Patents by Inventor Brian P. Lispky

Brian P. Lispky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cytoplasmic modulators of integrin regulation/signaling
    Publication number: 20030044958
    Abstract: The present invention provides purified and isolated polynucleotides encoding IRP polypeptides which regulate &bgr;2 and &bgr;7 integrins and which are contemplated to participate in integrin signaling and/or recycling pathways. Also provided are methods for identifying modulators of IRP activities and methods for identifying other proteins which interact with IRP polypeptides in signaling pathways. Modulators of IRP interactions are contemplated to be useful, for example, in monitoring and treating inflammatory processes involving leukocytes.
    Type: Application
    Filed: March 26, 2001
    Publication date: March 6, 2003
    Applicant: ICOS Corporation
    Inventors: Donald E. Staunton, Brian P. Lispky
  • Method to identify proteins which bind to integrin regulatory proteins
    Patent number: 6210914
    Abstract: The present invention provides purified and isolated polynucleotides encoding IRP (Integrin Regulatory Protein) polypeptides which regulate &bgr;2 and &bgr;7 integrins and which are contemplated to participate in integrin signaling and/or recycling pathways. Also provided are methods for identifying modulators of IRP activities and methods for identifying other proteins which interact with IRP polypeptides in signaling pathways. Modulators of IRP interactions are contemplated to be useful, for example, in monitoring and treating inflammatory processes involving leukocytes.
    Type: Grant
    Filed: February 13, 1998
    Date of Patent: April 3, 2001
    Assignee: ICOS Corporation
    Inventors: Donald E. Staunton, Brian P. Lispky
  • Cytoplasmic modulators of integrin regulation/signaling
    Patent number: 5958705
    Abstract: The present invention provides purified and isolated polynucleotides encoding IRP (integrin regulatory protein) polypeptides which regulate .beta..sub.2 and .beta..sub.7 integrins and which are contemplated to participate in integrin signaling and/or recycling pathways. Also provided are methods for identifying modulators of IRP activities and methods for identifying other proteins which interact with IRP polypeptides in signaling pathways. Modulators of IRP interactions are contemplated to be useful, for example, in monitoring and treating inflammatory processes involving leukocytes.
    Type: Grant
    Filed: April 15, 1997
    Date of Patent: September 28, 1999
    Assignee: ICOS Corporation
    Inventors: Donald E. Staunton, Brian P. Lispky