Patents by Inventor Brian M. FREED

Brian M. FREED has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230047491
    Abstract: The present invention relates to a method of transporting a stem cell population, the method comprising transporting the stem cell population contacted with a liquid carrier. In addition, the present invention concerns a method of treating a subject having a disease, the method comprising topically administering a defined mesenchymal stem cell population to the subject, wherein the mesenchymal stem cell population is administered within about 96 hours from the time point the mesenchymal stem cell population has been harvested. Also concerned is a unit dosage comprising about 20 million cells, of about 15 million cells, of about 10 million cells, of about 5 million cells, of about 4 million cells, of about 3 million cells, of about 2 million cells, of about 1 million cells, of about 0.5 million cells, of about 0.25 million cells or of less than 0.25 million cells of a defined mesenchymal stem cell population.
    Type: Application
    Filed: August 1, 2022
    Publication date: February 16, 2023
    Applicant: Cellresearch Corporation Pte. Ltd.
    Inventors: Toan Thang PHAN, Brian M. FREED
  • Patent number: 11400119
    Abstract: The present invention relates to a method of transporting a stem cell population, the method comprising transporting the stem cell population contacted with a liquid carrier. In addition, the present invention concerns a method of treating a subject having a disease, the method comprising topically administering a defined mesenchymal stem cell population to the subject, wherein the mesenchymal stem cell population is administered within about 96 hours from the time point the mesenchymal stem cell population has been harvested. Also concerned is a unit dosage comprising about 20 million cells, of about 15 million cells, of about 10 million cells, of about 5 million cells, of about 4 million cells, of about 3 million cells, of about 2 million cells, of about 1 million cells, of about 0.5 million cells, of about 0.25 million cells or of less than 0.25 million cells of a defined mesenchymal stem cell population.
    Type: Grant
    Filed: April 9, 2019
    Date of Patent: August 2, 2022
    Assignee: Cellresearch Corporation Pte. Ltd.
    Inventors: Toan Thang Phan, Brian M. Freed
  • Publication number: 20210102171
    Abstract: The present invention relates to a mesenchymal stem cell storing or transport formulation, a method of preparing the mesenchymal stem cell toring or transport formulation as well as to methods of using the mesenchymal stem cell storing or transport formulation. Such methods include a method of transporting mesenchymal stem cells in this storing or transport formulation as well as a method of treating a subject having a disease, the method comprising topically administering mesenchymal stem cells that have been stored or transported in this storing or transport formulation. Also concerned is a unit dosage of the mesenchymal stem cells.
    Type: Application
    Filed: October 8, 2020
    Publication date: April 8, 2021
    Applicants: CELLRESEARCH CORPORATION PTE. LTD., THE REGENTS OF THE UNIVERSITY OF COLORADO
    Inventors: Toan Thang PHAN, Brian M. FREED
  • Publication number: 20190307805
    Abstract: The present invention relates to a method of transporting a stem cell population, the method comprising transporting the stem cell population contacted with a liquid carrier. In addition, the present invention concerns a method of treating a subject having a disease, the method comprising topically administering a defined mesenchymal stem cell population to the subject, wherein the mesenchymal stem cell population is administered within about 96 hours from the time point the mesenchymal stem cell population has been harvested. Also concerned is a unit dosage comprising about 20 million cells, of about 15 million cells, of about 10 million cells, of about 5 million cells, of about 4 million cells, of about 3 million cells, of about 2 million cells, of about 1 million cells, of about 0.5 million cells, of about 0.25 million cells or of less than 0.25 million cells of a defined mesenchymal stem cell population.
    Type: Application
    Filed: April 9, 2019
    Publication date: October 10, 2019
    Applicants: Cellresearch Corporation Pte. Ltd., The Regents of the University of Colorado
    Inventors: Toan Thang PHAN, Brian M. FREED