Patents by Inventor Brian L. Bates
Brian L. Bates has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7731685Abstract: A coated medical device adapted for introduction into a passage or vessel of a patient is provided. The medical device is preferably an implantable balloon with a bioactive deposited or within the balloon. The balloon can further include a hydrophilic material positioned between the balloon and a bioactive material posited on the balloon.Type: GrantFiled: September 23, 2005Date of Patent: June 8, 2010Assignees: Cook Incorporated, MED Institute, Inc.Inventors: Anthony O. Ragheb, Brian L. Bates, Scott E. Boatman, David G. Burton, Michael C. Hoffa, Darin G. Schaeffer, Jason S. Sturgeon
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Patent number: 7691140Abstract: An anastomosis device (12) for advantageously bridging an artery and a vein. The anastomosis device includes a tubular graft (15) with first and second ends (47 and 48) and a longitudinal passageway extending longitudinally through the graft. The device further includes a first stent (10) disposed about the first end of the tubular graft and a second stent (10) disposed about the second end of the tubular graft. Each of the first and second stents has a plurality of hooks or barbs (11) pointed or releasable to the point toward the other end of the graft.Type: GrantFiled: May 12, 2004Date of Patent: April 6, 2010Assignees: Cook Incorporated, Cook Biotech IncorporatedInventors: Brian L. Bates, Clay D. Fette, Ram H. Paul, Jr., Paul D. Amarant
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Publication number: 20100049309Abstract: A coated medical device (10) including a structure (12) adapted for introduction into a passage or vessel of a patient. The structure is formed of preferably a non-porous base material (14) having a bioactive material layer (18) disposed thereon. The medical device is preferably an implantable stent or balloon (26) of which the bioactive material layer is deposited thereon. The stent can be positioned around the balloon and another layer of the bioactive material posited over the entire structure and extending beyond the ends of the positioned stent. The ends of the balloon extend beyond the ends of the stent and include the bioactive material thereon for delivering the bioactive material to the cells of a vessel wall coming in contact therewith. The balloon further includes a layer of hydrophilic material (58) positioned between the base and bioactive material layers of the balloon.Type: ApplicationFiled: October 30, 2009Publication date: February 25, 2010Inventors: Brian L. Bates, Anthony O. Ragheb, Joseph M. Stewart, IV, William J. Bourdeau, Brian D. Choules, James D. Purdy, Neal E. Fearnot
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Publication number: 20090285975Abstract: A coated implantable medical device 10 includes a structure 12 adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract; at least one coating layer 16 posited on one surface of the structure; and at least one layer 18 of a bioactive material posited on at least a portion of the coating layer 16, wherein the coating layer 16 provides for the controlled release of the bioactive material from the coating layer. In addition, at least one porous layer 20 can be posited over the bioactive material layer 18, wherein the porous layer includes a polymer and provides for the controlled release of the bioactive material therethrough. Preferably, the structure 12 is a coronary stent. The porous layer 20 includes a polymer applied preferably by vapor or plasma deposition and provides for a controlled release of the bioactive material.Type: ApplicationFiled: June 23, 2009Publication date: November 19, 2009Inventors: Brian L. Bates, Anthony O. Ragheb, Neal E. Fearnot, Thomas G. Kozma, William D. Voorhees, III
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Patent number: 7611533Abstract: A coated implantable medical device 10 includes a structure 12 adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract, and at least one layer 18 of an immunosuppressive agent posited over at least one surface of the structure 12. Optionally, the device 10 can include at least one porous, preferably polymeric layer 20 posited over the layer 18 of immunosuppressive agent, and can alternatively or additionally include at least one coating layer 16 posited on one surface of the structure 12, the at least one layer 18 of immunosuppessive agent being posited in turn on at least a portion of the coating layer 16. The porous layer 20 and the coating layer 16 each provide for the controlled release of the bioactive material from the device 10. The structure 12 is preferably configured as a coronary stent. The polymer of the porous layer 20 is preferably applied by vapor or plasma deposition.Type: GrantFiled: August 19, 2002Date of Patent: November 3, 2009Assignee: Cook IncorporatedInventors: Brian L. Bates, Anthony O. Ragheb, Neal E. Fearnot, Thomas G. Kozma, William D. Voorhees, III, Thomas A. Osborne
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Patent number: 7611532Abstract: Disclosed in one embodiment is a medical device including an expandable metal vascular stent including at least one surface. A coating layer including parylene or a parylene derivative is positioned on the at least one surface. At least one layer comprising a bioactive agent is positioned on the coating layer, wherein the bioactive agent is selected from the group consisting of an immunosuppressive agent, anti-inflammatory agent and an anti-proliferative agent. A porous layer is positioned on the at least one layer including a bioactive agent, wherein upon implantation into a patient, the porous layer controls release of the bioactive agent from the at least one layer including the bioactive agent.Type: GrantFiled: August 14, 2002Date of Patent: November 3, 2009Assignee: Cook IncorporatedInventors: Brian L. Bates, Anthony O. Ragheb, Neal E. Fearnot, Thomas G. Kozma, William D. Voorhees, III
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Patent number: 7550005Abstract: A coated implantable medical device 10 includes a structure 12 adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract; at least one coating layer 16 posited on one surface of the structure; and at least one layer 18 of a bioactive material posited on at least a portion of the coating layer 16, wherein the coating layer 16 provides for the controlled release of the bioactive material from the coating layer. In addition, at least one porous layer 20 can be posited over the bioactive material layer 18, wherein the porous layer includes a polymer and provides for the controlled release of the bioactive material therethrough. Preferably, the structure 12 is a coronary stent. The porous layer 20 includes a polymer applied preferably by vapor or plasma deposition and provides for a controlled release of the bioactive material.Type: GrantFiled: August 14, 2002Date of Patent: June 23, 2009Assignee: Cook IncorporatedInventors: Brian L. Bates, Anthony O. Ragheb, Neal E. Fearnot, Thomas G. Kozma, William D. Voorhees, III
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Publication number: 20090157169Abstract: A multiple-sided medical device comprises a frame comprising wire or other resilient material and having a series of bends and interconnecting sides. The device has both a flat configuration and a second, folded configuration which a generally serpentine shape. The device is pushed from a delivery catheter into the lumen of a duct or vessel and may include one or more barbs for anchoring purposes. A full or partial covering of fabric or other flexible material such as DACRON, PTFE, or a collagen-based material such as small intestinal submucosa (SIS), may be sutured or attached to the frame using heat or pressure welding crimping, adhesive, or other techniques to form an occlusion device, a stent graft, or an implantable, intraluminal valve such as for correcting incompetent veins in the lower legs and feet.Type: ApplicationFiled: February 26, 2009Publication date: June 18, 2009Inventors: Dusan Pavcnik, Frederick S. Keller, Josef Rosch, Thomas A. Osborne, Brian L. Bates, Christopher G. Dixon, Andrew K. Hoffa, Raymond B. Leonard, II, Joseph F. Obermiller, John A. DeFord, Joseph W. Roberts
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Publication number: 20090136560Abstract: A coated medical device (10) including a structure (12) adapted for introduction into a passage or vessel of a patient. The structure is formed of preferably a non-porous base material (14) having a bioactive material layer (18) disposed thereon. The medical device is preferably an implantable stent or balloon (26) of which the bioactive material layer is deposited thereon. The stent can be positioned around the balloon and another layer of the bioactive material posited over the entire structure and extending beyond the ends of the positioned stent. The ends of the balloon extend beyond the ends of the stent and include the bioactive material thereon for delivering the bioactive material to the cells of a vessel wall coming in contact therewith. The balloon further includes a layer of hydrophilic material (58) positioned between the base and bioactive material layers of the balloon.Type: ApplicationFiled: January 26, 2009Publication date: May 28, 2009Inventors: Brian L. Bates, Anthony O. Ragheb, Joseph M. Stewart, IV, William J. Bourdeau, Brian D. Choules, James D. Purdy, Neal E. Fearnot
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Patent number: 7520894Abstract: A multiple-sided medical device comprises a frame comprising wire or other resilient material and having a series of bends and interconnecting sides. The device has both a flat configuration and a second, folded configuration which a generally serpentine shape. The device is pushed from a delivery catheter into the lumen of a duct or vessel and may include one or more barbs for anchoring purposes. A full or partial covering of fabric or other flexible material such as DACRON, PTFE, or a collagen-based material such as small intestinal submucosa (SIS), may be sutured or attached to the frame using heat or pressure welding crimping, adhesive, or other techniques to form an occlusion device, a stent graft, or an implantable, intraluminal valve such as for correcting incompetent veins in the lower legs and feet.Type: GrantFiled: June 22, 2005Date of Patent: April 21, 2009Assignees: Cook Incorporated, Cook Biotech Incorporated, Oregon Health & Science UniversityInventors: Dusan Pavcnik, Frederick S. Keller, Josef Rosch, Thomas A. Osborne, Brian L. Bates, Christopher G. Dixon, Andrew K. Hoffa, Raymond B. Leonard, II, Joseph F. Obermiller, John A. DeFord, Joseph W. Roberts
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Publication number: 20090082851Abstract: The present invention provides a wire guide having a variable stiffness region that may be selectively adjusted to vary the stiffness along a portion of the wire guide. The wire guide generally comprises an outer core member and an inner core member, wherein the inner core member is disposed for longitudinal movement with respect to the outer core member. The outer core member is attached to a proximal end of a coiled member, while the inner core member is attached to the coiled member at an attachment region between proximal and distal ends of the coiled member. In operation, distal advancement of the outer core member with respect to the inner core member causes the coiled member to compress at a location between the proximal end of the coiled member and the attachment region, thereby selectively increasing the stiffness along a portion of the length of the wire guide.Type: ApplicationFiled: September 25, 2007Publication date: March 26, 2009Applicant: Cook IncorporatedInventors: John A. Brumleve, Brian L. Bates
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Publication number: 20090069758Abstract: Described are methods, devices, and systems for occluding or ablating vascular vessels. Noninvasive procedures can be used to occlude and obliterate the greater saphenous vein, for example in the treatment of varicose vein condition caused by venous valve insufficiency. Further described is the cooperative use of an angiogenic remodelable material with one or more sclerosing agents to cause closure of a targeted bodily vessel.Type: ApplicationFiled: September 12, 2008Publication date: March 12, 2009Inventors: Brian L. Bates, Ram H. Paul, Jacob A. Flagle
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Publication number: 20090048662Abstract: A multiple-sided medical device comprises a frame comprising wire or other resilient material and having a series of bends and interconnecting sides. The device has both a flat configuration and a second, folded configuration which a generally serpentine shape. The device is pushed from a delivery catheter into the lumen of a duct or vessel and may include one or more barbs for anchoring purposes. A full or partial covering of fabric or other flexible material such as DACRON, PTFE, or a collagen-based material such as small intestinal submucosa (SIS), may be sutured or attached to the frame to form an occlusion device, a stent graft, or an implantable, intraluminal valve such as for correcting incompetent veins in the lower legs and feet.Type: ApplicationFiled: October 27, 2008Publication date: February 19, 2009Inventors: Dusan Pavcnik, Frederick S. Keller, Josef Rosch, Thomas A. Osborne, Brian L. Bates, John A. DeFord, Christopher G. Dixon, Andrew K. Hoffa, Raymond B. Leonard, II, Joseph F. Obermiller
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Patent number: 7452371Abstract: A multiple-sided medical device comprises a frame comprising wire or other resilient material and having a series of bends and interconnecting sides. The device has both a flat configuration and a second, folded configuration which a generally serpentine shape. The device is pushed from a delivery catheter into the lumen of a duct or vessel and may include one or more barbs for anchoring purposes. A full or partial covering of fabric or other flexible material such as DACRON, PTFE, or a collagen-based material such as small intestinal submucosa (SIS), may be sutured or attached to the frame to form an occlusion device, a stent graft, or an implantable, intraluminal valve such as for correcting incompetent veins in the lower legs and feet.Type: GrantFiled: February 5, 2001Date of Patent: November 18, 2008Assignees: Cook Incorporated, Oregon Health & Science University, Cook Biotech, Inc.Inventors: Dusan Pavcnik, Frederick S. Keller, Josef Rosch, Thomas A. Osborne, Brian L. Bates, Christopher G. Dixon, Andrew K. Hoffa, Raymond B. Leonard, II, Joseph F. Obermiller, John A. DeFord, Joseph W. Roberts
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Patent number: 7445628Abstract: Methods of making coated implantable medical devices are provided. The methods include positioning a first layer comprising a bioactive on at least a portion of a structure, and positioning at least one porous layer over the first layer. The at least one porous layer has a thickness adequate to provide a controlled release of the bioactive.Type: GrantFiled: April 14, 2003Date of Patent: November 4, 2008Assignees: Cook Incorporated, MED Institute, Inc.Inventors: Anthony O. Ragheb, Neal E. Fearnot, William D. Voorhees, III, Thomas G. Kozma, Brian L. Bates, Thomas A. Osborne
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Publication number: 20080215138Abstract: A coated implantable medical device 10 includes a structure 12 adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract; at least one coating layer 16 posited on one surface of the structure; and at least one layer 18 of a bioactive material posited on at least a portion of the coating layer 16, wherein the coating layer 16 provides for the controlled release of the bioactive material from the coating layer. In addition, at least one porous layer 20 can be posited over the bioactive material layer 18, wherein the porous layer includes a polymer and provides for the controlled release of the bioactive material therethrough. Preferably, the structure 12 is a coronary stent. The porous layer 20 includes a polymer applied preferably by vapor or plasma deposition and provides for a controlled release of the bioactive material.Type: ApplicationFiled: October 31, 2007Publication date: September 4, 2008Inventors: Brian L. Bates, Anthony O. Ragheb, Neal E. Fearnot, Thomas G. Kozma, William D. Voorhees
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Patent number: 7410665Abstract: A coated implantable medical device 10 includes a structure 12 adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract; at least one coating layer 16 posited on one surface of the structure; and at least one layer 18 of a bioactive material posited on at least a portion of the coating layer 16, wherein the coating layer 16 provides for the controlled release of the bioactive material from the coating layer. In addition, at least one porous layer 20 can be posited over the bioactive material layer 18, wherein the porous layer includes a polymer and provides for the controlled release of the bioactive material therethrough. Preferably, the structure 12 is a coronary stent. The porous layer 20 includes a polymer applied preferably by vapor or plasma deposition and provides for a controlled release of the bioactive material.Type: GrantFiled: June 17, 2004Date of Patent: August 12, 2008Assignees: Cook Incorporated, MED Institute, Inc.Inventors: Anthony O. Ragheb, Brian L. Bates, Neal E. Fearnot, Thomas G. Kozma, William D. Voorhees, III, Anthony H. Gershlick
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Publication number: 20080188892Abstract: A vascular occlusion device for occluding a body cavity. The device includes an elongate flexible member having a proximal portion extending to a distal portion and a radially compressible substance being disposed therebetween. The substance is configured to promote growth of body tissue and may include an extracellular matrix such as small intestine submucosa. The proximal and distal end portions are anchored to the cavity walls such that the position of the substance within the body cavity promotes the growth of body tissue to occlude the body cavity. In one example, the body cavity includes a patent foramen ovale.Type: ApplicationFiled: January 30, 2008Publication date: August 7, 2008Applicant: COOK INCORPORATEDInventors: BRIAN L. BATES, Carlos E. Ruiz, Christopher L. Hruska, Kurt J. Tekulve, Ram H. Paul
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Publication number: 20080183268Abstract: A coated implantable medical device 10 includes a structure 12 adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract; at least one coating layer 16 posited on one surface of the structure; and at least one layer 18 of a bioactive material posited on at least a portion of the coating layer 16, where the coating layer 16 provides for the controlled release of the bioactive material from the coating layer. In addition, at least one porous layer 20 may be posited over the bioactive material layer 18, where the porous layer includes a polymer and provides for the controlled release of the bioactive material therethrough. Preferably, the structure 12 is a coronary stent. The porous layer 20 includes a polymer applied preferably by vapor or plasma deposition and provides for a controlled release of the bioactive material.Type: ApplicationFiled: December 27, 2007Publication date: July 31, 2008Applicants: Cook Incorporated, MED Institute, Inc.Inventors: Brian L. Bates, Anthony O. Ragheb, Neal E. Fearnot, William D. Voorhees, Thomas G. Kozma, David D. Grewe, Darin G. Schaeffer, JiChao Sun
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Publication number: 20080181950Abstract: A biofilm-inhibiting medical product includes a carrier formed from a natural, bioremodelable material, whereby the carrier includes a biocidal bismuth thiol agent and/or one or more other biofilm-inhibiting or wound healing agents. A method for using the biofilm-inhibiting medical product to treat a wound or tissue defect in a patient's body is described.Type: ApplicationFiled: January 24, 2008Publication date: July 31, 2008Applicants: Cook Incorporated, Cook Biotech IncorporatedInventors: Brian L. Bates, Michael C. Hiles, Chad E. Johnson