Abstract: The present disclosure relates to formulations, such as tablets, of FXR agonists and therapeutic uses thereof. The disclosure also relates to methods for obtaining such formulations.

Abstract: A trip apparatus for a circuit interruption device that comprises a coil operatively connectable to a circuit interruption device. The coil is configured to selectively operate the circuit interruption device to interrupt when a current flowing through the circuit interruption device exceeds a threshold. The trip apparatus also includes a current measuring device configured to selectively measure a coil current flowing through the coil to determine a measured coil current signal. In addition, the trip apparatus includes a monitoring device configured to determine the derivative of the measured coil current signal and to perform a correlation of the derivative of the measured coil current signal and a reference derivative of a reference coil current signal to determine a correlation output. The monitoring device is further configured to compare the correlation output with a reference correlation threshold to determine whether an operating condition of the coil is normal or abnormal.

Abstract: The present disclosure relates to formulations, such as tablets, of FXR agonists and therapeutic uses thereof. The disclosure also relates to methods for obtaining such formulations.

Abstract: A system and method is disclosed which monitors factors in order to prevent impending component failure within a mechanical system, such as an aircraft. The monitoring system monitors the health and condition of system components, and utilizes proprietary algorithms to predict impending failures in monitored components before failure occurs. The system can shut down a component, send an alert, or adjust component thresholds as required.

Abstract: A system and method is disclosed which monitors factors in order to prevent impending component failure within a mechanical system, such as an aircraft. The monitoring system monitors the health and condition of system components, and utilizes proprietary algorithms to predict impending failures in monitored components before failure occurs. The system can shut down a component, send an alert, or adjust component thresholds as required.

Abstract: A trip apparatus for a circuit interruption device that comprises a coil operatively connectable to a circuit interruption device. The coil is configured to selectively operate the circuit interruption device to interrupt when a current flowing through the circuit interruption device exceeds a threshold. The trip apparatus also includes a current measuring device configured to selectively measure a coil current flowing through the coil to determine a measured coil current signal. In addition, the trip apparatus includes a monitoring device configured to determine the derivative of the measured coil current signal and to perform a correlation of the derivative of the measured coil current signal and a reference derivative of a reference coil current signal to determine a correlation output. The monitoring device is further configured to compare the correlation output with a reference correlation threshold to determine whether an operating condition of the coil is normal or abnormal.

Abstract: A system and method is disclosed which monitors factors in order to prevent impending component failure within a mechanical system, such as an aircraft. The monitoring system monitors the health and condition of system components, and utilizes proprietary algorithms to predict impending failures in monitored components before failure occurs. The system can shut down a component, send an alert, or adjust component thresholds as required.

Abstract: A bio-information monitoring system passively monitors a patient with a remote portable bio-information unit that takes various bio-information measurements at selected time intervals as well as at random times without patient intervention. The measurements are converted to digital signals which are transmitted from the bio-information unit to a modem when the bio-information unit is in proximity to the modem. The signals are stored in the modem and uploaded to a central monitoring network. Automatic alerts may be sent from the central monitoring network to a treatment provider. The treatment provider may also access the information through secured dedicated websites via the Internet.

Abstract: A communication connector system for connecting with a peripheral communication connector having a peripheral housing with at least one of a peripheral contact, a peripheral magnet and a peripheral detent and methods for manufacturing and using same. The communication connector system includes a housing assembly with a mating surface. A system contact is disposed on the mating surface and can cooperate with the peripheral contact; whereas, a system magnet is provided in the housing assembly and can cooperate with the peripheral magnet. A magnetically coupling between the system magnet and the peripheral magnet can retain the housing assembly in connection with the peripheral housing during use. The housing assembly likewise can include a housing assembly detent for cooperating with the peripheral detent. An electrical connection between the communication connector and the peripheral communication connector thereby can advantageously be formed via the system contact or the housing assembly detent.

Abstract: A portable testing unit for biometric identity confirmation includes a housing with an orifice to receive a breath sample from the test subject, a spirometric sensor, and a pulse sensor adjacent to the orifice. A processor analyzes spirometric data from the spirometric sensor and simultaneous pulse wave data from the pulse sensor during the breath sample, together with stored subject characterization data for a known subject to confirm whether the identity of the test subject matches the known subject. A communications link enables the processor to communicate to the external station whether the identity of the test subject matches the known subject. For example, this portable testing unit can be used to control access to a secure facility or computer, authenticate the identity of a party in a financial transaction, or confirm the identity of the subject of an alcohol monitoring test.

Abstract: Quantum key distribution QKD systems and methods are provided that allow for QKD over distances not previously achievable. In one embodiment, the QKD system and method utilizes state discrimination techniques. In another embodiment, the QKD system and method utilizes amplifiers and unitary transformations to extend the range over which QKD can be achieved. The QKD systems and methods of the present invention can be used to implement secure quantum communications systems.

Abstract: A communication connector system for connecting with a peripheral communication connector having a peripheral housing with at least one of a peripheral contact, a peripheral magnet and a peripheral detent and methods for manufacturing and using same. The communication connector system includes a housing assembly with a mating surface. A system contact is disposed on the mating surface and can cooperate with the peripheral contact; whereas, a system magnet is provided in the housing assembly and can cooperate with the peripheral magnet. A magnetically coupling between the system magnet and the peripheral magnet can retain the housing assembly in connection with the peripheral housing during use. The housing assembly likewise can include a housing assembly detent for cooperating with the peripheral detent. An electrical connection between the communication connector and the peripheral communication connector thereby can advantageously be formed via the system contact or the housing assembly detent.

Abstract: An information system suitable for use in cooperation with portable media devices, such as an Apple iPod® digital electronic media device, and methods for manufacturing and using same. The information system supports a simple manner for seamlessly integrating the personal media device with the information system, immersing a user in a rich and intuitive media environment. When the personal media device and the information system are coupled, viewing content from the personal media device can be integrated “on the fly” into the information system via an interactive user interface system. The personal media device likewise can receive control commands and/or operating power from the information system. Thereby, the user can advantageously enjoy his own personal viewing content from the personal media device via the larger video presentation system and/or the enhanced audio presentation system of the information system, while recharging an internal battery system of the personal media device.

Abstract: A personal user control device suitable for use in cooperation with information systems, such as vehicle information systems, and methods for manufacturing and using same. The personal user control device provides a user-friendly interface system for interacting with the information system. Unlike conventional control devices, the user interface system includes no dedicated buttons and provides a customizable environment for interacting with the information system. When in communication with the information system, the personal user control device can automatically detect system status information, such as available system functionality, available viewing content, and/or a current system operation mode, of the information system and provides a user interface system that instinctively adapts for use with the information system in light of the detected system status information. The personal user control device thereby provides a versatile and intuitive manner for interacting with the information system.

Abstract: A tamper proof transdermal alcohol content monitoring device is made up of analog and digital sides which are securely attached to the human subject to be monitored. The analog side has a sampling circuit which draws a measured insensible skin perspiration sample from the skin of the subject and measured with an electrochemical fuel cell. A distance measurement of the device from the skin of the subject and temperature of the sample are monitored along with the transdermal alcohol content, and converted to digital signals which are transmitted to a modem when the monitor is in proximity to the modem. The signals are stored in the modem and uploaded to a central monitoring station. Automatic alerts may be sent from the central monitoring station to a supervising agency. The supervising agency may also access the information through secured dedicated websites via the Internet.

Abstract: A tamper proof transdermal alcohol content monitoring device is made up of analog and digital sides which are securely attached to the human subject to be monitored. The analog side has a sampling circuit which draws a measured insensible skin perspiration sample from the skin of the subject and measured with an electrochemical fuel cell. A distance measurement of the device from the skin of the subject and temperature of the sample are monitored along with the transdermal alcohol content, and converted to digital signals which are transmitted to a modem when the monitor is in proximity to the modem. The signals are stored in the modem and uploaded to a central monitoring station. Automatic alerts may be sent from the central monitoring station to a supervising agency. The supervising agency may also access the information through secured dedicated websites via the Internet.

Abstract: A tamper proof transdermal alcohol content monitoring device is made up of analog and digital sides which are securely attached to the human subject to be monitored. The analog side has a sampling circuit which draws a measured insensible skin perspiration sample from the skin of the subject and measured with an electrochemical fuel cell. A distance measurement of the device from the skin of the subject and temperature of the sample are monitored along with the transdermal alcohol content, and converted to digital signals which are transmitted to a modem when the monitor is in proximity to the modem. The signals are stored in the modem and uploaded to a central monitoring station. Automatic alerts may be sent from the central monitoring station to a supervising agency. The supervising agency may also access the information through secured dedicated websites via the Internet.

Abstract: An information system suitable for use in cooperation with portable media devices, such as an Apple iPhone® digital electronic media device, and methods for manufacturing and using same. The information system includes a wireless access point and supports a simple manner for seamlessly integrating the personal media device with the information system, immersing a user in a rich and intuitive media environment. When disposed within a predetermined range of the wireless access point, the portable media device and the vehicle information system can initiate, and maintain, communications, preferably without requiring authentication of the portable media device. The personal media device thereby can exchange control commands and viewing content with the information system. Thereby, a user can advantageously enjoy selected viewing content provided by the information system via the personal media device.

Abstract: A personal user control device suitable for use in cooperation with information systems, such as vehicle information systems, and methods for manufacturing and using same. The personal user control device provides a user-friendly interface system for interacting with the information system. Unlike conventional control devices, the user interface system includes no dedicated buttons and provides a customizable environment for interacting with the information system. When in communication with the information system, the personal user control device can automatically detect system status information, such as available system functionality, available viewing content, and/or a current system operation mode, of the information system and provides a user interface system that instinctively adapts for use with the information system in light of the detected system status information. The personal user control device thereby provides a versatile and intuitive manner for interacting with the information system.

Abstract: An information system suitable for use in cooperation with portable media devices, such as an Apple iPod® digital electronic media device, and methods for manufacturing and using same. The information system supports a simple manner for seamlessly integrating the personal media device with the information system, immersing a user in a rich and intuitive media environment. When the personal media device and the information system are coupled, viewing content from the personal media device can be integrated “on the fly” into the information system via an interactive user interface system. The personal media device likewise can receive control commands and/or operating power from the information system. Thereby, the user can advantageously enjoy his own personal viewing content from the personal media device via the larger video presentation system and/or the enhanced audio presentation system of the information system, while recharging an internal battery system of the personal media device.