Patents by Inventor Brian P. Dwyer

Brian P. Dwyer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230165947
    Abstract: The present application relates to antibodies that bind to small molecules such as cyclophosphamide, ifosfamide, and analogs thereof, and immunological assays for determining the presence and/or quantifying the amount of cyclophosphamide and/or ifosfamide in a sample. By way of example, such immunological assays can be used for environmental testing.
    Type: Application
    Filed: August 9, 2022
    Publication date: June 1, 2023
    Inventor: Brian P. Dwyer
  • Patent number: 11413342
    Abstract: The present application relates to antibodies that bind to small molecules such as cyclophosphamide, ifosfamide, and analogs thereof, and immunological assays for determining the presence and/or quantifying the amount of cyclophosphamide and/or ifosfamide in a sample. By way of example, such immunological assays can be used for environmental testing.
    Type: Grant
    Filed: September 27, 2019
    Date of Patent: August 16, 2022
    Assignee: Becton, Dickinson and Company
    Inventor: Brian P. Dwyer
  • Patent number: 10584926
    Abstract: A heat exchanger that includes a membrane of graphene oxide is disclosed, as is a heat exchange system employing such a heat exchanger. The heat exchanger permits the use of water from non-traditional sources, such as waste water, brackish and sea water, in a cooling loop. Clean water and sensible heat permeate through the membrane, simultaneously cooling and purifying water in the cooling loop.
    Type: Grant
    Filed: December 19, 2013
    Date of Patent: March 10, 2020
    Assignees: National Technology & Engineering Solutions of Sandia, LLC
    Inventors: Brian P. Dwyer, Charles P. Morrow, Phillip I. Pohl, Laura Biedermann, Paul Crozier, Kevin R. Zavadil, Frederick J. Glasscott
  • Publication number: 20200016252
    Abstract: The present application relates to antibodies that bind to small molecules such as cyclophosphamide, ifosfamide, and analogs thereof, and immunological assays for determining the presence and/or quantifying the amount of cyclophosphamide and/or ifosfamide in a sample. By way of example, such immunological assays can be used for environmental testing.
    Type: Application
    Filed: September 27, 2019
    Publication date: January 16, 2020
    Inventor: Brian P. Dwyer
  • Patent number: 10434160
    Abstract: The present application relates to antibodies that bind to small molecules such as cyclophosphamide, ifosfamide, and analogs thereof, and immunological assays for determining the presence and/or quantifying the amount of cyclophosphamide and/or ifosfamide in a sample. By way of example, such immunological assays can be used for environmental testing.
    Type: Grant
    Filed: September 7, 2016
    Date of Patent: October 8, 2019
    Assignee: Becton, Dickinson and Company
    Inventor: Brian P. Dwyer
  • Publication number: 20180326031
    Abstract: The present application relates to antibodies that bind to small molecules such as cyclophosphamide, ifosfamide, and analogs thereof, and immunological assays for determining the presence and/or quantifying the amount of cyclophosphamide and/or ifosfamide in a sample. By way of example, such immunological assays can be used for environmental testing.
    Type: Application
    Filed: September 7, 2016
    Publication date: November 15, 2018
    Inventor: Brian P. Dwyer
  • Patent number: 7514004
    Abstract: A low-cost, water treatment system and method for reducing arsenic contamination in small community water storage tanks. Arsenic is removed by using a submersible pump, sitting at the bottom of the tank, which continuously recirculates (at a low flow rate) arsenic-contaminated water through an attached and enclosed filter bed containing arsenic-sorbing media. The pump and treatment column can be either placed inside the tank (In-Tank) by manually-lowering through an access hole, or attached to the outside of the tank (Out-of-Tank), for easy replacement of the sorption media.
    Type: Grant
    Filed: May 1, 2008
    Date of Patent: April 7, 2009
    Assignee: Sandia Corporation
    Inventors: Patrick V. Brady, Brian P. Dwyer, James L. Krumhansl, Joseph D. Chwirka
  • Patent number: 6834720
    Abstract: An improved method and apparatus for injecting particulate media into the ground for constructing underground permeable reactive barriers, which are used for environmental remediation of subsurface contaminated soil and water. A media injector sub-assembly attached to a triple wall drill string pipe sprays a mixture of active particulate media suspended in a carrier fluid radially outwards from the sub-assembly, at the same time that a mixing fluid is sprayed radially outwards. The media spray intersects the mixing spray at a relatively close distance from the point of injection, which entrains the particulate media into the mixing spray and ensures a uniform and deep dispersion of the active media in the surrounding soil. The media injector sub-assembly can optionally include channels for supplying compressed air to an attached down-the-hole hammer drive assembly for use during drilling.
    Type: Grant
    Filed: December 3, 2002
    Date of Patent: December 28, 2004
    Assignee: Sandia Corporation
    Inventors: Brian P. Dwyer, Stephen F. Dwyer, Francine S. Vigil, Willis E. Stewart
  • Publication number: 20020123068
    Abstract: The present invention provides non-radioactively labeled synthetic substrates for enzymatic reactions which exhibit markedly improved solubility having the general structure *F-R1-L1-R2-PHc1-PS-PHc2-(R3-L-R4-T)y. These substrates may be designed to carry a charge to allow electrophoretic separation of substrates and reaction products. The invention also provides enzymatic activity assays for protein kinases, phosphatases and proteases utilizing the substrates of the invention, as well as methods of producing these substrates. In addition, the invention also provides libraries of the substrates, and methods of utilizing these libraries to select optimal synthetic peptide enzyme substrates for high-throughput screening assays.
    Type: Application
    Filed: January 31, 2001
    Publication date: September 5, 2002
    Inventors: Brian P. Dwyer, John R. Havens
  • Patent number: 6357968
    Abstract: A method and apparatus for constructing a underground barrier wall structure using a jet grout injector subassembly comprising a pair of primary nozzles and a plurality of secondary nozzles, the secondary nozzles having a smaller diameter than the primary nozzles, for injecting grout in directions other than the primary direction, which creates a barrier wall panel having a substantially uniform wall thickess. This invention addresses the problem of the weak “bow-tie” shape that is formed during conventional jet injection when using only a pair of primary nozzles. The improvement is accomplished by using at least four secondary nozzles, of smaller diameter, located on both sides of the primary nozzles. These additional secondary nozzles spray grout or permeable reactive materials in other directions optimized to fill in the thin regions of the bow-tie shape. The result is a panel with increased strength and substantially uniform wall thickness.
    Type: Grant
    Filed: January 12, 2000
    Date of Patent: March 19, 2002
    Assignee: Sandia Corporation
    Inventors: Brian P. Dwyer, Willis E. Stewart, Stephen F. Dwyer
  • Patent number: 5986083
    Abstract: Oligomers having phosphonate internucleosidyl linkages mixed with non-phosphonate internucleosidyl linkages which hybridize to RNA target sequences and methods for their preparation are provided.
    Type: Grant
    Filed: November 17, 1994
    Date of Patent: November 16, 1999
    Assignee: Genta, Inc.
    Inventors: Brian P. Dwyer, Lyle John Arnold, Jr., Mark Alan Reynolds
  • Patent number: D655424
    Type: Grant
    Filed: November 18, 2009
    Date of Patent: March 6, 2012
    Assignee: Becton, Dickinson and Company
    Inventors: Scott E. Castanon, Martin J. Bouliane, Richard R. Anderson, John J. Carrino, Brian P. Dwyer, Gregory K. Bond, Bryan Towns, Jorge Haro