Patents by Inventor Brian S. Middleditch

Brian S. Middleditch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bioremediation of polar organic compounds
    Patent number: 5369031
    Abstract: The present invention provides an economical and efficient method for the elimination and biodegradation of soil and groundwater containing polar organic solvents, especially acetone. The bioremediation methods of the present invention comprise contacting the bacteria Xanthomonas maltophilia or Bacillus thuringiensis with the contaminated medium under appropriate conditions. In addition, the present invention provides for a composition of matter useful in the bioremediation of a medium, e.g., groundwater or soil contaminated with polar organic compounds, such as acetone.
    Type: Grant
    Filed: July 21, 1992
    Date of Patent: November 29, 1994
    Assignee: University of Houston
    Inventors: Brian S. Middleditch, Peter S. K. Lee
  • Cell growth inhibitors and methods of treating cancer and cell proliferative diseases
    Patent number: 5216024
    Abstract: The present invention discloses new and useful compounds including methyl p-hydroxyphenyllactate, its analogues, chemical derivatives and chemically related compounds and their use as antitumor agents, as inhibitors of proliferative cell growth and as prophylactic agents to inhibit and prevent cancer and non-malignant cell growth.
    Type: Grant
    Filed: July 15, 1988
    Date of Patent: June 1, 1993
    Assignee: Baylor College of Medicine
    Inventors: Barry M. Markaverich, James H. Clark, Rebecca Gregory, Mary Alejandro, Brian S. Middleditch, Gregory A. Johnson, Rajender S. Varma