Abstract: Apparatus for illuminating the retina of an eye. The apparatus includes an illumination device and a lens system. The illumination device and the lens system combine to provide incident illumination from an apparent point source located within the lens system. The apparatus also includes an illumination transfer device. The illumination transfer device has two foci and the apparent point source of the lens system is provided at a first focus point of the illumination transfer device and an eye is accommodated at a second focus point of the illumination transfer device. The illumination transfer device transfers the incident illumination from the apparent point source into the eye to illuminate the retina.

Abstract: Apparatus for illuminating the retina of an eye. The apparatus includes an illumination device and a lens system. The illumination device and the lens system combine to provide incident illumination from an apparent point source located within the lens system. The apparatus also includes an illumination transfer device. The illumination transfer device has two foci and the apparent point source of the lens system is provided at a first focus point of the illumination transfer device and an eye is accommodated at a second focus point of the illumination transfer device. The illumination transfer device transfers the incident illumination from the apparent point source into the eye to illuminate the retina.

Abstract: Apparatus for illuminating the retina of an eye. The apparatus includes an illumination device and a lens system. The illumination device and the lens system combine to provide incident illumination from an apparent point source located within the lens system. The apparatus also includes an illumination transfer device. The illumination transfer device has two foci and the apparent point source of the lens system is provided at a first focus point of the illumination transfer device and an eye is accommodated at a second focus point of the illumination transfer device. The illumination transfer device transfers the incident illumination from the apparent point source into the eye to illuminate the retina.

Abstract: The present invention provides a rack for holding sample vials comprising: (i) a solid base; (ii) an upwardly extending wall around the perimeter of said base; (iii) a plurality of means for supporting a plurality of vials, each means for supporting one vial; and (iv) a means for draining liquid from said rack.

Abstract: Apparatus for illuminating the retina of an eye. The apparatus includes an illumination device and a lens system. The illumination device and the lens system combine to provide incident illumination from an apparent point source located within the lens system. The apparatus also includes an illumination transfer device. The illumination transfer device has two foci and the apparent point source of the lens system is provided at a first focus point of the illumination transfer device and an eye is accommodated at a second focus point of the illumination transfer device. The illumination transfer device transfers the incident illumination from the apparent point source into the eye to illuminate the retina.

Abstract: XBRL data may be automatically mapped back and forth between an XBRL instance an set of automatically generated flat tables, where each table represents the projection of a single hypercube.

Abstract: The present invention provides a rack for holding sample vials comprising: (i) a solid base; (ii) an upwardly extending wall around the perimeter of said base; (iii) a plurality of means for supporting a plurality of vials, each means for supporting one vial; and (iv) a means for draining liquid from said rack.

Abstract: XBRL data may be automatically mapped back and forth between an XBRL instance an set of automatically generated flat tables, where each table represents the projection of a single hypercube.

Abstract: XBRL data may be automatically mapped back and forth between an XBRL instance an set of automatically generated flat tables, where each table represents the projection of a single hypercube.

Abstract: Apparatus for illuminating the retina of an eye. The apparatus comprising an illumination device, a lens system, wherein the illumination device and the lens system combine to provide incident illumination from an apparent point source located within the lens system. The apparatus further comprising an illumination transfer device, wherein the illumination transfer device has two foci and the apparent point source of the lens system is provided at a first focus point of the illumination transfer device and an eye is accommodated at a second focus point of the illumination transfer device, and wherein the illumination transfer device transfers the incident illumination from the apparent point source into the eye to illuminate the retina.

Abstract: XBRL instance data configured according to a given XBRL hypercube specification (or an extension thereof) may be automatically mapped to a multidimensional database configured according to the given XBRL hypercube specification. Such a multidimensional database may be configured for analytical processing of multi-dimensional analytical queries related to the XBRL instance data and/or for analytical processing by a business intelligence tool. Multidimensional data from a multidimensional database may also be automatically mapped to an automatically-generated XBRL hypercube specification structured according to the multidimensional database.

Abstract: Relationships between XBRL hypercubes, including implicit relationships, may be automatically determined based on shared dimensions. Once such relationships are understood, “generic” software (software that is not specific to a particular taxonomy) may be built to provide some or all of the following functionalities: determine, enforce, and/or encourage referential integrity; deduce (graph) ordered relationships between hypercubes; make inferences about those relationships; “join” or “split” hypercubes; create isomorphic and/or homomorphic views of a hypercube for user presentation; and/or assemble and order primary items (attached to hypercubes) in a logical (graph) order.

Abstract: XBRL data may be automatically mapped back and forth between an XBRL instance an set of automatically generated flat tables, where each table represents the projection of a single hypercube.

Abstract: XBRL instance data configured according to a given XBRL hypercube specification (or an extension thereof) may be automatically mapped to a multidimensional database configured according to the given XBRL hypercube specification. Such a multidimensional database may be configured for analytical processing of multi-dimensional analytical queries related to the XBRL instance data and/or for analytical processing by a business intelligence tool. Multidimensional data from a multidimensional database may also be automatically mapped to an automatically-generated XBRL hypercube specification structured according to the multidimensional database.

Abstract: Relationships between XBRL hypercubes, including implicit relationships, may be automatically determined based on shared dimensions. Once such relationships are understood, “generic” software (software that is not specific to a particular taxonomy) may be built to provide some or all of the following functionalities: determine, enforce, and/or encourage referential integrity; deduce (graph) ordered relationships between hypercubes; make inferences about those relationships; “join” or “split” hypercubes; create isomorphic and/or homomorphic views of a hypercube for user presentation; and/or assemble and order primary items (attached to hypercubes) in a logical (graph) order.

Abstract: A method for alleviating or delaying onset of pain in a subject via administration of an ultra low dose of alpha-2 receptor antagonist which does not significantly block or inhibit alpha-2 receptor activity is provided. A non-selective alpha-2 receptor antagonist or a selective alpha-2A receptor antagonist may be administered.

Abstract: A method and system for quantifying particles in a flow system are provided.

Abstract: Combination therapies of an alpha-2 adrenergic receptor agonist and an alpha-2 adrenergic receptor antagonist at a concentration effective to potentiate but not antagonize a therapeutic effect of the alpha-2 adrenergic receptor agonist are provided. Also provided are methods for use of these combination therapies in potentiating the therapeutic effects of alpha-2 adrenergic receptor agonists, inhibiting development of acute and/or chronic tolerance to alpha-2 adrenergic receptor agonists and treating conditions treatable by alpha-2 adrenergic receptor agonist therapy in a subject. In addition, a method for reversing alpha-2 adrenergic receptor agonist tolerance and/or restoring therapeutic effect of an alpha-2 adrenergic receptor agonist in a subject via administration of an alpha-2 adrenergic receptor antagonist at a concentration effective to potentiate, but not antagonize, the therapeutic effect of the alpha-2 adrenergic receptor agonist is provided.

Abstract: Embodiments of the present invention include information services, methods and systems to facilitate gathering and management of information by home users and professional users of information gathering, processing, and distribution services, and user interfaces through which users communicate with information services. In one embodiment of the present invention, a central information gathering, processing, and distribution service provides a simple, but robust and highly functional, interface to remote home users and professional users to allow the home users and professional users to continuously receive updated information gleaned from continuous searching of the Internet and other information sources by the information service. The interface allows users to define, refine, and stably store interests that define information searches continuously carried out, on behalf of the user, by the information gathering, processing, and distribution service.

Abstract: Combination therapies of an opioid receptor agonist and an alpha-2 receptor antagonist in an amount effective to potentiate, but not antagonize, a therapeutic effect of the opioid receptor agonist are provided. Also provided are methods for use of these combination therapies in potentiating the therapeutic effects of opioid receptor agonists, inhibiting development of acute and/or chronic tolerance to opioid receptor agonists and treating conditions treatable by opioid receptor agonist therapy in a subject. In addition, a method for reversing opioid receptor agonist tolerance and/or restoring therapeutic effect of an opioid receptor agonist in a subject via administration of an alpha-2 receptor antagonist in an amount effective to potentiate, but not antagonize, the therapeutic effect of the opioid receptor agonist is provided.