Abstract: An ingestible device (200), comprising: a housing (210, 220) comprising a stop geometry (228) at an exit hole (224); a tissue penetrating member (230) and an actuator that comprises: a pushing portion (260) configured for axial movement from a first to a second position, the pushing portion configured to move the tissue penetrating member from within the housing to a lodged position in tissue, and a holder portion (270) coupled with the pushing portion (260) for initial axial movement with the pushing portion. In the first position the holder portion releasably holds the tissue penetrating member (230) in axial retaining engagement. As the pushing portion (260) moves towards the second position, the tissue penetrating member (230) moves through the exit hole (224) until the holder portion (270) enters into engagement with the stop geometry (228). The pushing portion (260) moves further to release and advance the tissue penetrating member (230).

Abstract: An injection mold for the manufacture of an axisymmetric part of composite material comprising a mandrel supporting a fibrous preform and comprising an annular wall, and a plurality of counter-mold angular sectors assembled to the mandrel and intended to close the mold and to compact the fibrous preform wound on the mandrel. Each angular sector comprises an annular base intended to come into contact with the fibrous preform. The plurality of angular sectors includes a first series of angular sectors and a second series of angular sectors, first and second lateral edges of the first series of sectors each including a protruding lower portion, the first and the second lateral edges of the second series of sectors each including a recessed lower portion.

Abstract: A scalable flat in-plane-motion mechanical spring device. The device sincludes a frame with one or more flexures attached to the frame on a first end of the one or more flexures. The device further includes a shuttle with one or more of the one or more flexures attached to the shuttle on a second end of the one or more flexures. The frame, the shuttle, and the one or more flexures may be formed as a single piece.

Abstract: Microbially-resistant materials are disclosed and described, along with devices, surfaces, and associated methods. Such materials can be coated onto device surfaces, system surfaces, structures, and the like.

Abstract: In a general aspect, an apparatus can include a plate configured for implantation in a body of a patient. The plate can include a plurality of pores and be configured for placement between a cancellous bone of a spinal vertebra and a corresponding cartilaginous endplate as a replacement for a bony endplate of the spinal vertebra.

Abstract: A flow communication unit (240, 540, 640, 740, 840, 940, 1040, 1140, 1240) for establishing flow communication from a multi-use drug delivery device adapted for extended use, to a flow conducting device, wherein the drug delivery device comprises a reservoir comprising multiple doses of a liquid drug formulation, wherein the reservoir is adapted to pressurize the liquid drug formulation, wherein the flow conducting device (230) is adapted for conducting the drug to the subcutaneous tissue of a subject, wherein the flow communication unit is adapted for being in an unconnected and a connected configuration, whereby the flow communication unit (240, 540, 640, 740, 840, 940, 1040, 1140, 1240) is adapted to enable the extended use of the multi-use drug delivery device.

Abstract: In at least one embodiment, provided is a battery pack for a vehicle including battery pack for a vehicle, the battery pack having a firebox for enclosing batteries, an electronics compartment, thermal insulation surrounding the firebox and the electronics compartment, and heat pipes. The heat pipes may include firebox heat pipes contacting the firebox on an evaporator end and extending to an exterior surface of the battery pack on a condenser end, and electronics compartment heat pipes extending from within the electronics compartment on an evaporators end and extending through the thermal insulation to the exterior surface of the battery pack on a condenser end.

Abstract: A medical delivery device suitable for insertion into a lumen of a patient, the medical device (100, 200) comprising a capsule (110, 120, 210, 220) sized to be inserted into the lumen, the capsule comprising a base member, and an actuation mechanism comprising an actuation member (150, 250, 350) configured for movement relative to the base member along an axis, and an energy source (140, 240, 340) associated with the actuation member for powering the actuation member to move relative to the base member along the axis.

Abstract: Self-righting articles, such as self-righting capsules for administration to a subject, are generally provided. In some embodiments, the self-righting article may be configured such that the article may orient itself relative to a surface (e.g., a surface of a tissue of a subject). The self-righting articles described herein may comprise one or more tissue engaging surfaces configured to engage (e.g., interface with, inject into, anchor) with a surface (e.g., a surface of a tissue of a subject). In some embodiments, the self-righting article may have a particular shape and/or distribution of density (or mass) which, for example, enables the self-righting behavior of the article. In some embodiments, the self-righting article may comprise a tissue interfacing component and/or a pharmaceutical agent (e.g., for delivery of the active pharmaceutical agent to a location internal of the subject).

Abstract: In at least one embodiment, provided is a battery pack for a vehicle including a thin firebox for enclosing batteries and containing thermal runaway gases, thermal insulation surrounding the firebox, and a vent hole extending through the firebox and the thermal insulation to an exterior of the vehicle with vent hole plug and a pressure relief frangible vent cover at least partially covering the vent hole plug to retain it within the vent hole.

Abstract: A device for accommodating and magnetizing a tissue-penetrating medical device of various lengths, with or without a cover covering a portion or the entirety of the tissue-penetrating medical device, is disclosed including a sleeve member having an open proximal end, a distal end, an inner surface, an outer surface having a graduated injection depth gauge to indicate needle penetration depth when the cover is placed into a magnetizer, and a hollow body extending between the proximal end and the distal end to form a protective closure over a shaft of a tissue-penetrating medical device. A device having one or more magnetizing elements sectioned into a plurality of movable segments pivoting around an axis to accommodate needles with different lengths is also disclosed. Also disclosed is a device having one or more magnetizing means mounted on a movable element to magnetize needles of various lengths.

Abstract: Systems, devices, and methods for optimizing a physiological measurement are described herein. A system may include a wearable band that is wearable by a subject, a user device attached to the wearable band, and a measurement device configured to the physiological measurement. The user device may include a first communication device and a user interface. The measurement device may include a hollow housing, a processing device disposed within the housing, an elastic coupling member disposed within the housing, a physiological sensor coupled to the housing by the elastic coupling member, and a second communication device. The physiological sensor may take the physiological measurement and communicate the physiological measurement to the user device. The user interface may display the physiological measurement to the subject. The physiological measurement device and the user device may be attached to the same wearable band that is worn by the subject.

Abstract: Systems, devices, and methods are described herein for maintaining a physiological sensor at constant pressure against a subject. A system may include a wearable band that is wearable by a subject, a physiological sensor coupled to the wearable band, a pressure sensor coupled to the wearable band, a processor and a user interface. The physiological sensor may be positioned along an inside surface of the wearable band, embedded in the wearable band, or otherwise positioned in the band to be adjacent to the subject as the subject wears the wearable band. The pressure sensor may directly or indirectly measure a pressure of the physiological sensor against the subject. The processor may generate an alert when a pressure measurement for the physiological sensor against the subject is outside a specified range. The user interface may present the alert to the subject.

Abstract: Systems, devices, and methods are described herein for ensuring constant contact of a physiological sensor with a subject. A device may include a wearable band wearable by the subject, an elastic coupling member, a sensor module coupled by the elastic coupling member to the wearable band, a housing attached to the wearable band, a processor, and a user interface. The wearable band may include a recess extending into the wearable band. The elastic coupling member and/or the sensor module may be disposed within the recess. As the subject wears the wearable band, the elastic coupling member may press the sensor module against the subject and may cause constant contact between the sensor module and the subject. Electrical tracing embedded in the wearable band and extending from the sensor module to the housing may couple the sensor module to the processor or the user interface.

Abstract: Systems and methods are provided for generating a virtual reality (VR) simulation of a retail store, which simulation is configured and displayed on an immersive VR display device that enables a user to experience the simulated retail store as if it were a physical retail store. The systems enable the user to arrange display cases and other interior store components, and to populate shelves, racks, and the like, with products to be sold in the retail store. A VR platform enables multiple users to synchronously view the VR simulation and make coordinated changes to develop an optimized configuration of the retail store. Marketing, sales, merchant, and other data may be collected, aggregated, and analyzed to identify purchase trends of certain products; the analyzed data may identify user shopping preferences, and the VR platform may generate a customized retail store including only products relevant to a user.

Abstract: Self-righting articles, such as self-righting capsules for administration to a subject, are generally provided. In some embodiments, the self-righting article may be configured such that the article may orient itself relative to a surface (e.g., a surface of a tissue of a subject). The self-righting articles described herein may comprise one or more tissue engaging surfaces configured to engage (e.g., interface with, inject into, anchor) with a surface (e.g., a surface of a tissue of a subject). In some embodiments, the self-righting article may have a particular shape and/or distribution of density (or mass) which, for example, enables the self-righting behavior of the article. In some embodiments, the self-righting article may comprise a tissue interfacing component and/or a pharmaceutical agent (e.g., for delivery of the active pharmaceutical agent to a location internal of the subject) such as a liquid pharmaceutical agent.

Abstract: Systems and methods of managing videoconferencing endpoint capacity based on safety concerns (e.g., COVID-19), comprising: capturing a video feed corresponding to a geographic location; detecting a presence of one or more persons corresponding to the geographic location, based on data of the video feed; determining a quantity of persons corresponding to the geographic location, based the data of the video feed; determining that the quantity of persons corresponding to the geographic location exceeds a first predetermined threshold; and—in response to the determination that the quantity of persons corresponding to the geographic location exceeds the first predetermined threshold—issuing one or more alert messages and/or taking other appropriate action(s).

Abstract: Capsule devices, such as devices suitable for swallowing into a lumen of a body lumen, are generally provided. In some embodiments, the capsule device (100) comprises a tissue interfacing component (130) disposed relative to a capsule housing (110,120). The capsule device (100) may comprise a plurality of elongated spike members (182, 130) advanceable relative to the capsule housing (110,120) from a non-advanced first state to an advanced second state, wherein free ends of the elongated spike members (182, 130) engages tissue of a lumen wall of the body lumen. In some embodiments, the capsule device (100) comprises an actuator (155) coupled to the plurality of elongate spike members (182) and an energy source (140) coupled to the actuator (155) for moving the plurality of elongated spike members (182, 130) to the advanced second state.

Abstract: Self-righting articles, such as self-righting capsules for administration to a subject, are generally provided. In some embodiments, the self-righting article may be configured such that the article may orient itself relative to a surface. The self-righting articles described herein may comprise one or more tissue engaging surfaces configured to engage with a surface. In some embodiments, the self-righting article may have a particular shape and/or distribution of density (or mass) which, for example, enables the self-righting behavior of the article. In some embodiments, the self-righting article may comprise a tissue interfacing component and/or a pharmaceutical agent (e.g., for delivery of the active pharmaceutical agent to a location internal of the subject). In some cases, upon contact of the tissue with the tissue engaging surface of the article, the self-righting article may be configured to release one or more tissue interfacing components.

Abstract: An adjustable measurement device is described that may include a housing, a power supply, a processor, a communication device, an elastic coupling member, a physiological sensor, and/or a clamp. The housing may be configured to attach to a wearable band that is wearable by a subject. The housing may include a chamber within the housing. The power supply, the processor, the communication device, the elastic coupling member, and or the physiological sensor may be disposed within the chamber. The elastic coupling member may couple the physiological sensor to the housing. A force exerted by the elastic coupling member on the physiological sensor may be in a direction through an opening towards a body part of a subject. As the subject wears the wearable band and the housing is coupled to the wearable band, the physiological sensor may be adjacent to or contact the subject.