled: July 15, 2013Publication date: June 18, 2015Inventors: Brian Jamieson, Mary Emma Gorham Bigelow
-
Publication number: 20140309503Abstract: Methods, systems, and apparatuses for an ingestible sensor device are described. The ingestible sensor devices may be swallowed by an animal to diagnose one or more conditions of the animal. The ingestible sensor device may include a sensor configured to receive a stimulus inside the gastrointestinal tract of an animal, wherein the sensor is configured to output a signal having a characteristic proportional to the received stimulus. The ingestible sensor device may further include a communications module that transmits a signal modulated with the sensor output signal and a housing configured to have a size that is swallowable, wherein the housing substantially encloses the sensor and communications module.Type: ApplicationFiled: November 15, 2013Publication date: October 16, 2014Applicant: INNURVATION, INC.Inventors: Michael R. Arneson, William R. Bandy, Kevin J. Powell, Brian Jamieson
-
Publication number: 20140200431Abstract: In certain embodiments, a neural probe comprises a substrate comprising elongated shanks for penetrating neural tissue, each comprising a proximal end and a distal end; at least one optical source integral to the neural probe for illuminating the neural tissue; and microelectrodes located proximate the distal end of the elongated shanks for monitoring neuronal activity. In certain embodiments, a method of monitoring neuronal activity comprises implanting the neural probe into a test subject such that the elongated shanks protrude into neural tissue of the test subject; illuminating the neural tissue with the at least one optical source; and measuring neuronal activity in response to illuminating the neural tissue. In certain embodiments, a device comprises a semiconductor chip; at least one optical source integral to the semiconductor chip; and sensor elements integral to the semiconductor chip for collecting data responsive to light emitted from the at least one optical source.Type: ApplicationFiled: July 24, 2012Publication date: July 17, 2014Applicant: Diagnostic Biochips, LLCInventors: Brian Jamieson, Jennette Mateo
-
Publication number: 20140018639Abstract: Certain embodiments comprise an implantable probe for rapid measurement of multiple neurochemicals on the cellular scale in the brain. Rapid detection of multiple chemicals in vivo (animal or humans) may provide an improved understanding of acute changes in neurochemicals that occur over several seconds. The neurotransmitter chemical sensing platform may provide for continuous in vivo sensing in trials of psychoactive drugs in the laboratory animal market. The high spatial resolution of the probe may allow for chemical detection around small groups of neurons, which may help to isolate the endogenous activity of different neuron types due to disease states. Neurochemical detection may also be used to measure tissue response to exogenous stimuli, such as pharmacodynamics of drugs. The high temporal and spatial resolutions and multi-neurochemical sensing of the probe may allow for detailed studies on in vivo brain response to both endogenous and exogenous stimuli.Type: ApplicationFiled: July 15, 2013Publication date: January 16, 2014Applicant: Diagnostic Biochips LLCInventors: Brian Jamieson, Mary Emma Gorham Bigelow
-
Patent number: 8588887Abstract: Methods, systems, and apparatuses for an ingestible sensor device are described. The ingestible sensor devices may be swallowed by an animal to diagnose one or more conditions of the animal. The ingestible sensor device may include a sensor configured to receive a stimulus inside the gastrointestinal tract of an animal, wherein the sensor is configured to output a signal having a characteristic proportional to the received stimulus. The ingestible sensor device may further include a communications module that transmits a signal modulated with the sensor output signal and a housing configured to have a size that is swallowable, wherein the housing substantially encloses the sensor and communications module.Type: GrantFiled: September 6, 2007Date of Patent: November 19, 2013Assignee: Innurvation, Inc.Inventors: Michael R. Arneson, William R. Bandy, Kevin J. Powell, Brian Jamieson
-
Publication number: 20130030274Abstract: In certain embodiments, a neural probe comprises a substrate comprising elongated shanks for penetrating neural tissue, each comprising a proximal end and a distal end; at least one optical source integral to the neural probe for illuminating the neural tissue; and microelectrodes located proximate the distal end of the elongated shanks for monitoring neuronal activity. In certain embodiments, a method of monitoring neuronal activity comprises implanting the neural probe into a test subject such that the elongated shanks protrude into neural tissue of the test subject; illuminating the neural tissue with the at least one optical source; and measuring neuronal activity in response to illuminating the neural tissue. In certain embodiments, a device comprises a semiconductor chip; at least one optical source integral to the semiconductor chip; and sensor elements integral to the semiconductor chip for collecting data responsive to light emitted from the at least one optical source.Type: ApplicationFiled: July 25, 2011Publication date: January 31, 2013Applicant: DIAGNOSTIC BIOCHIPS, LLCInventors: Brian Jamieson, Jennette Mateo
-
Publication number: 20100206383Abstract: A drill cuttings transfer device that includes a pump having an inlet for receiving the drill cuttings and an outlet for discharging the drill cuttings; and a feed hopper in fluid connection to the inlet of the pump, the feed hopper comprising: at least one air nozzle configured to provide a flow of air to the drill cuttings is disclosed.Type: ApplicationFiled: July 23, 2008Publication date: August 19, 2010Applicant: M-I LLCInventors: Jonathan Getliff, Brian Jamieson
-
Publication number: 20080146871Abstract: Methods, systems, and apparatuses for an ingestible sensor device are described. The ingestible sensor devices may be swallowed by an animal to diagnose one or more conditions of the animal. The ingestible sensor device may include a sensor configured to receive a stimulus inside the gastrointestinal tract of an animal, wherein the sensor is configured to output a signal having a characteristic proportional to the received stimulus. The ingestible sensor device may further include a communications module that transmits a signal modulated with the sensor output signal and a housing configured to have a size that is swallowable, wherein the housing substantially encloses the sensor and communications module.Type: ApplicationFiled: September 6, 2007Publication date: June 19, 2008Applicant: Innurvation, Inc.Inventors: Michael R. Arneson, William R. Bandy, Kevin J. Powell, Brian Jamieson