Patents by Inventor Brian Reavy

Brian Reavy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODIFIED VIRD2 PROTEIN AND ITS USE IN IMPROVED GENE TRANSFER
    Publication number: 20100323397
    Abstract: There is provided a method for Agrobacterium-mediated gene transformation of a host cell. The method uses an Agrobacterium which expresses a VirD2 protein resistant to cleavage by a caspase. The VirD2 protein is modified by replacement of an aspartic acid residue with an alternative amino acid at one or more of the caspase cleavage sites within the protein amino acid sequence. This method improves the low efficiency of Agrobacterium-mediated gene transfer in certain plant cells and in animal cells caused by caspase cleavage of the VirD2 protein. The modified VirD2 protein, a gene for its expression and a method of producing a protein of interest by Agrobacterium-mediated transformation of a host cell are also described.
    Type: Application
    Filed: May 10, 2007
    Publication date: December 23, 2010
    Applicant: SCOTTISH CROP RESEARCH INSTITUTE
    Inventors: Brian Reavy, Mikhail Talianski, Sang Hyon Kim, Andrey Borisowich Vartapetian, Nina Valentinovna Chichkova, Svetlana Bagirova