Abstract: Tamper-evident plastic container comprises a base portion having a sidewall and a base flange extending outwardly from at least a portion of the sidewall, and a lid portion having a lid tab joined to the base flange by a hinge, wherein the lid portion has an open position and a closed position. The lid portion is configured to lockingly engage the base portion in the closed position. One of the base flange or the lid tab has a non-linear path of weakness formed therein to define a frangible connection, wherein the frangible connection is configured to be ruptured to initially open the lid portion from the closed position. The non-linear path of weakness is spaced from the hinge to define a tamper indicator region between the non-linear path of weakness and the hinge, wherein the tamper indicator region remains joined to the hinge after the frangible connection is ruptured.

Abstract: Tamper-evident plastic container comprises a base portion having a sidewall and a base flange extending outwardly from at least a portion of the sidewall, and a lid portion having a lid tab joined to the base flange by a hinge, wherein the lid portion has an open position and a closed position. The lid portion is configured to lockingly engage the base portion in the closed position. One of the base flange or the lid tab has a non-linear path of weakness formed therein to define a frangible connection, wherein the frangible connection is configured to be ruptured to initially open the lid portion from the closed position. The non-linear path of weakness is spaced from the hinge to define a tamper indicator region between the non-linear path of weakness and the hinge, wherein the tamper indicator region remains joined to the hinge after the frangible connection is ruptured.

Abstract: Tamper-evident plastic container comprises a base portion having a sidewall and a base flange extending outwardly from at least a portion of the sidewall, and a lid portion having a lid tab joined to the base flange by a hinge, wherein the lid portion has an open position and a closed position. The lid portion is configured to lockingly engage the base portion in the closed position. One of the base flange or the lid tab has a non-linear path of weakness formed therein to define a frangible connection, wherein the frangible connection is configured to be ruptured to initially open the lid portion from the closed position. The non-linear path of weakness is spaced from the hinge to define a tamper indicator region between the non-linear path of weakness and the hinge, wherein the tamper indicator region remains joined to the hinge after the frangible connection is ruptured.

Abstract: Tamper-evident plastic container comprises a base portion having a base flange and a lid portion having a lid tab joined to the base flange by a hinge, wherein the lid portion has at least one grip tab extending outwardly beyond the base flange. The lid portion is configured to lockingly engage the base portion in a closed position. One of the base flange or the lid tab has a path of weakness formed therein to define a frangible connection, wherein the frangible connection is configured to be ruptured to initially open the lid portion from the closed position. The path of weakness is spaced from the hinge to define a tamper indicator region between the path of weakness and the hinge, wherein the tamper indicator region remains joined to the hinge after the frangible connection is ruptured. Methods of containing a product in a tamper-evident container are also disclosed.

Abstract: Tamper-evident plastic container comprises a base portion having a sidewall and a base flange extending outwardly from at least a portion of the sidewall, as well as a lid portion having a lid tab joined to the base flange by a hinge, wherein the lid portion has an open position and a closed position. The lid portion is configured to lockingly engage the base portion in the closed position. One of the base flange or the lid tab has a non-linear path of weakness formed therein to define a frangible connection, wherein the frangible connection is configured to be ruptured to initially open the lid portion from the closed position. The non-linear path of weakness is spaced from the hinge to define a tamper indicator region between the non-linear path of weakness and the hinge, wherein the tamper indicator region remains joined to the hinge after the frangible connection is ruptured. Methods of containing a product in a tamper-evident container are also disclosed.

Abstract: Tamper-evident plastic container comprises a base portion having a sidewall and a base flange, and a lid portion having a lid tab joined to the base flange by a hinge, wherein the lid portion has an open and a closed position. The lid portion is configured to lockingly engage the base portion in the closed position. One of the base flange or the lid tab has a non-linear path of weakness formed therein to define a frangible connection, wherein the frangible connection is configured to be ruptured to initially open the lid portion from the closed position. The non-linear path of weakness is spaced from the hinge to define a tamper indicator region between the non-linear path of weakness and the hinge, wherein the tamper indicator region remains joined to the hinge after the frangible connection is ruptured. Methods of containing a product in a tamper-evident container are also disclosed.

Abstract: Tamper-evident plastic container comprises a base portion having a sidewall and a base flange extending outwardly from at least a portion of the sidewall, as well as a lid portion having a lid tab joined to the base flange by a hinge, wherein the lid portion has an open position and a closed position. The lid portion is configured to lockingly engage the base portion in the closed position. One of the base flange or the lid tab has a non-linear path of weakness formed therein to define a frangible connection, wherein the frangible connection is configured to be ruptured to initially open the lid portion from the closed position. The non-linear path of weakness is spaced from the hinge to define a tamper indicator region between the non-linear path of weakness and the hinge, wherein the tamper indicator region remains joined to the hinge after the frangible connection is ruptured. Methods of containing a product in a tamper-evident container are also disclosed.

Abstract: The present application relates to formulations of anti-CD105 antibodies, antigen-binding fragments thereof, and uses thereof. Another aspect relates to pre-filled syringes of the formulations of anti-CD105 antibodies or antigen-binding fragments thereof. Another aspect relates to the use of the formulations to reduce one or more signs or symptoms of an angiogenesis-related disorder such as cancers and ophthalmologic diseases.

Abstract: The present application relates to formulations of anti-CD105 antibodies, antigen-binding fragments thereof, and uses thereof. Another aspect relates to pre-filled syringes of the formulations of anti-CD105 antibodies or antigen-binding fragments thereof. Another aspect relates to the use of the formulations to reduce one or more signs or symptoms of an angiogenesis-related disorder such as cancers and ophthalmologic diseases.

Abstract: The present application relates to formulations of anti-CD105 antibodies, antigen-binding fragments thereof, and uses thereof. Another aspect relates to pre-filled syringes of the formulations of anti-CD105 antibodies or antigen-binding fragments thereof. Another aspect relates to the use of the formulations to reduce one or more signs or symptoms of an angiogenesis-related disorder such as cancers and ophthalmologic diseases.