Patents by Inventor Brian Kenneth Raymer

Brian Kenneth Raymer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted Fused Bicyclic Compounds and Related Methods of Treatment
    Publication number: 20250230141
    Abstract: The present invention provides compounds useful for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.
    Type: Application
    Filed: December 17, 2024
    Publication date: July 17, 2025
    Inventors: Sudhir Mahadeo HANDE, Yuan HU, Younggi CHOI, Hoan HUYNH, Brian M. AQUILA, Ingo Andreas MUGGE, Brian Kenneth RAYMER, Christopher A. WILHELMSEN, Lewis D. PENNINGTON, Jonathan Ward LEHMANN
  • Substituted Fused Bicyclic Compounds and Related Methods of Treatment
    Publication number: 20250230142
    Abstract: The present invention provides compounds useful for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.
    Type: Application
    Filed: December 17, 2024
    Publication date: July 17, 2025
    Inventors: Sudhir Mahadeo HANDE, Yuan HU, Younggi CHOI, Hoan HUYNH, Brian M. AQUILA, Ingo Andreas MUGGE, Brian Kenneth RAYMER, Christopher A. WILHELMSEN, Lewis D. PENNINGTON, Jonathan Ward LEHMANN
  • Substituted Pyrrolidinyl And Piperidinyl Compounds And Related Methods Of Treatment
    Publication number: 20250223276
    Abstract: The present invention provides compounds useful for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.
    Type: Application
    Filed: December 17, 2024
    Publication date: July 10, 2025
    Inventors: Sudhir Mahadeo HANDE, Yuan HU, Younggi CHOI, Hoan HUYNH, Brian M. AQUILA, Ingo Andreas MUGGE, Brian Kenneth RAYMER, Byung-Chul SUH, Lewis D. PENNINGTON, Jonathan Ward LEHMANN
  • Substituted Pyrrolidinyl And Piperidinyl Compounds And Related Methods Of Treatment
    Publication number: 20250223260
    Abstract: The present invention provides compounds useful for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.
    Type: Application
    Filed: December 17, 2024
    Publication date: July 10, 2025
    Inventors: Sudhir Mahadeo HANDE, Yuan HU, Younggi CHOI, Hoan HUYNH, Brian M. AQUILA, Ingo Andreas MUGGE, Brian Kenneth RAYMER, Byung-Chul SUH, Lewis D. PENNINGTON, Jonathan Ward LEHMANN
  • Substituted Macrocyclic Compounds and Related Methods of Treatment
    Publication number: 20250092063
    Abstract: The present invention provides compounds useful for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.
    Type: Application
    Filed: June 17, 2024
    Publication date: March 20, 2025
    Inventors: Lewis D. PENNINGTON, Younggi CHOI, Hoan HUYNH, Brian M. AQUILA, Ingo Andreas MUGGE, Yuan HU, James R. WOODS, Roman A. VALIULIN, Brian Kenneth RAYMER, Jörg Martin BENTZIEN, Michael R. HALE, Jonathan Ward LEHMANN, Daljit MATHARU, Srinivasa KARRA
  • Substituted Macrocyclic Compounds and Related Methods of Treatment
    Publication number: 20240368182
    Abstract: The present invention provides compounds useful for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.
    Type: Application
    Filed: April 5, 2024
    Publication date: November 7, 2024
    Inventors: Lewis D. PENNINGTON, Younggi CHOI, Hoan HUYNH, Brian M. AQUILA, Ingo Andreas MUGGE, Yuan HU, James R. WOODS, Brian Kenneth RAYMER, Jörg Martin BENTZIEN, Jonathan Ward LEHMANN, Michael R. HALE, Srinivasa KARRA, Roman A. VALIULIN, Daljit MATHARU
  • Substituted macrocyclic compounds and related methods of treatment
    Patent number: 12054495
    Abstract: The present invention provides compounds useful for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.
    Type: Grant
    Filed: November 22, 2022
    Date of Patent: August 6, 2024
    Assignee: Alkermes, Inc.
    Inventors: Lewis D. Pennington, Younggi Choi, Hoan Huynh, Brian M. Aquila, Ingo Andreas Mugge, Yuan Hu, James R. Woods, Roman A. Valiulin, Brian Kenneth Raymer, Jörg Martin Bentzien, Michael R. Hale, Jonathan Ward Lehmann, Daljit Matharu, Srinivasa Karra
  • Substituted macrocyclic compounds and related methods of treatment
    Patent number: 12006330
    Abstract: The present invention provides compounds useful for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.
    Type: Grant
    Filed: December 20, 2021
    Date of Patent: June 11, 2024
    Assignee: Alkermes, Inc.
    Inventors: Lewis D. Pennington, Younggi Choi, Hoan Huynh, Brian M. Aquila, Ingo Andreas Mugge, Yuan Hu, James R. Woods, Brian Kenneth Raymer, Jörg Martin Bentzien, Jonathan Ward Lehmann, Michael R. Hale, Srinivasa Karra, Roman A. Valiulin, Daljit Matharu
  • SUBSTITUTED FUSED BICYCLIC MACROCYCLIC COMPOUNDS AND RELATED METHODS OF TREATMENT
    Publication number: 20240182491
    Abstract: The present invention provides compounds useful for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.
    Type: Application
    Filed: November 14, 2023
    Publication date: June 6, 2024
    Inventors: Hoan Huynh, Lewis D. Pennington, Younggi Choi, Brian M. Aquila, Ingo Andreas Mugge, Yuan Hu, James R. Woods, Brian Kenneth Raymer, Jörg Martin Bentzien, Jonathan Ward Lehmann, Michael R. Hale
  • SUBSTITUTED CARBAMATE MACROCYCLIC COMPOUNDS AND RELATED METHODS OF TREATMENT
    Publication number: 20240174689
    Abstract: The present invention provides compounds useful for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.
    Type: Application
    Filed: November 14, 2023
    Publication date: May 30, 2024
    Inventors: Lewis D. Pennington, Younggi Choi, Hoan Huynh, Brian M. Aquila, Ingo Andreas Mugge, Yuan Hu, James R. Woods, Brian Kenneth Raymer, Jörg Martin Bentzien, Jonathan Ward Lehmann, Michael R. Hale
  • SUBSTITUTED AMIDE MACROCYCLIC COMPOUNDS WITH OREXIN-2 RECEPTOR AGONIST ACTIVITY
    Publication number: 20240124485
    Abstract: The present invention provides compounds useful for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.
    Type: Application
    Filed: October 3, 2023
    Publication date: April 18, 2024
    Inventors: Younggi Choi, Yuan Hu, Hoan Huynh, Brian M. Aquila, Brian Kenneth Raymer, Ingo Andreas Mugge, James R. Woods, Lewis D. Pennington, Jörg Martin Bentzien, Jonathan Ward Lehmann, Michael R. Hale, Roman A. Valiulin
  • Substituted Piperidino Compounds and Related Methods of Treatment
    Publication number: 20240076283
    Abstract: The present invention provides compounds useful for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.
    Type: Application
    Filed: August 4, 2023
    Publication date: March 7, 2024
    Inventors: Lewis D. Pennington, Younggi Choi, Hoan Huynh, Brian M. Aquila, Ingo Andreas Mugge, Yuan Hu, James R. Woods, Brian Kenneth Raymer, Jörg Martin Bentzien, Jonathan Ward Lehmann, Srinivasa Karra, Roman A. Valiulin, Daljit Matharu
  • SUBSTITUTED MACROCYCLIC COMPOUNDS AND RELATED METHODS OF TREATMENT
    Publication number: 20230339969
    Abstract: The present invention provides compounds useful for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.
    Type: Application
    Filed: November 22, 2022
    Publication date: October 26, 2023
    Inventors: Lewis D. Pennington, Younggi Choi, Hoan Huynh, Brian M. Aquila, Ingo Andreas Mugge, Yuan Hu, James R. Woods, Roman A. Valiulin, Brian Kenneth Raymer, Jörg Martin Bentzien, Michael R. Hale, Jonathan Ward Lehmann, Daljit Matharu, Srinivasa Karra
  • Substituted piperidino compounds and related methods of treatment
    Patent number: 11760747
    Abstract: The present invention provides compounds useful for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.
    Type: Grant
    Filed: December 20, 2021
    Date of Patent: September 19, 2023
    Assignee: Alkermes, Inc.
    Inventors: Lewis D. Pennington, Younggi Choi, Hoan Huynh, Brian M. Aquila, Ingo Andreas Mugge, Yuan Hu, James R. Woods, Brian Kenneth Raymer, Jörg Martin Bentzien, Jonathan Ward Lehmann, Srinivasa Karra, Roman A. Valiulin, Daljit Matharu
  • Substituted macrocyclic compounds and related methods of treatment
    Patent number: 11542276
    Abstract: The present invention provides compounds useful for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.
    Type: Grant
    Filed: November 25, 2020
    Date of Patent: January 3, 2023
    Assignee: Alkermes, Inc.
    Inventors: Lewis D. Pennington, Younggi Choi, Hoan Huynh, Brian M. Aquila, Ingo Andreas Mugge, Yuan Hu, James R. Woods, Roman A. Valiulin, Brian Kenneth Raymer, Jörg Martin Bentzien, Michael R. Hale, Jonathan Ward Lehmann, Daljit Matharu, Srinivasa Karra
  • Substituted Macrocyclic Compounds and Related Methods of Treatment
    Publication number: 20220194958
    Abstract: The present invention provides compounds useful for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.
    Type: Application
    Filed: December 20, 2021
    Publication date: June 23, 2022
    Inventors: Lewis D. Pennington, Younggi Choi, Hoan Huynh, Brian M. Aquila, Ingo Andreas Mugge, Yuan Hu, James R. Woods, Brian Kenneth Raymer, Jörg Martin Bentzien, Jonathan Ward Lehmann, Michael R. Hale, Srinivasa Karra, Roman A. Valiulin, Daljit Matharu
  • SUBSTITUTED PIPERIDINO COMPOUNDS AND RELATED METHODS OF TREATMENT
    Publication number: 20220194926
    Abstract: The present invention provides compounds useful for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.
    Type: Application
    Filed: December 20, 2021
    Publication date: June 23, 2022
    Inventors: Lewis D. Pennington, Younggi Choi, Hoan Huynh, Brian M. Aquila, Ingo Andreas Mugge, Yuan HU, James R. Woods, Brian Kenneth Raymer, Jörg Martin Bentzien, Jonathan Ward Lehmann, Srinivasa Karra, Roman A. Valiulin, Daljit Matharu
  • Substituted Macrocyclic Compounds and Related Methods of Treatment
    Publication number: 20210155636
    Abstract: The present invention provides compounds useful for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.
    Type: Application
    Filed: November 25, 2020
    Publication date: May 27, 2021
    Inventors: Lewis D. Pennington, Younggi Choi, Hoan Huynh, Brian M. Aquila, Ingo Mugge, Yuan HU, James R. Woods, Roman A. Valiulin, Brian Kenneth Raymer, Jorg Martin Bentzien, Michael R. Hale, Jonathan Ward Lehmann, Daljit Matharu, Srinivasa Karra
  • Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof
    Patent number: 9789118
    Abstract: The present invention provides compounds of formula (IV); or pharmaceutically acceptable salts thereof, wherein the variables are defined as herein. The present invention provides a method for manufacturing the compounds of formula (IV), their therapeutic uses, combinations with other of pharmacologically active agents, and a pharmaceutical compositions.
    Type: Grant
    Filed: February 24, 2014
    Date of Patent: October 17, 2017
    Assignee: NOVARTIS AG
    Inventors: David Weninger Barnes, Gregory Raymond Bebernitz, Kevin Clairmont, Scott Louis Cohen, Robert Edson Damon, II, Robert Francis Day, Stephanie Kay Dodd, Christoph Gaul, Hatice Belgin Gulgeze Efthymiou, Monish Jain, Rajeshri Ganesh Karki, Louise Clare Kirman, Kai Lin, Justin Yik Ching Mao, Tajesh Jayprakash Patel, Brian Kenneth Raymer, Su Liansheng
  • BICYCLIC ACETYL-COA CARBOXYLASE INHIBITORS AND USES THEREOF
    Publication number: 20140171363
    Abstract: The present invention provides compounds of formula (I); or pharmaceutically acceptable salts thereof, wherein the variables are defined as herein. The present invention provides a method for manufacturing the compounds of formula (I), their therapeutic uses, combinations with other of pharmacologically active agents, and a pharmaceutical compositions.
    Type: Application
    Filed: February 24, 2014
    Publication date: June 19, 2014
    Applicant: NOVARTIS AG
    Inventors: David Weninger BARNES, Gregory Raymond BEBERNITZ, Kevin CLAIRMONT, Scott Louis COHEN, Robert Edson DAMON, II, Robert Francis DAY, Stephanie Kay DODD, Christoph GAUL, Hatice Belgin GULGEZE EFTHYMIOU, Monish JAIN, Rajeshri Ganesh KARKI, Louise Clare KIRMAN, Kai LIN, Justin Yik Ching MAO, Tajesh Jayprakash PATEL, Brian Kenneth RAYMER, SU Liansheng