Patents by Inventor Brian R. Worth

Brian R. Worth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing tripdiolide, triptolide and celastrol
    Patent number: 4328309
    Abstract: A process for the production of tripdiolide, triptolide and celastrol comprises the steps of:(a) preparing a cellular inoculum from Tripterygium wilfordii Hook F;(b) inoculating a nutrient growth medium with the cellular inoculum and incubating the inoculated growth medium at 20.degree.-30.degree. C. for up to 8 weeks to produce a cellular product;(c) harvesting the cellular product from the inoculated growth medium; and(d) isolating tripdiolide, triptolide and celastrol from the cellular product and supernatant inoculated growth medium.
    Type: Grant
    Filed: July 2, 1980
    Date of Patent: May 4, 1982
    Assignee: The United States of America as represented by the Secretary of the Department of Health & Human Services
    Inventors: William T. Chalmers, James P. Kutney, Phillip J. Salisbury, Kenneth L. Stuart, Phillip M. Townsley, Brian R. Worth