Patents by Inventor Brian R. Fritz

Brian R. Fritz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polynucleotides containing a stabilizing tail region
    Patent number: 12109274
    Abstract: The invention features polynucleotides encoding a polypeptide including a 3?-stabilizing region and having increased stability compared to wild-type polynucleotides.
    Type: Grant
    Filed: September 19, 2016
    Date of Patent: October 8, 2024
    Assignee: ModernaTX, Inc.
    Inventors: Gabor Butora, Andrew W. Fraley, Edward John Miracco, Jennifer Nelson, Amy Rhoden Smith, Matthew Stanton, Brian R. Fritz
  • Methods for in vitro ribosome synthesis and evolution
    Patent number: 11136574
    Abstract: Disclosed are methods, components, compositions, and kits for preparing and identifying engineered E. coli ribosomes. The E. coli ribosomes may be prepared and identified under a set of defined conditions, such as in the presences of antibiotics, in order to obtain an engineered ribosome that is resistant to the antibiotic.
    Type: Grant
    Filed: October 7, 2019
    Date of Patent: October 5, 2021
    Assignee: Northwestern University
    Inventors: Michael Christopher Jewett, Brian R. Fritz
  • MULTIMERIC POLYNUCLEOTIDES AND USES THEREOF
    Publication number: 20210061843
    Abstract: Aspects of the disclosure relate to multimeric molecules and methods of producing the same. In some embodiments, the multimeric molecules comprise at least two nucleic acid molecules (e.g., mRNA molecules) joined by covalent bonds between non-coding regions.
    Type: Application
    Filed: January 18, 2019
    Publication date: March 4, 2021
    Inventor: Brian R. FRITZ
  • Methods for In Vitro Ribosome Synthesis and Evolution
    Publication number: 20200063122
    Abstract: Disclosed are methods, components, compositions, and kits for preparing and identifying engineered E. coli ribosomes. The E. coli ribosomes may be prepared and identified under a set of defined conditions, such as in the presences of antibiotics, in order to obtain an engineered ribosome that is resistant to the antibiotic.
    Type: Application
    Filed: October 7, 2019
    Publication date: February 27, 2020
    Inventors: Michael Christopher Jewett, Brian R. Fritz
  • Methods for in vitro ribosome synthesis and evolution
    Patent number: 10457932
    Abstract: Disclosed are methods, components, compositions, and kits for preparing and identifying engineered E. coli ribosomes. The E. coli ribosomes may be prepared and identified under a set of defined conditions, such as in the presences of antibiotics, in order to obtain an engineered ribosome that is resistant to the antibiotic.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: October 29, 2019
    Assignee: Northwestern University
    Inventors: Michael Christopher Jewett, Brian R. Fritz