Patents by Inventor Brian John CAMERON

Brian John CAMERON has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for predicting the off-target binding of a peptide which binds to a target peptide presented by a major histocompatibility complex
    Patent number: 11929151
    Abstract: The invention provides a method for predicting whether a binding peptide, which binds to a target peptide presented by a Major Histocompatibility Complex (MHC) and is for administration to a subject, has the potential to cross react with another peptide in the subject in vivo. The method comprises the steps of identifying at least one binding motif in the target peptide to which the binding peptide binds; and searching for peptides that are present in the subject that comprise the at least one binding motif and that are not the target peptide. The presence of one or more such peptides indicates that the binding peptide has the potential to cross react in vivo.
    Type: Grant
    Filed: January 26, 2021
    Date of Patent: March 12, 2024
    Assignees: Immunocore Limited, Adaptimmune Limited
    Inventors: Brian John Cameron, Annelise Brigitte Vuidepot, Bent Karsten Jakobsen
  • METHOD FOR PREDICTING THE OFF-TARGET BIDING OF A PEPTIDE WHICH BINDS TO A TARGET PEPTIDE PRESENTED BY A MAJOR HISTOCOMPATIBILITY COMPLEX
    Publication number: 20210241854
    Abstract: The invention provides a method for predicting whether a binding peptide, which binds to a target peptide presented by a Major Histocompatibility Complex (MHC) and is for administration to a subject, has the potential to cross react with another peptide in the subject in vivo. The method comprises the steps of identifying at least one binding motif in the target peptide to which the binding peptide binds; and searching for peptides that are present in the subject that comprise the at least one binding motif and that are not the target peptide. The presence of one or more such peptides indicates that the binding peptide has the potential to cross react in vivo.
    Type: Application
    Filed: January 26, 2021
    Publication date: August 5, 2021
    Inventors: Brian John CAMERON, Annelise Brigitte VUIDEPOT, Bent Karsten JAKOBSEN
  • Method for predicting the off-target biding of a peptide which binds to a target peptide presented by a major histocompatibility complex
    Patent number: 11017882
    Abstract: The invention provides a method for predicting whether a binding peptide, which binds to a target peptide presented by a Major Histocompatibility Complex (MHC) and is for administration to a subject, has the potential to cross react with another peptide in the subject in vivo. The method comprises the steps of identifying at least one binding motif in the target peptide to which the binding peptide binds; and searching for peptides that are present in the subject that comprise the at least one binding motif and that are not the target peptide. The presence of one or more such peptides indicates that the binding peptide has the potential to cross react in vivo.
    Type: Grant
    Filed: June 17, 2015
    Date of Patent: May 25, 2021
    Assignees: Immunocore Limited, Adaptimmune Limited
    Inventors: Brian John Cameron, Annelise Brigitte Vuidepot, Bent Karsten Jakobsen
  • Method for predicting the off-target biding of a peptide which binds to a target peptide presented by a major histocompatibility complex
    Patent number: 10937524
    Abstract: The invention provides a method for predicting whether a binding peptide, which binds to a target peptide presented by a Major Histocompatibility Complex (MHC) and is for administration to a subject, has the potential to cross react with another peptide in the subject in vivo. The method comprises the steps of identifying at least one binding motif in the target peptide to which the binding peptide binds; and searching for peptides that are present in the subject that comprise the at least one binding motif and that are not the target peptide. The presence of one or more such peptides indicates that the binding peptide has the potential to cross react in vivo.
    Type: Grant
    Filed: June 17, 2015
    Date of Patent: March 2, 2021
    Assignees: Immunocore Limited, Adaptimmune Limited
    Inventors: Brian John Cameron, Annelise Brigitte Vuidepot, Bent Karsten Jakobsen
  • METHOD FOR PREDICTING THE OFF-TARGET BIDING OF A PEPTIDE WHICH BINDS TO A TARGET PEPTIDE PRESENTED BY A MAJOR HISTOCOMPATIBILITY COMPLEX
    Publication number: 20150284877
    Abstract: The invention provides a method for predicting whether a binding peptide, which binds to a target peptide presented by a Major Histocompatibility Complex (MHC) and is for administration to a subject, has the potential to cross react with another peptide in the subject in vivo. The method comprises the steps of identifying at least one binding motif in the target peptide to which the binding peptide binds; and searching for peptides that are present in the subject that comprise the at least one binding motif and that are not the target peptide. The presence of one or more such peptides indicates that the binding peptide has the potential to cross react in vivo.
    Type: Application
    Filed: June 17, 2015
    Publication date: October 8, 2015
    Inventors: Brian John CAMERON, Annelise Brigitte VUIDEPOT, Bent Karsten JAKOBSEN