Abstract: The invention is a nano-entity conjugate for use in an in vivo immunomagnetic hyperthermia system for the detection and treatment of any cell or virus having a target surface receptor which encompasses a technology platform that can be used for both real-time monitoring of any cell or virus having a target surface receptor and as a delivery platform for certain types of treatment that are conducive for in vivo applications. The system allows of cell or virus enumeration; cell or virus capture; and cell or virus removal from the patient's circulatory system in-vivo using immunomagnetic hyperthermia. The application of immunomagnetic hyperthermia may actually diminish and eventually stop the progression of cancer and other blood borne or blood affected diseases.

Abstract: A system and method for amplifying an information carrying signal provided on electrical supply power are provided. An input amplifier unit receives an input signal which contains an information carrying component and a supply power component. A power conversion unit is coupled to the input amplifier unit. The input amplifier unit amplifies the information carrying component of the input signal to generate an amplified signal. The power conversion unit generates at least one complementary set of offset supply levels each referenced to a non-zero offset ground level adaptively defined responsive to the electrical supply power, such that the amplified signal is referenced about the offset ground level. In certain embodiments, an output conditioning unit is employed to generate an output signal comprising an amplified version of the information carrying component of the input signal extracted from the amplified signal.