Abstract: The disclosure provides methods of inhibiting human aldosterone synthase, treating hypertension, or treating primary aldosteronism in a subject in need thereof, comprising administering an effective amount of (R)-Compound 1 to the subject, wherein (R)-Compound 1 is: Formula (I).

Abstract: A coiled filter for use in a hydraulic braking system of a vehicle comprises a coiled mesh-like structure which is configured to be installed around a first surface of a cylindrical hydraulic component. The coiled filter is configured to have an internal spring force as a retention force which couples the filter to the first surface of the cylindrical hydraulic component. The filter may be pre-coiled prior to installation by plastically deforming to a diameter that is smaller than the diameter of the cylindrical hydraulic component on which the filter is installed.

Abstract: A root portion of a root-analog dental implant may include a core positioned in an approximate center of the root portion of the dental implant. The core may provide mechanical strength and/or support for the dental implant and may include one or more struts. The root-analog dental implant may further include a porous surface positioned on a portion of a vertically oriented exterior surface of the core. The struts may be configured and arranged to provide mechanical strength and/or support for the root-analog dental implant.

Abstract: Control zone devices that integrate a valve, filter, and pressure regulator within a single device are provided. Specifically, the control zone devices include a main body having a base portion with an inlet passage and an outlet passage attachable to a conduit and a body portion extending from the base portion having an interior for receiving a filter. The control zone devices further include a valve body including a solenoid bowl for attaching a solenoid and an interface cap for removably coupling the valve body to the main body of the control zone device and forming an interface between the valve body and the main body to operate the valve. The control zone devices also include a pressure regulator. In some configurations, the pressure regulator is positioned in a vent flow path of the valve body downstream of the solenoid for regulating pressure at the valve.

Abstract: A system or method for determining a battery state can include generating a set of models based on a measured response of a plurality of batteries to an applied load, measuring battery properties of a battery, and using a state estimator to determine a battery state associated with a battery.

Abstract: A head-wearable sensor arrangement for obtaining a measurement of biosignal of a user is provided. The present disclosure also relates to a stimulus-providing wireless mobile device and a computing system. The head-wearable sensor arrangement may send time-stamped medical data comprising a representation of the measurement to the wireless mobile device time-synchronized with the arrangement. The wireless mobile device may send the time-stamped medical data to a computing system. The computing system may process the time-stamped medical data to determine an indicator of health, well-being or performance of the user. The processing may involve decomposing the measurement and using residuals of an autoregressive model or a robust aggregation method on the decomposed measurement.

Abstract: A portable ultrasound system, such as a handheld ultrasound device or a flexible patch, includes an ultrasound transducer in direct contact with a portion of facial skin. The ultrasound transducer generates surface acoustic waves (SAW) across the portion of facial skin to improve properties of the skin and/or enhance absorption of a facial skin care product by enabling an active ingredient of the facial skin care product to penetrate the stratum corneum layer and be delivered to sub-dermal tissues of the skin.

Abstract: A field-assembled satellite communications terminal has a plurality of discrete, modular aperture blocks. Each aperture block contains an electrically steered antenna aperture, and a plurality of interconnection ports for power and data communications between the plurality of aperture blocks. The plurality of interconnection ports are removably connectable by the end user in the field. The terminal further has a signal processing system for receiving, processing, and generating signals to and from the apertures. The aperture blocks are connected to each other in the field and self-configure to form an electrically-steered antenna.

Abstract: A perspiration sensing system includes a sensor patch and a smart device. The sensor patch includes one or more perspiration sensing portions. The one or more perspiration sensing portions include an inlet having a predefined size to receive perspiration from a predefined number of sweat glands and an outlet for reducing back pressure. At least one perspiration sensing portion includes a channel having a colorimetric sensing material that changes color when exposed to perspiration. At least one perspiration sensing portion includes a colorimetric assay in a substrate that changes color when exposed to biochemical components of perspiration. The system further includes a smart device having a camera that can take a picture of the sensor patch and determine the volume, rate of perspiration, and/or biochemical components of the perspiration from the one or more perspiration sensing portions.

Abstract: A circuit has at least one amplifier and a signal routing device such as one or more switches, and an array of antenna elements from which some subset must be enabled and processed at a time. The antenna elements can be grouped in accordance with an organization scheme (e.g., rows, columns) to enable more flexibility in selecting and routing the signals. The system is used to create one or more beams, which can be pointed (steered) to a wide range of directions by means of selecting one or more feed antennas in a switched-feed antenna without including full receive and transmit circuitry (DSP, frequency conversion) for each feed in the array. In this case, minimizing the number of DSP chains is desirable to reduce the cost, power, and complexity of the antenna. The resulting beam(s) can be combined and manipulated to support multiple users, track several targets, increase operational range, increase radar resolution, or data-rate in communications.

Abstract: Embodiments disclosed herein are directed to fluid collection assemblies including one or more leak prevention features, systems including the same, and methods of using the same are disclosed herein. An example fluid collection assembly includes a fluid impermeable barrier at least defining a chamber, at least one opening, and a fluid outlet. The fluid collection assembly also include at least one porous material disposed in the chamber and one or more leak prevention features. The leak prevention features may include at least one of a shape of the fluid collection assembly that improves fit between the fluid collection assembly and a patient, at least one absorbent material at least partially disposed outside of the chamber, a base configured to have a patient disposed thereon, or one or more features that allows a length of the fluid collection assembly to change.

Abstract: A circuit has at least one amplifier and a signal routing device such as one or more switches, and an array of antenna elements from which some subset must be enabled and processed at a time. The antenna elements can be grouped in accordance with an organization scheme (e.g., rows, columns) to enable more flexibility in selecting and routing the signals. The system is used to create one or more beams, which can be pointed (steered) to a wide range of directions by means of selecting one or more feed antennas in a switched-feed antenna without including full receive and transmit circuitry (DSP, frequency conversion) for each feed in the array. In this case, minimizing the number of DSP chains is desirable to reduce the cost, power, and complexity of the antenna. The resulting beam(s) can be combined and manipulated to support multiple users, track several targets, increase operational range, increase radar resolution, or data-rate in communications.

Abstract: A system, device and methods for inhibiting biofilm formation and preventing infection associated with indwelling medical devices by generating and applying surface acoustic waves (SAW) to a surface of the indwelling medical device. One or more piezoelectric ultrasound transducer(s) in direct contact with a surface of the implantable medical device generates high frequency mechanical vibrations in a range from KHz to MHz upon receipt of an electrical signal from a processor. The high frequency mechanical vibrations produce SAW in the nanometer range along a surface of the indwelling medical device and inhibit formation of bacterial biofilms.

Abstract: A casted thermostatic housing for an engine coolant system. The housing has a plurality of exterior heat dissipating projections. An interior post for contacting a thermostatic element is circular and preferably tapered. The housing is casted metal and is preferably aluminum.

Abstract: Apparatuses and techniques are presented for detecting bit line open circuits and short circuits in a memory device in which a memory die is inverted and bonded to a control die. In one approach, the control die comprises a set of bit lines which are connected to a set of bit lines of the memory die, and the set of bit lines of the control die comprise ground transistors, e.g., transistors connected to a ground node. Ground transistors of even-numbered bit lines may be commonly controlled, while ground transistors of odd-numbered bit lines are commonly controlled. The ground transistors may be controlled to detect open circuits and short circuits in the bit lines of the control die and the memory die. A laser scanning technique can also be used to determine a physical location of a defect of a bit line.

Abstract: Embodiments disclosed herein are fluid collection assemblies including one or more securement elements and methods for collecting fluids with the fluid collection assemblies. In an embodiment, a fluid collection assembly includes a fluid collection device and means for securing the fluid collection device to the user with a fluid permeable body of the fluid collection device positioned proximate to the urethra of the user through the opening in a fluid impermeable barrier of the fluid collection device.

Abstract: A training device useful at least for exercises for bicep workouts and strengthening is configurable for multiple types of movement and use. The training device has a frame, two arm cradles attached in variable configurations, and a multi-use strap. The arm cradles are removable from the frame for re-configuration or for storage and transport. To configure the training device for compact storage and transportation, the arm cradles can be detached, nestled into the inner side of the frame, and wrapped by the strap. To attain various workout configurations, the arm cradles can be interchanged on the frame, reoriented on the frame, and adjusted to preferred lateral positions on the frame.

Abstract: A method of operating a satellite communications terminal.

Abstract: An improved injection needle assembly configured to inhibit formation of bacterial biofilm near the injection needle surface following insertion into the body. The injection needle assembly includes an elongated injection tube having a pointed tip at a distal end for insertion into tissue and a base portion at a proximal end, the base portion comprising an attachment portion for an injector of liquid through the injection needle; and an actuator comprising a piezoelectric material coupled to the base portion of the injection needle, the actuator being configured to receive an electrical signal to initiate generation of surface acoustic waves (SAW) along a longitudinal axis of the injection needle.