Patents by Inventor Brian Jeffrey RUSH

Brian Jeffrey RUSH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11926850
    Abstract: The present invention relates to genetically modified yeasts that can use lactate as a carbon source to produce a fermentation product. In one aspect, the yeasts can consume glucose and lactate simultaneously to produce ethanol. In one aspect, the genetically modified yeast is transformed to include a monocarboxylic/monocarboxylate transporter. In one aspect, the yeast can include one or more heterologous genes encoding lactate dehydrogenase (cytochrome) (EC 1.1.2.3 and/or 1.1.2.4).
    Type: Grant
    Filed: March 17, 2021
    Date of Patent: March 12, 2024
    Assignee: CARGILL, INCORPORATED
    Inventors: Arlene M. Fosmer, Christopher K. Miller, Gregory Michael Poynter, Brian Jeffrey Rush, Jon Veldhouse
  • Publication number: 20230295671
    Abstract: The present disclosure provides an engineered microorganism capable of producing malonic acid, malonate, esters of malonic acid, or mixtures thereof. The engineered microorganism includes a malonate-semialdehyde dehydrogenase that is heterologous to a native form of the engineered microorganism and comprises at least 90% sequence identity to SEQ ID NO: 6, wherein the engineered microorganism is capable of producing 3 g/L to 250 g/L of malonic acid, malonate, esters of malonic acid, or mixtures thereof.
    Type: Application
    Filed: December 21, 2020
    Publication date: September 21, 2023
    Applicant: CARGILL, INCORPORATED
    Inventors: Cathy Staloch HASS, Peter Alan JAUERT, Nandita KOHLI, Panagiota KYRIAKOU, Eric Michael LENNEMAN, Hans H. LIAO, Catherine Bradshaw POOR, Brian Jeffrey RUSH, Robbyn Lynn WEAVER
  • Publication number: 20230272440
    Abstract: The present disclosure provides an engineered microorganism capable of producing malonic acid, malonate, esters of malonic acid, or mixtures thereof. The engineered microorganism includes a malonate-semialdehyde dehydrogenase that is heterologous to a native form of the engineered microorganism and comprises at least 80% sequence identity to SEQ ID NO: 6, wherein the engineered microorganism is capable of producing about 3 g/L to about 250 g/L of malonic acid, malonate, esters of malonic acid, or mixtures thereof.
    Type: Application
    Filed: December 21, 2020
    Publication date: August 31, 2023
    Applicant: CARGILL, INCORPORATED
    Inventors: Cathy Staloch HASS, Peter Alan JAUERT, Nandita KOHLI, Panagiota KYRIAKOU, Eric Michael LENNEMAN, Hans H. LIAO, Catherine Bradshaw POOR, Brian Jeffrey RUSH, Robbyn Lynn WEAVER
  • Publication number: 20230203430
    Abstract: The present disclosure provides an engineered microorganism capable of producing malonic acid, malonate, esters of malonic acid, or mixtures thereof. The engineered microorganism includes a malonate-semialdehyde dehydrogenase that is heterologous to a native form of the engineered microorganism and comprises at least 90% sequence identity to any one of SEQ ID Nos: 7, 9, 11, 13, 15, 17, 19, 21, 23, 27, 29, and 31, wherein the engineered microorganism is capable of producing about 9 g/L to about 250 g/L of malonic acid, malonate, esters of malonic acid, or mixtures thereof.
    Type: Application
    Filed: December 21, 2020
    Publication date: June 29, 2023
    Applicant: CARGILL, INCORPORATED
    Inventors: Keith Michael BRADY, Cathy Staloch HASS, Peter Alan JAUERT, Nandita KOHLI, Briana Kristen KOZLOWICZ, Hans H. LIAO, Michael Tai Man LOUIE, Michiel MATTHIJS, Naga Sirisha PARIMI, Catherine Bradshaw POOR, Brian Jeffrey RUSH, Travis Tobert WOLTER
  • Patent number: 11111482
    Abstract: The present invention relates to genetically modified yeasts that can use lactate as a carbon source to produce a fermentation product. In one aspect, the yeasts can consume gluconse and lactate simultaneously to produce ethanol. In one aspect, the genetically modified yeast is transformed to include a monocarboxylic/monocarboxylate transporter. In one aspect, the yeast can include one or more heterologous genes encoding lactate dehydrogenase (cytochrome) (EC 1.1.2.3 and/or 1.1.2.4).
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: September 7, 2021
    Assignee: CARGILL, INCORPORATED
    Inventors: Arlene M. Fosmer, Christopher K. Miller, Gregory Michael Poynter, Brian Jeffrey Rush, Jon Veldhouse
  • Publication number: 20210198637
    Abstract: The present invention relates to genetically modified yeasts that can use lactate as a carbon source to produce a fermentation product. In one aspect, the yeasts can consume glucose and lactate simultaneously to produce ethanol. In one aspect, the genetically modified yeast is transformed to include a monocarboxylic/monocarboxylate transporter. In one aspect, the yeast can include one or more heterologous genes encoding lactate dehydrogenase (cytochrome) (EC 1.1.2.3 and/or 1.1.2.4).
    Type: Application
    Filed: March 17, 2021
    Publication date: July 1, 2021
    Applicant: CARGILL, INCORPORATED
    Inventors: Arlene M. FOSMER, Christopher K. Miller, Gregory Michael Poynter, Brian Jeffrey Rush, Jon Veldhouse
  • Publication number: 20190264182
    Abstract: The present invention relates to genetically modified yeasts that can use lactate as a carbon source to produce a fermentation product. In one aspect, the yeasts can consume gluconse and lactate simultaneously to produce ethanol. In one aspect, the genetically modified yeast is transformed to include a monocarboxylic/monocarboxylate transporter. In one aspect, the yeast can include one or more heterologous genes encoding lactate dehydrogenase (cytochrome) (EC 1.1.2.3 and/or 1.1.2.4).
    Type: Application
    Filed: September 15, 2017
    Publication date: August 29, 2019
    Applicant: CARGILL, INCORPORATED
    Inventors: Arlene M. FOSMER, Christopher K. MILLER, Gregory Michael POYNTER, Brian Jeffrey RUSH, Jon VELDHOUSE