Patents by Inventor Brian R. Sloat

Brian R. Sloat has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Precipitation resistant small molecule drug formulations
    Patent number: 11833157
    Abstract: Embodiments of the invention are directed to formulations that provide a solution to the problem of small molecule (e.g., diazepam) precipitation at the injection site when administered as a highly-concentrated formulation. In certain aspects the formulations include at least one surfactant in a non-aqueous formulation, which prevents small molecule precipitation and improves the bioavailability of the drug by enhancing absorption into the systemic circulation.
    Type: Grant
    Filed: May 13, 2021
    Date of Patent: December 5, 2023
    Assignee: Xeris Pharmaceuticals, Inc.
    Inventors: Steven J. Prestrelski, Michael A. Sandoval, Brian R. Sloat
  • COMPOSITIONS FOR SUPPLEMENTING PRODUCTS WITH THERAPEUTIC AGENTS AND METHODS OF USE THEREOF
    Publication number: 20230233466
    Abstract: Some embodiments pertain to nanoparticle-based compositions and their use in methods for the delivery of therapeutic ingredients to subjects. In some embodiments, the compositions are stable for prolonged periods of time and provide enhanced bioavailability.
    Type: Application
    Filed: June 15, 2021
    Publication date: July 27, 2023
    Inventors: Brian R. SLOAT, Michael A SANDOVAL
  • COMPOSITIONS FOR THE DELIVERY OF THERAPEUTIC AGENTS AND METHODS OF USE AND MAKING THEREOF
    Publication number: 20230210771
    Abstract: Some embodiments pertain to nanoparticle-based compositions and their use in methods for the delivery of therapeutic agents to subjects. In some embodiments, the compositions are stable for prolonged periods of time and provide enhanced bioavailability.
    Type: Application
    Filed: June 8, 2021
    Publication date: July 6, 2023
    Applicant: DISRUPTION LABS INC.
    Inventors: Brian R. SLOAT, Michael A SANDOVAL
  • COMPOSITIONS FOR THE DELIVERY OF THERAPEUTIC AGENTS AND METHODS OF USE AND MAKING THEREOF
    Publication number: 20220241217
    Abstract: Some embodiments pertain to nanoparticle-based compositions and their use in methods for the delivery of CBD to subjects. In some embodiments, the compositions are stable for prolonged periods of time and provide enhanced bioavailability.
    Type: Application
    Filed: January 6, 2022
    Publication date: August 4, 2022
    Inventors: Brian R. SLOAT, Michael A. SANDOVAL, Tyler B. WEST
  • PRECIPITATION RESISTANT SMALL MOLECULE DRUG FORMULATIONS
    Publication number: 20220096493
    Abstract: Embodiments of the invention are directed to formulations that provide a solution to the problem of small molecule (e.g., diazepam) precipitation at the injection site when administered as a highly-concentrated formulation. In certain aspects the formulations include at least one surfactant in a non-aqueous formulation, which prevents small molecule precipitation and improves the bioavailability of the drug by enhancing absorption into the systemic circulation.
    Type: Application
    Filed: May 13, 2021
    Publication date: March 31, 2022
    Inventors: Steven J. PRESTRELSKI, Michael A. SANDOVAL, Brian R. SLOAT
  • Compositions for the delivery of therapeutic agents and methods of use and making thereof
    Patent number: 11260033
    Abstract: Some embodiments pertain to nanoparticle-based compositions and their use in methods for the delivery of CBD to subjects. In some embodiments, the compositions are stable for prolonged periods of time and provide enhanced bioavailability.
    Type: Grant
    Filed: March 24, 2021
    Date of Patent: March 1, 2022
    Assignee: DISRUPTION LABS INC.
    Inventors: Brian R. Sloat, Michael A. Sandoval, Tyler B. West
  • COMPOSITIONS FOR THE DELIVERY OF THERAPEUTIC AGENTS AND METHODS OF USE AND MAKING THEREOF
    Publication number: 20210290562
    Abstract: Some embodiments pertain to nanoparticle-based compositions and their use in methods for the delivery of CBD to subjects. In some embodiments, the compositions are stable for prolonged periods of time and provide enhanced bioavailability.
    Type: Application
    Filed: December 9, 2019
    Publication date: September 23, 2021
    Inventors: Brian R. Sloat, Michael A. Sandoval, Tyler B. West
  • COMPOSITIONS FOR THE DELIVERY OF THERAPEUTIC AGENTS AND METHODS OF USE AND MAKING THEREOF
    Publication number: 20210251917
    Abstract: Some embodiments pertain to nanoparticle-based compositions and their use in methods for the delivery of CBD to subjects. In some embodiments, the compositions are stable for prolonged periods of time and provide enhanced bioavailability.
    Type: Application
    Filed: March 24, 2021
    Publication date: August 19, 2021
    Inventors: Brian R. Sloat, Michael A. Sandoval, Tyler B. West
  • Precipitation resistant small molecule drug formulations
    Patent number: 11020403
    Abstract: Embodiments of the invention are directed to formulations that provide a solution to the problem of small molecule (e.g., diazepam) precipitation at the injection site when administered as a highly-concentrated formulation. In certain aspects the formulations include at least one surfactant in a non-aqueous formulation, which prevents small molecule precipitation and improves the bioavailability of the drug by enhancing absorption into the systemic circulation.
    Type: Grant
    Filed: May 31, 2018
    Date of Patent: June 1, 2021
    Assignee: Xeris Pharmaceuticals, Inc.
    Inventors: Steven J. Prestrelski, Michael A. Sandoval, Brian R. Sloat
  • PRECIPITATION RESISTANT SMALL MOLECULE DRUG FORMULATIONS
    Publication number: 20180369255
    Abstract: Embodiments of the invention are directed to formulations that provide a solution to the problem of small molecule (e.g., diazepam) precipitation at the injection site when administered as a highly-concentrated formulation. In certain aspects the formulations include at least one surfactant in a non-aqueous formulation, which prevents small molecule precipitation and improves the bioavailability of the drug by enhancing absorption into the systemic circulation.
    Type: Application
    Filed: May 31, 2018
    Publication date: December 27, 2018
    Inventors: Steven J. PRESTRELSKI, Michael A. Sandoval, Brian R. Sloat