Patents by Inventor Brian Milne

Brian Milne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and Therapies for Alleviating Pain
    Publication number: 20110053913
    Abstract: A method for alleviating or delaying onset of pain in a subject via administration of an ultra low dose of alpha-2 receptor antagonist which does not significantly block or inhibit alpha-2 receptor activity is provided. A non-selective alpha-2 receptor antagonist or a selective alpha-2A receptor antagonist may be administered.
    Type: Application
    Filed: June 25, 2010
    Publication date: March 3, 2011
    Inventors: Khem Jhamandas, Brian Milne, Catherine M. Cahill
  • Method and system for identifying and quantifying particles in flow systems
    Publication number: 20090209857
    Abstract: A method and system for quantifying particles in a flow system are provided.
    Type: Application
    Filed: November 6, 2008
    Publication date: August 20, 2009
    Inventors: Frank Secretain, Andrew Pollard, Christopher G. Ball, A.K. Mesbah Uddin, Mohamed Ali, Brian Milne, G. Andrew Y. Hamilton
  • Methods and Therapies for Potentiating a Therapeutic Action of an Alpha-2 Adrenergic Receptor Agonist and Inhibiting and/or Reversing Tolerance to Alpha-2 Adrenergic Receptor Agonists
    Publication number: 20080020076
    Abstract: Combination therapies of an alpha-2 adrenergic receptor agonist and an alpha-2 adrenergic receptor antagonist at a concentration effective to potentiate but not antagonize a therapeutic effect of the alpha-2 adrenergic receptor agonist are provided. Also provided are methods for use of these combination therapies in potentiating the therapeutic effects of alpha-2 adrenergic receptor agonists, inhibiting development of acute and/or chronic tolerance to alpha-2 adrenergic receptor agonists and treating conditions treatable by alpha-2 adrenergic receptor agonist therapy in a subject. In addition, a method for reversing alpha-2 adrenergic receptor agonist tolerance and/or restoring therapeutic effect of an alpha-2 adrenergic receptor agonist in a subject via administration of an alpha-2 adrenergic receptor antagonist at a concentration effective to potentiate, but not antagonize, the therapeutic effect of the alpha-2 adrenergic receptor agonist is provided.
    Type: Application
    Filed: July 20, 2007
    Publication date: January 24, 2008
    Inventors: Khem Jhamandas, Brian Milne
  • Methods and therapies for potentiating a therapeutic action of an opioid receptor agonist and inhibiting and/or reversing tolerance to opioid receptor agonists
    Publication number: 20070060501
    Abstract: Combination therapies of an opioid receptor agonist and an alpha-2 receptor antagonist in an amount effective to potentiate, but not antagonize, a therapeutic effect of the opioid receptor agonist are provided. Also provided are methods for use of these combination therapies in potentiating the therapeutic effects of opioid receptor agonists, inhibiting development of acute and/or chronic tolerance to opioid receptor agonists and treating conditions treatable by opioid receptor agonist therapy in a subject. In addition, a method for reversing opioid receptor agonist tolerance and/or restoring therapeutic effect of an opioid receptor agonist in a subject via administration of an alpha-2 receptor antagonist in an amount effective to potentiate, but not antagonize, the therapeutic effect of the opioid receptor agonist is provided.
    Type: Application
    Filed: August 30, 2006
    Publication date: March 15, 2007
    Inventors: Khem Jhamandas, Brian Milne