Patents by Inventor Brian McGuinness

Brian McGuinness has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250036086
    Abstract: A tempo detection and display system, a musical practice and mastery system, a musical aid, a disc jockey aid, processes, and method of use are presented. The present disclosure is configured to provide measurements and display these measurements, and in particular display via nixie tubes. The measurements configured of and/or interpreting an external audio signal. Additionally, the system is configured to measure and display dB SPL; decibel of sound pressure level, also referred to as “dB SPL”, “decibel of sound pressure level” or “decibel sound pressure level”. To switch what parameter is being displayed, a 3-state toggle switch; or “toggle switch” or “toggle”, which is located on the main body.
    Type: Application
    Filed: July 25, 2024
    Publication date: January 30, 2025
    Inventor: Brian McGuinness
  • Patent number: 12077595
    Abstract: The disclosure relates to CD137 binding agents and the use of such binding agents in the treatment, prevention and detection of disease.
    Type: Grant
    Filed: November 13, 2018
    Date of Patent: September 3, 2024
    Assignee: Crescendo Biologics Limited
    Inventors: Verena Brucklacher-Waldert, Carolyn Edwards, James Legg, Jayesh Majithiya, Brian McGuinness, Christine Rossant, Yumin Teng
  • Publication number: 20240281510
    Abstract: An identification system, a geographic location verification system, a system for verifying an identification in a geographic location, processes of authenticating, and methods of use are presented. The present disclosure utilizes global positioning systems in concert with various biometric information to authenticate the presence of a person in a particular place, at a particular time. More specifically, and without limitation, the present system authenticates location of a person in a given place at a given time for validation, authentication, and verification to be used by others and/or provided to others for use in verifying percentages of time spent in a plurality of locations. This may be a particular date, particular time period, or percentage in a particular place.
    Type: Application
    Filed: February 17, 2024
    Publication date: August 22, 2024
    Inventors: Luke McGuinness, Brian McGuinness
  • Publication number: 20240199731
    Abstract: Binding molecules to IL-17A. The binding molecules are useful in the treatment of disorders, for example psoriasis.
    Type: Application
    Filed: April 26, 2023
    Publication date: June 20, 2024
    Inventors: Bryan Edwards, Ulla Lashmar, Brian McGuinness, Mike Romanos, Thomas Sandal, Yumin Teng
  • Patent number: 11866510
    Abstract: The invention relates to chimeric antigen receptors (CAR) that comprise one or more single human variable domain antibody and cells that express such CAR. In particular, the invention relates to CARs that include multiple single human variable domain antibodies. In a particular embodiment, the one or more single human variable domain antibody binds to prostate membrane antigen.
    Type: Grant
    Filed: May 8, 2017
    Date of Patent: January 9, 2024
    Assignee: CRESCENDO BIOLOGICS LIMITED
    Inventors: Brian McGuinness, Colette Johnston
  • Publication number: 20230406954
    Abstract: The invention relates to binding molecules that bind specifically to prostate specific membrane antigen (PSMA), in particular, single human variable heavy chain domain antibodies and related methods for treatment of cancer.
    Type: Application
    Filed: June 28, 2023
    Publication date: December 21, 2023
    Inventors: Brian McGuinness, Isabelle Osuch, Chris Rossant, Mike Romanos, Nikki Royle, Thomas Sandal, Lorraine Thompson, Michele Writer
  • Patent number: 11746158
    Abstract: The invention relates to binding molecules that bind specifically to prostate specific membrane antigen (PSMA), in particular, single human variable heavy chain domain antibodies and related methods for treatment of cancer.
    Type: Grant
    Filed: October 22, 2021
    Date of Patent: September 5, 2023
    Assignee: Crescendo Biologics Limited
    Inventors: Brian McGuinness, Isabelle Osuch, Chris Rossant, Mike Romanos, Nikki Royle, Thomas Sandal, Lorraine Thompson, Michele Writer
  • Patent number: 11667705
    Abstract: Binding molecules to IL-17A. The binding molecules are useful in the treatment of disorders, for example psoriasis.
    Type: Grant
    Filed: April 8, 2020
    Date of Patent: June 6, 2023
    Assignee: Crescendo Biologics Limited
    Inventors: Bryan Edwards, Ulla Lashmar, Brian McGuinness, Mike Romanos, Thomas Sandal, Yumin Teng
  • Publication number: 20230133028
    Abstract: The invention relates to nucleic acid constructs for expression in mice for the reproduction of heavy chain only antibodies and VH domains, transgenic mice, related methods and uses.
    Type: Application
    Filed: October 19, 2022
    Publication date: May 4, 2023
    Applicant: Crescendo Biologics Limited
    Inventors: Yumin Teng, Joyce Young, Brian McGuinness, Mike Romanos, Marianne Brueggemann
  • Patent number: 11591398
    Abstract: The invention relates to PD-1 binding agents that block the interaction of PD-1 with its ligands, and the use of such binding agents in the treatment, prevention and detection of disease.
    Type: Grant
    Filed: January 8, 2018
    Date of Patent: February 28, 2023
    Assignee: CRESCENDO BIOLOGICS LIMITED
    Inventors: Phil Hayes, James Legg, Martyna Lewandowska, Colette Johnston, Brian McGuinness, Mike Romanos, Christine Rossant, Yumin Teng
  • Patent number: 11547099
    Abstract: The invention relates to nucleic acid constructs for expression in mice for the production of heavy chain only antibodies and VH domains, transgenic mice, related methods and uses.
    Type: Grant
    Filed: October 22, 2014
    Date of Patent: January 10, 2023
    Assignee: Crescendo Biologies Limited
    Inventors: Yumin Teng, Joyce Young, Brian McGuinness, Mike Romanos, Marianne Brueggemann
  • Publication number: 20220112305
    Abstract: The invention relates to binding molecules that bind specifically to prostate specific membrane antigen (PSMA), in particular, single human variable heavy chain domain antibodies and related methods for treatment of cancer.
    Type: Application
    Filed: October 22, 2021
    Publication date: April 14, 2022
    Inventors: Brian McGuinness, Isabelle Osuch, Chris Rossant, Mike Romanos, Nikki Royle, Thomas Sandal, Lorraine Thompson, Michele Writer
  • Patent number: 11236174
    Abstract: The invention relates to binding molecules that bind specifically to prostate specific membrane antigen (PSMA), in particular, single human variable heavy chain domain antibodies and related methods for treatment of cancer.
    Type: Grant
    Filed: January 12, 2017
    Date of Patent: February 1, 2022
    Assignee: CRESCENDO BIOLOGICS LIMITED
    Inventors: Brian McGuinness, Isabelle Osuch, Chris Rossant, Mike Romanos, Nikki Royle, Thomas Sandal, Lorraine Thompson, Michele Writer
  • Patent number: 10975161
    Abstract: The disclosure relates to binding molecules that bind specifically to prostate specific membrane antigen (PSMA), in particular, single human variable heavy chain domain antibodies and related methods for treatment of cancer.
    Type: Grant
    Filed: January 12, 2017
    Date of Patent: April 13, 2021
    Assignee: CRESCENDO BIOLOGICS LIMITED
    Inventors: Eleanora Balloi, Normann Goodwin, Brian McGuinness, Chris Rossant, Thomas Sandal, Lorraine Thompson
  • Publication number: 20200392244
    Abstract: The invention relates to binding molecules that bind specifically to prostate specific membrane antigen (PSMA), in particular, single human variable heavy chain domain antibodies and related methods for treatment of cancer.
    Type: Application
    Filed: January 12, 2017
    Publication date: December 17, 2020
    Inventors: Eleanora Balloi, Normann Goodwin, Brian McGuinness, Chris Rossant, Thomas Sandal, Lorraine Thompson, Michele Writer
  • Publication number: 20200347127
    Abstract: Binding molecules to IL-17A. The binding molecules are useful in the treatment of disorders, for example psoriasis.
    Type: Application
    Filed: April 8, 2020
    Publication date: November 5, 2020
    Inventors: Bryan Edwards, Ulla Lashmar, Brian McGuinness, Mike Romanos, Thomas Sandal, Yumin Teng
  • Publication number: 20200239573
    Abstract: The invention relates to PD-1 binding agents that block the interaction of PD-1 with its ligands, and the use of such binding agents in the treatment, prevention and detection of disease.
    Type: Application
    Filed: January 8, 2018
    Publication date: July 30, 2020
    Inventors: Phil Hayes, James Legg, Martyna Lewandowska, Colette Johnston, Brian McGuinness, Mike Romanos, Christine Rossant, Yumin Teng
  • Patent number: 10654924
    Abstract: Binding molecules to IL-17A. The binding molecules are useful in the treatment of disorders, for example psoriasis.
    Type: Grant
    Filed: January 12, 2016
    Date of Patent: May 19, 2020
    Assignee: CRESCENDO BIOLOGICS LIMITED
    Inventors: Bryan Edwards, Ulla Lashmar, Brian McGuinness, Mike Romanos, Thomas Sandal, Yumin Teng
  • Publication number: 20190144561
    Abstract: The invention relates to chimeric antigen receptors (CAR) that comprise one or more single human variable domain antibody and cells that express such CAR. In particular, the invention relates to CARs that include multiple single human variable domain antibodies. In a particular embodiment, the one or more single human variable domain antibody binds to prostate membrane antigen.
    Type: Application
    Filed: May 8, 2017
    Publication date: May 16, 2019
    Inventors: Brian McGuinness, Colette Johnston
  • Publication number: 20190023807
    Abstract: The disclosure relates to binding molecules that bind specifically to prostate specific membrane antigen (PSMA), in particular, single human variable heavy chain domain antibodies and related methods for treatment of cancer.
    Type: Application
    Filed: January 12, 2017
    Publication date: January 24, 2019
    Inventors: Eleanora Balloi, Normann Goodwin, Brian McGuinness, Chris Rossat, Thomas Sandal, Lorraine Thompson