Abstract: The invention relates to imidazopyridines of Formula (I) and pharmaceutically acceptable salts thereof, wherein R0 to R5 are as defined in the description; to their use in medicine; to compositions containing them; to processes for their preparation; and to intermediates used in such processes. The benzimidazoles of Formula (I) are ITK inhibitors and are therefore potentially useful in the treatment of a wide range of disorders including, atopic dermatitis.

Abstract: In one example, an optoelectronic module may include a stack assembly including an electrical integrated circuit and an optical integrated circuit electrically and mechanically coupled to one another, an interposer electrically and mechanically coupled to the stack assembly, and an optical connector to optically couple the optical integrated circuit with an array of optical fibers.

Abstract: Systems and methods for authenticating access to multiple data stores substantially in real-time are disclosed. The system may include a server coupled to a network, a client device in communication with the server via the network and a plurality of data stores. The server may authenticate access to the data stores and forward information from those stores to the client device. An exemplary authentication method may include receipt of a request for access to data. Information concerning access to that data is stored and associated with an identifier assigned to a client device. If the identifier is found to correspond to the stored information during a future request for access to the store, access to that store is granted.

Abstract: A computer-implemented method includes determining a number of distance points connected to a person at a point in time, scraping a plurality of indexes corresponding to a respective plurality of journey hosts to identify a plurality of journey possibilities for each journey host of the plurality of journey hosts, generating a plurality of reachable locations based on the number of distance points and the journey possibilities, the plurality of reachable locations comprising at least a subset of the plurality of journey possibilities correlated to the number of distance points, receiving location signals generated via a location sensor of a device associated with the person, identifying one or more previous locations of the device based on the location signals, identifying a subset of the reachable locations based on the previous locations of the device, and generating a graphical interface to visually display the subset of the reachable locations on a map.

Abstract: A method for categorizing a viral risk within a occupiable space, the method comprising the steps of: measuring environmental data using a plurality of sensors within said occupiable space; determining a virus index for the occupiable space based upon a combination of said environmental data; providing a virus index scale, said scale including environmental categories corresponding to different viral indices; comparing the virus index with the virus index scale, and so; categorizing the viral risk of the occupiable space.

Abstract: In some implementations, a device, using a browser extension of a browser application, may obtain the data from an application using a private endpoint of the application. The private endpoint of the application may be accessible via a private network in which the browser application is implemented and may not be accessible via a public network. The device, using the browser extension of the browser application, may transmit, to the cloud-based service, the data to cause the cloud-based service to populate a document with the data.

Abstract: A computer-implemented method includes determining a number of distance points connected to a person at a point in time, scraping a plurality of indexes corresponding to a respective plurality of journey hosts to identify a plurality of journey possibilities for each journey host of the plurality of journey hosts, generating a plurality of reachable locations based on the number of distance points and the journey possibilities, the plurality of reachable locations comprising at least a subset of the plurality of journey possibilities correlated to the number of distance points, receiving location signals generated via a location sensor of a device associated with the person, identifying one or more previous locations of the device based on the location signals, identifying a subset of the reachable locations based on the previous locations of the device, and generating a graphical interface to visually display the subset of the reachable locations on a map.

Abstract: The invention encompasses a nontoxic agricultural formulation of a concentrated liquid suspension comprising a drying oil and suspended particulate materials further comprising an additional material; and also encompasses an aqueous formulation comprising the concentrated liquid suspension and an agricultural treatment agent. The invention additionally encompasses methods of treating an agricultural target.

Abstract: In some implementations, a device, using a browser extension of a browser application, may obtain the data from an application using a private endpoint of the application. The private endpoint of the application may be accessible via a private network in which the browser application is implemented and may not be accessible via a public network. The device, using the browser extension of the browser application, may transmit, to the cloud-based service, the data to cause the cloud-based service to populate a document with the data.

Abstract: A computer-implemented method includes determining a number of distance points connected to a person at a point in time, scraping a plurality of indexes corresponding to a respective plurality of journey hosts to identify a plurality of journey possibilities for each journey host of the plurality of journey hosts, generating a plurality of reachable locations based on the number of distance points and the journey possibilities, the plurality of reachable locations comprising at least a subset of the plurality of journey possibilities correlated to the number of distance points, receiving location signals generated via a location sensor of a device associated with the person, identifying one or more previous locations of the device based on the location signals, identifying a subset of the reachable locations based on the previous locations of the device, and generating a graphical interface to visually display the subset of the reachable locations on a map.

Abstract: The invention encompasses a nontoxic agricultural formulation of a concentrated liquid suspension comprising a drying oil and suspended particulate materials, and also encompasses an aqueous formulation comprising the concentrated liquid suspension and an agricultural treatment agent. The invention additionally encompasses methods of treating an agricultural target.

Abstract: A crosslinked self-assembled monolayer (SAM), comprising surface groups containing a nitrogen-heterocycle, was formed on an oxygen plasma-treated silicon oxide or hafnium oxide top surface of a substrate. The SAM is covalently bound to the underlying oxide layer. The SAM was patterned by direct write methods using ultraviolet (UV) light of wavelength 193 nm or an electron beam, forming a line-space pattern comprising non-exposed SAM features. The non-exposed SAM features non-covalently bound DNA-wrapped carbon nanotubes (DNA-CNT) deposited from aqueous solution with a selective placement efficiency of about 90%. Good alignment of carbon nanotubes to the long axis of the SAM features was also observed. The resulting patterned biopolymer features were used to prepare a CNT based field effect transistor.

Abstract: Cleaning articles including a heat engine incorporated therein. The cleaning article may include a substrate (e.g., a non-woven wipe) including one or more layers. The heat engine may be in the wipe or pad, and includes a reactive metal composition which upon contact with a salt water (e.g., saline) composition, reacts to produce heat. The cleaning article may thus produce water vapor and/or steam upon activation of the heat engine. A venting structure may be provided adjacent to or surrounding the heat engine that includes an impermeable material (e.g., impermeable to water and/or air or other gas), which includes one or more vents through the impermeable material. The venting structure directs water vapor and/or steam to a desired face of the cleaning article, away from the user. A heat barrier layer may insulate a user's hand from the generated heat, and/or a handle may be attachable to the pad.

Abstract: A crosslinked self-assembled monolayer (SAM), comprising surface groups containing a nitrogen-heterocycle, was formed on an oxygen plasma-treated silicon oxide or hafnium oxide top surface of a substrate. The SAM is covalently bound to the underlying oxide layer. The SAM was patterned by direct write methods using ultraviolet (UV) light of wavelength 193 nm or an electron beam, forming a line-space pattern comprising non-exposed SAM features. The non-exposed SAM features non-covalently bound DNA-wrapped carbon nanotubes (DNA-CNT) deposited from aqueous solution with a selective placement efficiency of about 90%. Good alignment of carbon nanotubes to the long axis of the SAM features was also observed. The resulting patterned biopolymer features were used to prepare a CNT based field effect transistor.

Abstract: Cleaning articles including a heat engine incorporated therein. The cleaning article may include a substrate (e.g., a non-woven wipe) including one or more layers. The heat engine may be in the wipe or pad, and includes a reactive metal composition which upon contact with a salt water (e.g., saline) composition, reacts to produce heat. The cleaning article may thus produce water vapor and/or steam upon activation of the heat engine. A venting structure may be provided adjacent to or surrounding the heat engine that includes an impermeable material (e.g., impermeable to water and/or air or other gas), which includes one or more vents through the impermeable material. The venting structure directs water vapor and/or steam to a desired face of the cleaning article, away from the user. A heat barrier layer may insulate a user's hand from the generated heat, and/or a handle may be attachable to the pad.

Abstract: Cleaning articles including a heat engine incorporated therein. The cleaning article may include a substrate (e.g., a non-woven wipe) including one or more layers. The heat engine may be in the wipe or pad, and includes a reactive metal oxide which upon contact with water, reacts to produce heat. The cleaning article may thus produce water vapor and/or steam upon activation of the heat engine. A venting structure may be provided adjacent to or surrounding the heat engine that includes an impermeable material (e.g., impermeable to water and/or air or other gas), which includes one or more vents through the impermeable material. The venting structure directs water vapor and/or steam to a desired face of the cleaning article, away from the user. A heat barrier layer may insulate a user's hand from the generated heat, and/or a handle may be attachable to the pad.

Abstract: Cleaning articles including a heat engine incorporated therein. The cleaning article may include a substrate (e.g., a non-woven wipe) including one or more layers. The heat engine may be in the wipe or pad, and includes a reactive metal composition which upon contact with a salt water (e.g., saline) composition, reacts to produce heat. The cleaning article may thus produce water vapor and/or steam upon activation of the heat engine. A venting structure may be provided adjacent to or surrounding the heat engine that includes an impermeable material (e.g., impermeable to water and/or air or other gas), which includes one or more vents through the impermeable material. The venting structure directs water vapor and/or steam to a desired face of the cleaning article, away from the user. A heat barrier layer may insulate a user's hand from the generated heat, and/or a handle may be attachable to the pad.

Abstract: Cleaning articles including a heat engine incorporated therein. The cleaning article may include a substrate (e.g., a non-woven wipe) including one or more layers. The heat engine may be in the wipe or pad, and includes a reactive metal oxide which upon contact with water, reacts to produce heat. The cleaning article may thus produce water vapor and/or steam upon activation of the heat engine. A venting structure may be provided adjacent to or surrounding the heat engine that includes an impermeable material (e.g., impermeable to water and/or air or other gas), which includes one or more vents through the impermeable material. The venting structure directs water vapor and/or steam to a desired face of the cleaning article, away from the user. A heat barrier layer may insulate a user's hand from the generated heat, and/or a handle may be attachable to the pad.

Abstract: A direct-type LED backlight module includes a back bezel having opposite first and second surfaces, a daughterboard having opposite third and fourth surfaces, LED lightbars disposed on the first surface, and a local dimming control board disposed on the second surface. The first surface has a groove disposed thereon. The second surface has a through hole disposed thereon and communicating with the groove. The daughterboard is disposed in the groove. The third surface has first connectors disposed thereon and protruding out the groove. The fourth surface has a second connector disposed thereon and protruding out the second surface through the through hole. The first and second connectors are electrically connected. Each LED lightbar has a third connector disposed thereon and connected to the corresponding first connector. The local dimming control board has a fourth connector disposed thereon and connected to the second connector. It reduces wiring cost and assembly time.

Abstract: A direct-type LED backlight module includes a back bezel having opposite first and second surfaces, a daughterboard having opposite third and fourth surfaces, LED lightbars disposed on the first surface, and a local dimming control board disposed on the second surface. The first surface has a groove disposed thereon. The second surface has a through hole disposed thereon and communicating with the groove. The daughterboard is disposed in the groove. The third surface has first connectors disposed thereon and protruding out the groove. The fourth surface has a second connector disposed thereon and protruding out the second surface through the through hole. The first and second connectors are electrically connected. Each LED lightbar has a third connector disposed thereon and connected to the corresponding first connector. The local dimming control board has a fourth connector disposed thereon and connected to the second connector. It reduces wiring cost and assembly time.