Abstract: A door assembly for selectively interlocking opposing doors each pivotably mounted at a hinge side thereof to a door frame so as to both open and close in the same direction includes a door handle assembly mounted to one door at a latch side thereof opposite the hinge side and carrying a first plurality of magnets, and another door handle assembly mounted to the other door at a latch side thereof opposite the hinge side and carrying a second plurality of magnets. The door handle assemblies are arranged relative to each other with the first and second pluralities of magnets aligned such each aligned pair of the first and second pluralities of magnets have opposite magnetic polarities, and the aligned first and second pluralities of magnets magnetically couple to each other as the door handle assemblies are brought into contact with each other.

Abstract: The present invention is a device for installing and removing partially obstructed, upward-facing lightbulbs. It is comprised of a gripping element, a weight, a flexible rotary shaft having two ends, and an extension pole having two ends. The gripping element, itself, is comprised of a hollow, three-dimensional gripping element body having an inner and outer surface and a plurality of flexible, tactile members. The hollow, three-dimensional gripping element body is open at one end and closed at the other. At the open end, the plurality of flexible, tactile members are arranged about a peripheral rim at the opening. When the device is placed over a lightbulb, the flexible, tactile members capture the lightbulb. Rotating the extension pole will cause the lightbulb to rotate.

Abstract: Some embodiments provide narrative feedback generator that assists a user in composing narrative feedback paragraphs. In one embodiment, a method stores sentences associated with a plurality of performance levels and with one of a plurality of feedback element tiers and links sentences between different tiers. The method also receives a selection of an output document type and an individual of the output document. The method then filters for a first set of sentences associated with a first tier in the hierarchy and presents the first set of sentences to the user and receives a selection of a first sentence in the first set of sentences. Additionally, the method filters for a second set of sentences that are associated both with a second tier in the hierarchy and linked to the first sentence and presenting the second set of sentences to the user and receives a selection of a second sentence in the second set of sentences. The method then generates a paragraph comprising the first and second sentences.

Abstract: Disclosed herein are TLR-agonists compounds, antibody-TLR agonist conjugates, pharmaceutical composition, and methods of use of such compounds or conjugates as therapeutics for treating a disease or condition such as cancer.

Abstract: Disclosed herein, inter alia, are methods of making polyketide compounds.

Abstract: Disclosed herein are Trastuzumab-linked TLR-agonist derivative analogs that include at least one non-natural amino acid, and methods for making such non-natural amino acids and polypeptides. The Trastuzumab-linked TLR-agonist derivative analogs can include a wide range of possible functionalities, but typically have at least one oxime, carbonyl, dicarbonyl, and/or hydroxylamine group. Also disclosed herein are non-natural amino acid Trastuzumab-linked TLR-agonist derivative analogs that are further modified post-translationally, methods for effecting such modifications, and methods for purifying such Trastuzumab-linked TLR-agonist derivative analogs. Typically, the modified Trastuzumab-linked TLR-agonist derivative analogs include at least one oxime, carbonyl, dicarbonyl, and/or hydroxylamine group.

Abstract: There are provided inter alia stable anti-cancer compounds and splice modulators and methods of synthesis and use thereof.

Abstract: A photonic bandgap antenna (PBA) (10') utilizes a periodic bandgap material (PBM), which is essentially a dielectric, to transmit, receive, or communicate electromagnetic radiation encoded with information. Further, a photonic bandgap transmission line (PBTL) (10") can also be constructed with the PBM. Because the PBA (10') and PBTL (10") do not utilize metal, the PBA (10') and PBTL (10") can be used in harsh environments, such as those characterized by high temperature and/or high pressure, and can be easily built into a dielectric structure such as a building wall or roof. Further, the PBA (10') and PBTL (10") inhibit scattering by incident electromagnetic radiation at frequencies outside those electromagnetic frequencies in the bandgap range associated with the PBM.