Abstract: Systems and methods relating to improving the experience of gig-economy workers are disclosed, with particular reference to gig-economy work involving vehicle use. During or after performance of gig-economy work, data automatically collected may be used to generate and present recommendations or education points to gig-economy workers. Such recommendations may include targeted alerts to notify gig-economy workers of high-demand situations or to coordinate between gig-economy workers and gig-economy customers. Alerts may be generated based upon current excess demand for gig-economy services, as well as gig-economy worker availability and preferences. For example, alerts may be generated in response to detecting emergency conditions in an area in order to mobilize a large number of gig-economy transportation service providers.

Abstract: A welding-type power supply including a balanced plate rectifier to rectify high frequency alternating current from one or more transformers. The balanced plate rectifier includes an output terminal symmetrically connected to the plates of the plate rectifiers. The impedance between the output terminal and each plate is substantially equal.

Abstract: Welding power supplies, wire feeders, and systems to measure a weld cable voltage drop are disclosed. Example welding-type power supplies include a power converter configured to convert input power to output welding-type power to a remote device via a weld cable; a reference conductor connected between the power supply and the remote device; a voltage monitor configured to determine a first voltage between the weld cable and the reference conductor while substantially zero current is being conducted through the reference conductor; and a receiver circuit configured to receive a second voltage between the weld cable and the reference conductor from the remote device.

Abstract: Systems and methods to reduce magnetic flux in a switched mode power supply are disclosed. An example welding-type power supply includes a switched mode power supply, including a transformer configured to transform an input voltage to a welding-type voltage; switches configured to control a voltage applied to the primary winding of the transformer; a current detector configured to measure a current through the primary winding; a flux accumulator configured to determine a net flux in the transformer based on a number of volt-seconds applied to the primary winding of the transformer; and a controller configured to: control duty cycles of the switches based on the net flux; and set a value of the net flux in response to the current through the primary winding satisfying a current threshold.

Abstract: A lancet device includes a housing, a removable front cap mounted to the housing, a lancet holding member, a trigger and an arming system comprising a grippable cocking member structured and arranged to place the lancet device in a trigger-set or armed position. A depth adjustment system includes a member that is at least slidable and partially rotatably mounted and that has an axis of rotation arranged substantially parallel to a center axis of the lancet holding member. An ejection system includes an ejector having a portion extending outside a sidewall opening of the housing and being located closer to a front end of the housing than to a rear end of the housing. The sidewall opening of the housing is arranged on an area of the housing located between the trigger and a wall of the housing located opposite the trigger. The ejection system is structured and arranged to at least one of prevent axial movement of the lancet holding member or remove or eject a lancet from the lancet holding member.

Abstract: Systems and methods to estimate magnetic flux in a switched mode power supply are disclosed. An example welding-type power supply includes a switched mode power supply, comprising: a transformer configured to transform an input voltage to a welding-type voltage; a capacitor in series with a primary winding of the transformer; and switches configured to control a voltage applied to a series combination of the primary winding of the transformer and the capacitor; a voltage estimator coupled to the transformer and configured to output a signal representative of an alternating-current (AC)-coupled voltage at the capacitor; and a flux accumulator to determine a net flux in the transformer based on the voltage applied to the series combination of the primary winding of the transformer and the capacitor.

Abstract: The present invention provides methods and compositions for the treating a patient with a genetic disease, such as fibronectin glomerulopathy, hereditary coproporphyria and others. Methods and compositions are also provided for modulating the disease-associated gene(s) by altering gene signaling networks.

Abstract: The application relates to a compound of Formula (I): or a pharmaceutically acceptable salt thereof, tautomer, prodrug, solvate, metabolite, polymorph, analog or derivative thereof, which modulates the activity of BTK, a pharmaceutical composition comprising the compound of Formula (I), and a method of treating or preventing a disease in which BTK plays a role.

Abstract: The application relates to a compound of Formula (I): or a pharmaceutically acceptable salt thereof, tautomer, prodrug, solvate, metabolite, polymorph, analog or derivative thereof, which modulates the activity of BTK, a pharmaceutical composition comprising the compound of Formula (I), and a method of treating or preventing a disease in which BTK plays a role.

Abstract: Systems and techniques are provided for syncing shared resource across multiple systems using an intermediary system. The system includes logic to store membership data that includes a plurality of members in a membership. The system includes logic to create a reference content hash for the shared resource of the membership. The system can download the content hash of a copy of shared resource, upon receiving a notification of a transaction with the copy of the shared resource. The system can compare the content hash of the copy with the content hash of the master copy to detect any changes to the copy of shared resource. The system can designate the copy of shared resource with updated content as master copy and fanout the master copy to storage accounts associated with members in the membership. The system can perform the fanout for sets of members in the membership.

Abstract: The application relates to a compound of Formula (I): or a pharmaceutically acceptable salt thereof, tautomer, prodrug, solvate, metabolite, polymorph, analog or derivative thereof, which modulates the activity of BTK, a pharmaceutical composition comprising the compound of Formula (I), and a method of treating or preventing a disease in which BTK plays a role.

Abstract: A welding-type power supply including a balanced plate rectifier to rectify high frequency alternating current from one or more transformers. The balanced plate rectifier includes an output terminal symmetrically connected to the plates of the plate rectifiers. The impedance between the output terminal and each plate is substantially equal.

Abstract: The present application is drawn to methods of treating a cell proliferative disorder, such as a cancer, comprising administering to a subject in need thereof a therapeutically effective amount of a composition comprising at least one of Compound 1, Compound 2, and Compound 3, or a pharmaceutically acceptable salt, solvate, hydrate, or prodrug thereof, and at least one second therapeutic agent or a pharmaceutically acceptable salt, solvate, hydrate, or prodrug thereof, wherein the cell proliferative disorder is treated.

Abstract: The application relates to a compound of Formula (I): or a pharmaceutically acceptable salt thereof, tautomer, prodrug, solvate, metabolite, polymorph, analog or derivative thereof, which modulates the activity of BTK, a pharmaceutical composition comprising the compound of Formula (I), and a method of treating or preventing a disease in which BTK plays a role.

Abstract: A method and apparatus for providing welding-type power supply includes a power circuit and a controller. The power circuit receives input power and provides welding type power and auxiliary power. It is controlled on a control input. The power circuit also includes an auxiliary power transformer. A temperature responsive component is mounted in the auxiliary power transformer and provides a temperature signal indicative of the temperature in the auxiliary power transformer. The controller controls a cooling fan for the aux power transformer and/or turns off the aux power output in response to the sensed temperature.

Abstract: A method and apparatus for providing welding type power, including a power and control circuit is disclosed. The power circuit provides welding, control and aux power. The control and aux power are provided with a transformer, and secondary windings for control and aux power are wound on a single bobbin, with a winding separator separating them. Air vents, which can be formed by fins on the bobbin or separator allow cooling of the inner winding.

Abstract: A method and apparatus for providing welding-type power supply includes a power circuit and a controller. The power circuit receives input power and provides welding type power and auxiliary power. It is controlled on a control input. The power circuit also includes an auxiliary power transformer. A temperature responsive component is mounted in the auxiliary power transformer and provides a temperature signal indicative of the temperature in the auxiliary power transformer. The controller controls a cooling fan for the aux power transformer and/or turns off the aux power output in response to the sensed temperature.

Abstract: The application relates to a compound of Formula (I): or a pharmaceutically acceptable salt thereof, tautomer, prodrug, solvate, metabolite, polymorph, analog or derivative thereof, which modulates the activity of BTK, a pharmaceutical composition comprising the compound of Formula (I), and a method of treating or preventing a disease in which BTK plays a role.

Abstract: A new and distinct cultivar of Bermudagrass hybrid Cynodon transvaalensis x Cynodon dactylon named ‘12-TG-101’ is provided. The new and distinct upright variety is characterized by a combination of superior turfgrass uniformity, very dark green leaf color, and high putting green speeds. The asexually reproduced triploid variety is reliably propagated vegetatively.

Abstract: A new and distinct cultivar of Centipedegrass named ‘Tift TC458’ is provided. The new and distinct variety has excellent turf quality, increased seed head production, and increased nematode resistance as compared to similar commercial centipedegrass. The sexually and asexually reproduced diploid variety is reliably propagated both vegetatively and by seed.