Abstract: Aspects of the application provide anti-hemojuvelin antibodies and methods of using the same in treating anemias of chronic disease, iron-restricted anemias, and/or conditions associated with anemia.

Abstract: Aspects of the application provide hepcidin antagonists and methods of using the same in treating myelofibrosis and/or conditions associated with myelofibrosis.

Abstract: A textile treatment emulsion formulation includes a silicone-(meth)acrylate copolymer, a surfactant, water and a blocked isocyanate and method for its preparation are disclosed. The textile treatment emulsion may be used in a method including coating the emulsion formulation on a textile and heating the textile to dry the emulsion formulation. This method renders the textile oil repellent.

Abstract: Aspects of the application provide anti-hemojuvelin antibodies and methods of using the same in treating myelofibrosis and/or conditions associated with myelofibrosis.

Abstract: Aspects of the application provide anti-hemojuvelin antibodies and methods of using the same in treating myelofibrosis and/or conditions associated with myelofibrosis.

Abstract: Aspects of the application provide anti-hemojuvelin antibodies and methods of using the same in treating myelofibrosis and/or conditions associated with myelofibrosis.

Abstract: Aspects of the application provide anti-hemojuvelin antibodies and methods of using the same in treating myelofibrosis and/or conditions associated with myelofibrosis.

Abstract: Aspects of the application provide anti-hemojuvelin antibodies and methods of using the same in treating myelofibrosis and/or conditions associated with myelofibrosis.

Abstract: Aspects of the application provide anti-hemojuvelin antibodies and methods of using the same in treating myelofibrosis and/or conditions associated with myelofibrosis.

Abstract: Aspects of the application provide anti-hemojuvelin antibodies and methods of using the same in treating myelofibrosis and/or conditions associated with myelofibrosis.

Abstract: Aspects of the application provide hemojuvelin antagonists and methods of using the same in treating anemias of kidney disease and conditions associated with these anemias. Methods provided in the application relate to treatment of a subject having an anemia associated with chronic kidney disease and/or kidney disease in a subject that has a level of glomerular filtration rate lower than one or more thresholds.

Abstract: The present invention relates to a mining system. The system includes a continuous miner for forming plunge tunnels from a roadway. A flexible conveyor system is coupled to the continuous miner for conveying mined material from the plunge tunnels. A controller is provided for controlling the continuous miner and the flexible conveyor system to travel along a predetermined path. Advantageously, the controller may control the drive and steering (including turning maneuvers) of the continuous miner and each conveyor module of the flexible conveyor system along the predetermined path to avoid striking either any adjacent equipment (e.g., another conveyor), or the “ribs” of a plunge tunnel being mined.

Abstract: The present invention relates to a system for recovering a continuous miner arrangement from a tunnel. The system includes a coupler for coupling the continuous miner arrangement to a pulling apparatus. The pulling apparatus pulls the continuous miner arrangement from the tunnel. Advantageously, the pulling apparatus may pull the continuous miner arrangement from the tunnel, either fully or partially until the continuous miner arrangement may once again retract from the tunnel under its own power.

Abstract: The present invention relates to a mining system. The system includes a continuous miner for forming plunge tunnels from a roadway. A flexible conveyor system is coupled to the continuous miner for conveying mined material from the plunge tunnels. A controller is provided for controlling the continuous miner and the flexible conveyor system to travel along a predetermined path. Advantageously, the controller may control the drive and steering (including turning maneuvers) of the continuous miner and each conveyor module of the flexible conveyor system along the predetermined path to avoid striking either any adjacent equipment (e.g. another conveyor), or the ‘ribs’ of a plunge tunnel being mined.

Abstract: The present invention relates to a mining system. The system includes a continuous miner for forming plunge tunnels from a roadway. A flexible conveyor system is coupled to the continuous miner for conveying mined material from the plunge tunnels. A controller is provided for controlling the continuous miner and the flexible conveyor system to travel along a predetermined path. Advantageously, the controller may control the drive and steering (including turning maneuvers) of the continuous miner and each conveyor module of the flexible conveyor system along the predetermined path to avoid striking either any adjacent equipment (e.g., another conveyor), or the “ribs” of a plunge tunnel being mined.

Abstract: Aspects of the application provide anti-hemojuvelin antibodies and methods of using the same in treating anemias of chronic disease, iron-restricted anemias, and/or conditions associated with anemia.

Abstract: Aspects of the application provide anti-hemojuvelin antibodies and methods of using the same in treating myelofibrosis and/or conditions associated with myelofibrosis.

Abstract: A technique provides cohesive and secure access to management services of a distributed storage architecture deployed on compute and storage nodes of a cluster. The management services are organized as a platform that encompasses a plurality of underlying individual services each having an applications programming interface (API) that are together securely accessible via an API gateway. The gateway is configured to support a “browsable” directory of the APIs that enables a client to identify various underlying services available within the cluster. In an embodiment, the underlying services “self-register” at the gateway to provide a single, unified location for the client to access the services. The API gateway includes a reverse-proxy server that is configured to provide a single point of entry for clients interacting with the individual services underlying the management services platform.

Abstract: The present invention relates to a flexible conveyor system. The system includes a supply conveyor module and a receiver conveyor module. A hitch mechanism is provided for pivotally coupling the supply conveyor module to the receiver conveyor module about a pivot axis so that the receiver conveyor module receives conveyed material from the supply conveyor module proximal to the pivot axis. Advantageously, the receiver conveyor module receives conveyed material from the supply conveyor module proximal to the pivot axis which impedes spillage between the adjacent conveyor modules on very tight corners.

Abstract: Aspects of the application provide hepcidin antagonists and methods of using the same in treating anemias of chronic disease, iron-restricted anemias, and/or conditions associated with anemia. Accordingly, aspects of the present disclosure relate to treating a subject with high hepcidin levels (e.g., ACD) by inhibiting the BMP signaling pathway (e.g., hemojuvelin-induced BMP signaling pathway) and/or the inflammatory response (e.g., IL-6 mediated inflammatory pathway).