Patents by Inventor Brian Shuch

Brian Shuch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11311538
    Abstract: In various aspects and embodiments the invention provides a method of treating or preventing a cancer in a mammalian subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of at least one compound selected from the group consisting of a DNA repair inhibitor, a DNA strand break repair inhibitor, and a homologous recombination (HR) repair inhibitor, wherein cells in the cancer comprise a fumarate hydratase (FH) and/or succinate dehydrogenase (SDH) mutation.
    Type: Grant
    Filed: July 12, 2019
    Date of Patent: April 26, 2022
    Assignee: YALE UNIVERSITY
    Inventors: Ranjit Bindra, Peter Glazer, Parker Sulkowski, Brian Shuch
  • Publication number: 20200016156
    Abstract: In various aspects and embodiments the invention provides a method of treating or preventing a cancer in a mammalian subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of at least one compound selected from the group consisting of a DNA repair inhibitor, a DNA strand break repair inhibitor, and a homologous recombination (HR) repair inhibitor, wherein cells in the cancer comprise a fumarate hydratase (FH) and/or succinate dehydrogenase (SDH) mutation.
    Type: Application
    Filed: July 12, 2019
    Publication date: January 16, 2020
    Inventors: Ranjit Bindra, Peter Glazer, Parker Sulkowski, Brian Shuch