Abstract: A single use syringe and a plunger rod assembly for such a syringe are provided. The syringe includes features that cause the plunger rod to be locked with respect to the syringe barrel upon completion of an injection stroke. The locking device may include barbs for engaging the syringe barrel and relatively long, proximally extending legs. The legs include barbs for engaging the syringe barrel and end portions for engaging the plunger rod. The plunger rod assembly includes a recess defined by converging surfaces, the recess being displaced from the longitudinal axis thereof. A locking element that fits a smaller syringe can thereby be used in a larger syringe as well.

Abstract: A single use syringe is provided. The syringe includes features that cause the plunger rod to be locked with respect to the syringe barrel upon completion of a two stroke injection procedure, such as a drug reconstitution and injection sequence. The locking device may include barbs for engaging the syringe barrel and relatively long, proximally extending legs. The legs include barbs for engaging the syringe barrel and end portions for engaging the plunger rod. The plunger rod includes a recess defined by converging surfaces, the recess being displaced from the longitudinal axis thereof. The surfaces of the plunger rod define teeth that are engageable with the locking element.

Abstract: A reconstitution syringe assembly comprises an elongate cannula made of thermoplastic material having an outside diameter of at least 2 mm, a distal tip capable of piercing an elastomeric vial stopper and a proximal end having discontinuities on its exterior surface. A barrel made of thermoplastic material includes a tip which is molded in intimate contact around the proximal end of the cannula engaging the discontinuities to provide a permanently attached cannula. The cannula extends at least 23 mm from the distal wall of the barrel. An integrally formed one-piece thermoplastic plunger and stopper is provided.

Abstract: An operable single-use syringe includes a barrel having an inside surface defining a chamber for retaining fluid and an open proximal end. A plunger rod having an elongate body portion and a stopper at its distal end slidably positioned in fluid-tight engagement in the barrel. A locking element is positioned in the barrel between the plunger rod and the inside surface of the barrel. The locking element has a base and two leg members projecting therefrom that are positioned in longitudinal grooves in the plunger rod. The locking element only moves distally in the barrel and prevents re-use of the syringe after its contents have been discharged.

Abstract: A single use syringe and a plunger rod assembly for such a syringe are provided. The syringe includes features that cause the plunger rod to be locked with respect to the syringe barrel upon completion of an injection stroke. The locking device may include barbs for engaging the syringe barrel and relatively long, proximally extending legs. The legs include barbs for engaging the syringe barrel and end portions for engaging the plunger rod. The plunger rod assembly includes a recess defined by converging surfaces, the recess being displaced from the longitudinal axis thereof. A locking element that fits a smaller syringe can thereby be used in a larger syringe as well.