Abstract: The present disclosure relates to kits, compositions, or one or more methods of detecting an analyte-of-interest using one or more protein-oligonucleotide reporters of the present disclosure. For example, the present disclosure relates to a composition, including: a conjugate reaction product of: a signal emitting peptide or functional fragment thereof having a predetermined electrophilic residue; a linker characterized as a fused sterol or stanol ring system, having a nucleophilic group at a 3-position of an A-ring of a fused sterol or stanol ring system with beta or alpha stereochemistry; and an oligonucleotide having a 5? end and a 3? end, wherein the composition is characterized by one of 3? end or 5? end attached to the linker and one of 3? end or 5? end attached to a quencher, and wherein the linker is covalently linked to the predetermined electrophilic residue.

Abstract: A vehicle powered step-up charging device (SUCD). The SUCD can be in a terminal version which plugs in at the terminal end of a vehicle supplied power supply, such as a 7-pin RV socket. Alternatively, the SUCD is an in-line version where it is situated between the vehicle's powerplant and a RV socket. In another alternative, the SUCD is a bottle SUCD version having a form for seating within a bottle holder of a bicycle. In this case, an input line couples to a 12V output on the vehicle. Circuitry inside the bottle SUCD steps up voltage which is then output via an output line for charging one or more devices such as an electric bike during transit on a bike rack. This disclosure includes configurations for delivering the stepped up voltage at an RV socket as well as methods for using terminal, in-line, or bottle SUCDs.

Abstract: A well system and a related method are discussed. The well system, in one aspect, includes a wellbore extending through a subterranean hydrocarbon producing zone, as well as production tubing located in the wellbore, the production tubing including a first inflow control valve configured to regulate a first inflow of hydrocarbons from the subterranean hydrocarbon producing zone into the production tubing. The well system, in accordance with this aspect, further includes a flange coupled to the production tubing and having a fitting positioned proximate a downhole end thereof, and a fiber optic cable installed within the wellbore, an end connector of the fiber optic cable coupled end to end with the fitting of the flange to fix the fiber optic cable relative to the first inflow control valve.

Abstract: Provided are a system and methodology for fraud detection and prevention to minimize an ongoing effect of fraud attack. The minimization is rooted in leveraging real-time recognition for delineated, time-based frequency for patterning within transaction data in which such patterning can be indicative of fraud. Once the recognition is performed, affected entities can be notified such that they may then institute efforts to thwart effects of the fraud attack. Still further, the recognition can serve to mitigate effects of fraud attack for subsequent iterations of transaction data by automating, in real-time, disapproval of transactions infected with the aforementioned patterning.

Abstract: A cap covers an open end of a drain pan fitting of an appliance drain pan. The cap comprises a cylindrical body and a non-planar water-soluble membrane. The cylindrical body has a first end with a first end opening, a second end with a second end opening, and a longitudinal through-hole extending between the first end opening and the second end opening. The non-planar water-soluble membrane is positioned to at least partially obstruct the through-hole when the membrane is intact such that air flow through the through-hole is inhibited in the absence of water in the drain pan. The membrane is adapted to dissolve when exposed to water in the drain pan such that water in the drain pan is not inhibited from exiting the drain pan through the through-hole.

Abstract: A receptacle connector includes a receptacle housing having a housing mounting end configured to be mounted to a host circuit board and a slot at a housing mating end configured to receive a mating end of a pluggable module. The receptacle housing includes contact pockets that receive interposer contacts. The receptacle connector includes a flexible circuit having circuit conductors extending between a mating end and a terminating end configured to be terminated to the host circuit board. Each interposer contact includes an inner mating interface forming a separable interface configured to be mated with module contacts of the pluggable module and an outer mating interface connected to the mating end of the corresponding circuit conductor.

Abstract: Multi-purpose and single function tools for splitting wood, material handling, and a variety of other uses are disclosed for projects around home, at a campground, or at a construction site. The tools are anchored entirely by the hitch receiver of a vehicle, the frame of a trailer, or by various forms of jack stands. The vehicle and jack stand supported wood splitters comprise a blade portion and a fixation portion extending from the blade portion. The blade portion comprises a generally upward facing cut edge. In some forms, the splitter is in the form of a jack stand which can be converted for use as a multi-purpose tool for material handling and other useful functions. Methods of use of the tools are disclosed as well as methods of converting the tool from one mode to another.

Abstract: A stabilizer for use with a delivery system is provided. The stabilizer receives a delivery system, such as a handle portion, and prevents unwanted movement of the delivery system during a medical procedure. The stabilizer desirably includes an elongate rail that is adapted to be secured to a base or table. A rail dock is adapted to releasably couple to the delivery system. The rail dock is slidably mounted along an upper surface of the rail and includes a brake assembly. The brake assembly preferably includes a toggle member with at least one push button, wherein actuation of the push button may release or lock the brake assembly. Components of the stabilizer are provided for allowing the stabilizer to be used with different delivery systems and the stabilizer is capable of being secured to different sized tables.

Abstract: A back plate configured to support a circuit board includes a body. The body defines a central recess formed into a top surface thereof, and a raised main support column extending from the central recess and adapted to support the circuit board.

Abstract: An anchor driver is transluminally advanceable to a heart of a subject, and comprises (a) a shaft; (b) a head, coupled to the shaft at a distal part of the anchor driver, and configured to engage a tissue anchor; and (c) a stiffening element that, while the head remains engaged with the tissue anchor, is repositionable from outside of the subject in a manner that transitions the anchor driver between (i) a first state, and (ii) a second state in which the distal part of the anchor driver is stiffer than in the first state. Other embodiments are also disclosed.

Abstract: Vascular access devices and methods of their use are provided. In one embodiment, a vascular access device includes a catheter and at least one deployable wire. The catheter includes a primary lumen extending from a proximal end to a distal end of the catheter. The at least one deployable wire is secured to the catheter and configured to move relative to the catheter between a delivery configuration and a deployed configuration.

Abstract: A busbar assembly includes a first busbar having a mating interface for mating with an electrical component to power the electrical component and a second busbar having a mating interface for mating with the electrical component to power the electrical component. The busbar assembly includes a first thermal conduit extending along the first busbar that allows liquid coolant to flow therethrough to dissipate heat from the first busbar. The busbar assembly includes a second thermal conduit extending along the second busbar that allows liquid coolant to flow therethrough to dissipate heat from the second busbar.

Abstract: A detergent product containing a detergent composition is provided.

Abstract: An articulating tire valve install-removal tool and related methods for use. The articulating tire valve install-removal tool has a body comprising an outer perimeter, an inner recess, a threaded member, a linkage and a contact member. The articulating tire valve install-removal tool components are connected to each other and secured within the body so one or more components can rotate around one or more axes. Together these components facilitate in the valve being installed and removed perpendicular or generally perpendicular to the valve hole on the wheel. The articulating tire valve stem tool includes a linkage assembly that is attached to the body to facilitate in ensuring the valve is installed and removed with the valve perpendicular to the valve hole in the wheel rim.

Abstract: An implant includes a tether and a series of anchors. Each anchor includes (i) a tissue-engaging element, (ii) a head that is slidably coupled to the tether and that includes a lock that is biased to lock in a manner that locks the head to the tether, and (iii) a push-button operatively coupled to the lock. A delivery tool includes a flexible tube that is transluminally advanceable to the heart, and a driver. The driver is configured to, for each of the anchors sequentially, (i) advance the anchor through the flexible tube to the heart while the lock is maintained unlocked by the flexible tube constraining the push-button, (ii) anchor the anchor to tissue of the heart, and (iii) release the push-button by deploying the head out of the flexible tube, the lock responsively locking. Other embodiments are also described.

Abstract: A textile formulation adapted to impart an odor-controlling property to a textile material. The textile formulation is an odor capturing formulation comprising a carrier and an odor capturing agent. The odor capturing agent is a liquid dispersible boehmite. An odor absorbing article and a method of treating the odor absorbing article is also provided.

Abstract: A sewer cleanout cap characterized by reliable and rapid location underground thereby eliminating time wasted attempting to locate, dig for, repair, or replace standard cleanout caps. The cleanout cap comprises a generally disc shaped threaded cap body having a distal face and a central axis with a drive block extending proximally from a proximal face of the cap body. A first recess can extend into the cap body from the distal face, and a second recess can extend from the distal face into the drive block. A first magnet is generally aligned with the first axis and is fixed and sometimes sealed within the sewer cleanout cap. First magnet fixation approaches include securing the first magnet in a non-corrosive housing, molding the magnet into the cap, securing within in a first recess using friction or adhesives, securing it to a post, or securing the first magnet within deflectable prongs.

Abstract: A translatable carriage exercise machine comprising elongate side rails. A moveable carriage is translatable along the side rails. An upper support surface on the carriage is useable to at least partially support a user. A plurality of elastic tension members can be secured to a bottom of the moveable carriage and are fixable to a plurality of spring anchors near an end of the machine. A pair of handles under elastic tension are directed toward an end of the machine. An upright footbar can be positioned at an end of the machine. A rotational resistance mechanism is integrated in the machine comprising an elongate resistance band having an extended configuration and a retracted configuration. The rotational resistance mechanism comprises a resistor comprising a load member. A user can option to utilize one or more of the elastic tension members and/or rotational resistance mechanism during exercise on the machine.