Patents by Inventor Brian Pierce

Brian Pierce has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200201319
    Abstract: Micro-authorization of remote assistance for an autonomous vehicle is described herein. A constraint that inhibits propulsion by a mechanical system of the autonomous vehicle is activated by a computing system of the autonomous vehicle, wherein a signal that identifies the activated constraint is transmitted from the autonomous vehicle to a remote computing system. The remote computing system generates instructions to deactivate the activated constraint. A return signal is transmitted from the remote computing system that specifies instructions to deactivate the constraint and a distance to desirably advance the autonomous vehicle. The computing system of the autonomous vehicle deactivates the constraint and the mechanical system is controlled to advance the autonomous vehicle when signal latency is less than a predetermined threshold duration of time.
    Type: Application
    Filed: December 21, 2018
    Publication date: June 25, 2020
    Inventors: Drew Gross, Brian Pierce, Gillian Langor, Haven Lau
  • Publication number: 20200170665
    Abstract: An ultrasonic instrument includes a housing, an ultrasonic transducer support by the housing, and an integrated usage indicator. The housing is configured to removably connect to a shaft assembly. The ultrasonic transducer is configured to be acoustically connected to a waveguide and operated a predetermined number of use cycles. The integrated usage indicator is operatively connected to the housing and includes a used state indicator. The used state indicator is configured to indicate to a clinician in a used state when the ultrasonic transducer has been operated at least the predetermined number of use cycles for limiting usage of the ultrasonic transducer to the predetermined number of use cycles.
    Type: Application
    Filed: November 26, 2019
    Publication date: June 4, 2020
    Inventors: Ryan M. Asher, Brian D. Black, Chad P. Boudreaux, Nathan Cummings, William D. Dannaher, Craig T. Davis, Glenn W. Ellison, Frederick L. Estera, Jacob S. Gee, Geni Giannotti, Timothy S. Holland, Kevin L. Houser, Gregory W. Johnson, Amy M. Krumm, Jason R. Lesko, Stephen M. Leuck, Ion V. Nicolaescu, Candice Otrembiak, Amelia A. Pierce, Eric Roberson, Shan Wan
  • Patent number: 10628701
    Abstract: In general, certain embodiments of the present disclosure provide methods and systems for object detection by a neural network comprising a convolution-nonlinearity step and a recurrent step. In a training mode, a dataset is passed into the neural network, and the neural network is trained to accurately output a box size and a center location of an object of interest. The box size corresponds to the smallest possible bounding box around the object of interest and the center location corresponds to the location of the center of the bounding box. In an inference mode, an image that is not part of the dataset is passed into the neural network. The neural network automatically identifies an object of interest and draws a box around the identified object of interest. The box drawn around the identified object of interest corresponds to the smallest possible bounding box around the object of interest.
    Type: Grant
    Filed: September 10, 2018
    Date of Patent: April 21, 2020
    Assignee: Pilot AI Labs, Inc.
    Inventors: Brian Pierce, Elliot English, Ankit Kumar, Jonathan Su
  • Patent number: 10561436
    Abstract: An ultrasonic instrument includes a housing, an ultrasonic transducer support by the housing, and an integrated usage indicator. The housing is configured to removably connect to a shaft assembly. The ultrasonic transducer is configured to be acoustically connected to a waveguide and operated a predetermined number of use cycles. The integrated usage indicator is operatively connected to the housing and includes a used state indicator. The used state indicator is configured to indicate to a clinician in a used state when the ultrasonic transducer has been operated at least the predetermined number of use cycles for limiting usage of the ultrasonic transducer to the predetermined number of use cycles.
    Type: Grant
    Filed: July 31, 2017
    Date of Patent: February 18, 2020
    Assignee: Ethicon LLC
    Inventors: Ryan M. Asher, Brian D. Black, Chad P. Boudreaux, Nathan Cummings, William D. Dannaher, Craig T. Davis, Glenn W. Ellison, Frederick L. Estera, Jacob S. Gee, Geni Giannotti, Timothy S. Holland, Kevin L. Houser, Gregory W. Johnson, Amy M. Krumm, Jason R. Lesko, Stephen M. Leuck, Ion V. Nicolaescu, Candice Otrembiak, Amelia A. Pierce, Eric Roberson, Shan Wan
  • Publication number: 20200038409
    Abstract: A compound having the structure: or a pharmaceutically acceptable salt thereof, wherein X is N or CR, where R is hydrogen, deuterium, C1-C4 alkyl, C1-C4 alkoxy, C3-C6 cycloalkyl, aryl, heteroaryl, aryl(C1-C6 alkyl), CN, amino, alkylamino, dialkylamino, CF3, or hydroxyl; A is selected from the group consisting of a bond, C?O, —SO2—, —(C?O)NR0—, and —(CRaRb)q—, where R0 is H or C1-C4 alkyl, and Ra and Rb are independently hydrogen, deuterium, C1-C6 alkyl, C3-C6 cycloalkyl, aryl, aryl(C1-C6 alkyl), heteroaryl, (C1-C6 alkyl)heteroaryl, etc.
    Type: Application
    Filed: September 24, 2019
    Publication date: February 6, 2020
    Applicant: Pfizer Inc.
    Inventors: Andrew FENSOME, Ariamala GOPALSAMY, Brian S. GERSTENBERGER, Ivan Viktorovich EFREMOV, Zhao-Kui WAN, Betsy PIERCE, Jean-Baptiste TELLIEZ, John I. TRUJILLO, Liying ZHANG, Li XING, Eddine SAIAH
  • Patent number: 10526391
    Abstract: Molecular constructs and dual recognition constructs having a sequence encoding a TCR affinity weakening motif, and DNA and RNA sequences corresponding thereto, are presented. Modified T-cells and other cells transformed with the molecular contracts express a modified TCR that imparts a reduction, in non-specific binding, -an enhancement of binding specificity and an enhancement of binding affinity for a target antigen, compared to non-transformed (wild-type, native) T-cells, are described. The modified TCRs possess an affinity enhancing motif and an affinity weakening motif. Methods of transforming cells and methods of using enriched populations of transformed cells, in the treatment of cancer and infections arid T-cell mediated pathologies are provided. The affinity weakening motif imparts a weakened interaction, of a TCR with major histocompatibility complex proteins, such as HLA proteins in humans.
    Type: Grant
    Filed: July 22, 2015
    Date of Patent: January 7, 2020
    Assignees: The University of Notre Dame du Lac, University of Massachusetts
    Inventors: Brian Baker, Lance Hellman, Brian Pierce, Zhiping Weng
  • Publication number: 20190384751
    Abstract: Systems and methods for live reindexing include receiving, at a dispatch server, a request to reindex a database, wherein, at the time the request to reindex is received, the dispatch server is configured to send queries for information in the database to a first index server, the first index server comprising a first index of information in the database. The systems and methods further include, responsive to receiving the request to reindex and while the database is live, generating a second index of the information in the database, storing the second index at a second index server, and configuring the dispatch server to use the second index server as a live index server and to no longer use the first index server as a live index server.
    Type: Application
    Filed: August 30, 2019
    Publication date: December 19, 2019
    Inventors: Alan Pierce, Brian Dorne, Michael Glazer, Derek Rabideau, Richard Allen Ducott, III, David Karesh, Dylan Davis, Matthew Dailey, Hongyi Yao, Daniel Robinson
  • Patent number: 10463675
    Abstract: A compound having the structure: or an acceptable salt thereof, wherein X is N or CR, where R is hydrogen, alkyl, etc.; A is selected from the group consisting of a bond, C?O, —SO2—, etc.; A? is selected from the group consisting of a bond, C?O, etc.; Z is —(CH2)h— or a bond, etc.; R1 and R1? are independently selected from the group consisting of hydrogen, alkyl, etc.; R2 is selected from hydrogen, alkyl, etc.; R3 is selected from the group consisting of hydrogen, and amino; R4 is monocyclic or bicyclic, etc.; R5 is independently selected from hydrogen, alkyl, etc.; h, j, k, m, n and q are integers as defined in the specification. Also provided are methods of treatment as Janus Kinase inhibitors and pharmaceutical compositions containing the compounds of the invention and combinations with other therapeutic agents.
    Type: Grant
    Filed: May 3, 2017
    Date of Patent: November 5, 2019
    Assignee: Pfizer Inc.
    Inventors: Andrew Fensome, Ariamala Gopalsamy, Brian S. Gerstenberger, Ivan Viktorovich Efremov, Zhao-Kui Wan, Betsy Pierce, Jean-Baptiste Telliez, John I. Trujillo, Liying Zhang, Li Xing, Eddine Saiah
  • Patent number: 10402385
    Abstract: Systems and methods for live reindexing include receiving, at a dispatch server, a request to reindex a database, wherein, at the time the request to reindex is received, the dispatch server is configured to send queries for information in the database to a first index server, the first index server comprising a first index of information in the database. The systems and methods further include, responsive to receiving the request to reindex and while the database is live, generating a second index of the information in the database, storing the second index at a second index server, and configuring the dispatch server to use the second index server as a live index server and to no longer use the first index server as a live index server.
    Type: Grant
    Filed: August 27, 2015
    Date of Patent: September 3, 2019
    Assignee: Palantir Technologies Inc.
    Inventors: Alan Pierce, Brian Dorne, Michael Glazer, Derek Rabideau, Richard Allen Ducott, III, David Karesh, Dylan Davis, Matthew Dailey, Hongyi Yao, Daniel Robinson
  • Publication number: 20190019056
    Abstract: In general, certain embodiments of the present disclosure provide methods and systems for object detection by a neural network comprising a convolution-nonlinearity step and a recurrent step. In a training mode, a dataset is passed into the neural network, and the neural network is trained to accurately output a box size and a center location of an object of interest. The box size corresponds to the smallest possible bounding box around the object of interest and the center location corresponds to the location of the center of the bounding box. In an inference mode, an image that is not part of the dataset is passed into the neural network. The neural network automatically identifies an object of interest and draws a box around the identified object of interest. The box drawn around the identified object of interest corresponds to the smallest possible bounding box around the object of interest.
    Type: Application
    Filed: September 10, 2018
    Publication date: January 17, 2019
    Applicant: Pilot AI Labs, Inc.
    Inventors: Brian Pierce, Elliot English, Ankit Kumar, Jonathan Su
  • Patent number: 10078794
    Abstract: In general, certain embodiments of the present disclosure provide methods and systems for object detection by a neural network comprising a convolution-nonlinearity step and a recurrent step. In a training mode, a dataset is passed into the neural network, and the neural network is trained to accurately output a box size and a center location of an object of interest. The box size corresponds to the smallest possible bounding box around the object of interest and the center location corresponds to the location of the center of the bounding box. In an inference mode, an image that is not part of the dataset is passed into the neural network. The neural network automatically identifies an object of interest and draws a box around the identified object of interest. The box drawn around the identified object of interest corresponds to the smallest possible bounding box around the object of interest.
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: September 18, 2018
    Assignee: PILOT AI LABS, INC.
    Inventors: Brian Pierce, Elliot English, Ankit Kumar, Jonathan Su
  • Publication number: 20180209136
    Abstract: A multi-family building structure using prefabricated parallel modular living units is provided. The structure comprises at least first plurality of parallel modular living units and a second plurality of parallel modular living units. Each living unit in the first plurality of living units comprises a first outer and inner modules and a first synthetic residential module between the first outer module and the first inner module. Each living unit in the first plurality of living units comprises a second outer and outer modules and a second synthetic residential module between the second outer module and the second inner module. The structure further comprises a synthetic corridor module formed between the first inner module of the each living unit in the first plurality of living units and the second inner module in the second plurality of living units. The outer modules and the inner modules are devoid of redundant side walls.
    Type: Application
    Filed: January 24, 2018
    Publication date: July 26, 2018
    Inventors: Peter G. Aylward, Douglas J. McCarron, Daniel M. Odom, Brian Pierce, Patrick Flood
  • Publication number: 20170333524
    Abstract: Molecular constructs and dual recognition constructs having a sequence encoding a TCR affinity weakening motif, and DNA and RNA sequences corresponding thereto, are presented. Modified T-cells and other cells transformed with the molecular contracts express a modified TCR that imparts a reduction, in non-specific binding, an enhancement of binding specificity and an enhancement of binding affinity for a target antigen, compared to non-transformed (wild-type, native) T-cells, are described. The modified TCRs possess an affinity enhancing motif and an affinity weakening motif. Methods of transforming cells and methods of using enriched populations of transformed cells, in the treatment of cancer and infections arid T-cell mediated pathologies are provided. The affinity weakening motif imparts a weakened interaction, of a TCR with major histocompatibility complex proteins, such as HLA proteins in humans.
    Type: Application
    Filed: July 22, 2015
    Publication date: November 23, 2017
    Inventors: Brian BAKER, Lance HELLMAN, Brian PIERCE, Zhiping WENG
  • Publication number: 20170161592
    Abstract: According to various embodiments, a method for neural network dataset enhancement is provided. The method comprises taking a first picture using a fixed camera of just a set background, then taking a second picture with the fixed camera. The second picture is taken with the set background and an object of interest in the picture frame. The method further comprises extracting pixels of the image of the object of interest from the second picture, and superimposing the pixels of the image of the object of interest onto a plurality of different images.
    Type: Application
    Filed: December 5, 2016
    Publication date: June 8, 2017
    Applicant: Pilot AI Labs, Inc.
    Inventors: Jonathan Su, Ankit Kumar, Brian Pierce, Elliot English
  • Publication number: 20170161607
    Abstract: According to various embodiments, a method for gesture recognition using a neural network is provided. The method comprises a training mode and an inference mode. In the training mode, the method includes: passing a dataset into the neural network; and training the neural network to recognize a gesture of interest, wherein the neural network includes a convolution-nonlinearity step and a recurrent step. The inference mode, the method includes: passing a series of images into the neural network, wherein the series of images is not part of the dataset; and recognizing the gesture of interest in the series of images.
    Type: Application
    Filed: December 5, 2016
    Publication date: June 8, 2017
    Inventors: Elliot English, Ankit Kumar, Brian Pierce, Jonathan Su
  • Publication number: 20170160751
    Abstract: According to various embodiments, a method for controlling drone movement for object tracking is provided. The method comprises: receiving a position and a velocity of a target; receiving sensor input from a drone; determining an angular velocity and a linear velocity for the drone; and controlling movement of the drone to track the target using the determined angular velocity and linear velocity.
    Type: Application
    Filed: December 5, 2016
    Publication date: June 8, 2017
    Applicant: Pilot AI Labs, Inc.
    Inventors: Brian Pierce, Elliot English, Ankit Kumar, Jonathan Su
  • Publication number: 20170161591
    Abstract: According to various embodiments, a method for deep-learning based object tracking by a neural network is provided. The method comprises a training mode and an inference mode. In the training mode, the method includes: passing a dataset into the neural network, the dataset including a first image frame and a second image frame; and training the neural network to accurately output a similarity measure for the first and second image frames. In the inference mode, the method includes: passing a plurality of image frames into the neural network, wherein the plurality of image frames is not part of the dataset, the plurality of image frames comprising a first image frame and a second image frame, the first image frame including a first bounding box around an object and the second image frame including a second bounding box around an object; and automatically determining whether the object bounded by the first bounding box is the same object as the object bounded by the second bounding box.
    Type: Application
    Filed: December 2, 2016
    Publication date: June 8, 2017
    Applicant: Pilot AI Labs, Inc.
    Inventors: Elliot English, Ankit Kumar, Brian Pierce, Jonathan Su
  • Patent number: D857093
    Type: Grant
    Filed: January 23, 2019
    Date of Patent: August 20, 2019
    Assignee: CAPITAL ONE SERVICES, LLC
    Inventors: Brian R. Mills, Carl Pierce
  • Patent number: D866660
    Type: Grant
    Filed: February 15, 2019
    Date of Patent: November 12, 2019
    Assignee: CAPITAL ONE SERVICES, LLC
    Inventors: Brian R. Mills, Carl Pierce
  • Patent number: D868887
    Type: Grant
    Filed: May 24, 2019
    Date of Patent: December 3, 2019
    Assignee: CAPITAL ONE SERVICES, LLC
    Inventors: Brian R. Mills, Carl Pierce