Patents by Inventor Brian S. BERNSTEIN

Brian S. BERNSTEIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODIFIED ORTHOPOXVIRUS VECTORS
    Publication number: 20240132913
    Abstract: The disclosure relates to modified orthopoxvirus vectors, as well as methods of using the same for the treatment of various cancers. The disclosure provides modified orthopoxvirus vectors that exhibit various beneficial therapeutic activities, including enhanced oncolytic activity, spread of infection, immune evasion, tumor persistence, capacity for incorporation of exogenous DNA sequences and safety. The viruses we have discovered are also amenable to large scale manufacturing protocols.
    Type: Application
    Filed: September 4, 2023
    Publication date: April 25, 2024
    Applicants: OTTAWA HOSPITAL RESEARCH INSTITUTE, TURNSTONE BIOLOGICS CORP.
    Inventors: John C. Bell, Fabrice Le Boeuf, Michael S. Huh, Matthew Y. Tang, Adrian Pelin, Brian Andrew Keller, Caroline J. Breitbach, Michael F. Burgess, Steven H. Bernstein
  • SYSTEM, METHOD AND APPARATUS FOR ASSURING AUTHENTICITY AND PERMISSIBLE USE OF ELECTRONIC DOCUMENTS
    Publication number: 20090292930
    Abstract: A system and method for secure document management including tagging and/or remotely tracking documents exchanged between one or more users and a document repository. In some embodiments, the security policies for documents are determined based at least in part on document content, metadata associated with the document, and/or usage history of the document.
    Type: Application
    Filed: April 24, 2009
    Publication date: November 26, 2009
    Inventors: Robert F. MARANO, Brian S. BERNSTEIN, Ali RESUTOV