Patents by Inventor Brian Lee Buckwalter

Brian Lee Buckwalter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of chiral isofluoroenes
    Patent number: 6770463
    Abstract: There is provided a process for the preparation of a chiral insecticidal and acaricidal compound of formula I. Also provided are intermediate compounds useful in the process of the present invention.
    Type: Grant
    Filed: August 2, 2001
    Date of Patent: August 3, 2004
    Assignee: BASF Aktiengesellschaft
    Inventors: John Francis Chiarello, Brian Lee Buckwalter, Timothy Claude Barden
  • Process for the preparation of chiral isofluoroenes
    Publication number: 20020032351
    Abstract: There is provided a process for the preparation of a chiral insecticidal and acaricidal compound of formula I.
    Type: Application
    Filed: August 2, 2001
    Publication date: March 14, 2002
    Applicant: BASF Aktiengesellschaft
    Inventors: John Francis Chiarello, Brian Lee Buckwalter, Timothy Claude Barden
  • Acaricidal and insecticidal substituted pyrimidines and a process for the preparation thereof
    Patent number: 6281219
    Abstract: The present invention provides compounds of Formula I methods for their preparation and their use as acaricidal and insecticidal agents.
    Type: Grant
    Filed: July 12, 1999
    Date of Patent: August 28, 2001
    Assignee: American Cyanamid Co.
    Inventors: Salvatore John Cuccia, William Wakefield Wood, Brian Lee Buckwalter, John Francis Chiarello, Linda Barbara Fleming
  • 2-aryl-&Dgr;2-1,3,4-(oxa and thia)diazoline insecticidal and acaricidal agents
    Patent number: 6235762
    Abstract: The present invention relates to 2-aryl-&Dgr;2-1,3,4-(oxa and thia)diazoline compounds having the structural formula and compositions and methods comprising those compounds for the control of insect and acarid pests.
    Type: Grant
    Filed: November 5, 1999
    Date of Patent: May 22, 2001
    Assignee: American Cyanamid Company
    Inventors: James Jan Takasugi, Brian Lee Buckwalter
  • Stabilization of fibroblast growth factors by modification of cysteine residues
    Patent number: 6010999
    Abstract: The present invention relates to physiologically-active derivatized natural and recombinant mammalian and human proteins and polypeptides. The invention provides chemical methods for derivatizing natural and recombinantly-derived proteins or polypeptides containing cysteine residues, either naturally or through site specific mutageneses. The pharmaceutical compositions containing said derivatized proteins and/or polypeptides are formulated to provide stable, long-acting compositions of such proteins and/or polypeptides, previously difficult to achieve.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: January 4, 2000
    Assignee: American Cyanamid Company
    Inventors: Michael Joseph Daley, Brian Lee Buckwalter, Susan Mancini Cady, Hong-Ming Shieh, Peter Bohlen, Andrew P. Seddon
  • Process and intermediate compounds for the preparation of pesticidal fluoroolefin compounds
    Patent number: 5973190
    Abstract: The present invention provides a process for the preparation of pesticidal fluoroolefin compounds having the structural formula I ##STR1## The present invention also provides intermediate compounds which are utilized in the process of this invention.
    Type: Grant
    Filed: June 18, 1998
    Date of Patent: October 26, 1999
    Assignee: American Cyanamid Company
    Inventors: Brian Lee Buckwalter, Timothy Claude Barden
  • Stabilization of somatotropins and other proteins by modification of cysteine residues
    Patent number: 5951972
    Abstract: The present invention relates to physiologically-active derivatized natural and recombinant mammalian and human proteins and polypeptides. The invention provides chemical methods for derivatizing natural and recombinantly-derived proteins or polypeptides containing cysteine residues, either naturally or through site specific mutageneses. The pharmaceutical compositions containing the derivatized proteins and/or polypeptides are formulated to provide stable, long-acting compositions of such proteins and/or polypeptides, previously difficult to achieve.
    Type: Grant
    Filed: February 6, 1995
    Date of Patent: September 14, 1999
    Assignee: American Cyanamid Company
    Inventors: Michael Joseph Daley, Brian Lee Buckwalter, Susan Mancini Cady, Hong-Ming Shieh, Peter Bohlen, Andrew P. Seddon
  • Stabilization of somatotropins by modification of cysteine residues utilizing site directed mutagenesis
    Patent number: 5891840
    Abstract: Novel modified or derivatized recombinant animal somatotropins. Methods for stabilizing recombinant animal somatotropins by modification or deletion of the Cysteine residues utilizing site directed mutagenesis to replace from one to four of the cysteine amino acid residues of said somatotropins with one or more different amino acid residues or by derivatization of (1) both cysteine amino acid residues in the small loop of said somatotropin, both cysteine amino acid residues in the large loop or the four cysteine amino acid residues in both loops of said somatotropin.
    Type: Grant
    Filed: May 9, 1995
    Date of Patent: April 6, 1999
    Assignee: American Cyanamid Company
    Inventors: Susan Mancini Cady, John Steele Logan, Brian Lee Buckwalter, Gerald William Stockton, Deborah Tardy Chaleff
  • Pure somatostatin antagonist and methods of use thereof
    Patent number: 5846934
    Abstract: A method for decreasing the effect of somatostatin. A peptide of formula I which is a pure somatostatin antagonist, methods for increasing the release of growth hormone, insulin and glucagon in mammals, and a method for the enhancement of growth in mammals are also described.
    Type: Grant
    Filed: February 19, 1997
    Date of Patent: December 8, 1998
    Assignee: American Cyanamid Company
    Inventors: Roy Tyson Bass, Brian Lee Buckwalter, John Richard Hadcock, Bomi Pilloo Patel, John Francis Chiarello
  • 9-[(substituted glycyl)amido]-6-(substituted)-5-hydroxy-6-deoxytetracyclines
    Patent number: 5639742
    Abstract: The invention provides compounds of the formula: ##STR1## wherein R, R.sup.1, R.sup.2 and W are defined in the specification. These compounds are useful as antibiotic agents.
    Type: Grant
    Filed: August 29, 1994
    Date of Patent: June 17, 1997
    Inventors: Ving Jick Lee, Brian Lee Buckwalter, Timothy Claude Barden