Abstract: The disclosure provides methods for treating or limiting development age-related macular degeneration, comprising (a) a GPR143 receptor agonist, including but not limited to L-DOPA, L-DOPA analogues, or a pharmaceutically acceptable salt thereof, and (b) melatonin, a melatonin analogue, or a pharmaceutically acceptable salt thereof, and related compositions.

Abstract: The invention provides antibodies, and antigen-binding fragments thereof, that specifically bind to CXCR5. The antibodies can be afucosylated and exhibit increased ADCC compared with the otherwise identical fucosylated antibodies. The invention includes uses, and associated methods of using the antibodies.

Abstract: According to one aspect, a method includes obtaining a sensor assembly that includes at least a first camera and a second camera, and positioning the sensor assembly in an enclosure of a sensor testing system. The enclosure has a first enclosure target and a second enclosure target affixed thereon, and includes a sensor arrangement. The sensor testing assembly further includes a computing arrangement and a data acquisition arrangement, The method also includes performing a first test on the sensor assembly by providing commands to the sensor assembly using the computing arrangement, and monitoring the sensor assembly during the first test. Monitoring the sensor assembly includes obtaining data from the sensor assembly and/or the sensor arrangement, and providing the data to the data acquisition arrangement. Finally, the method includes processing the data, wherein processing the data includes determining whether the data indicates that the sensor assembly passes the first test.

Abstract: A proppant container facilitates the transportation of wet sand for use in a hydraulic fracturing operation. The container is mounted in a cradle that tips downward in arcuate motion for discharge or proppant through a top opening The tipping mechanism may be driven by a system of gears or a hydraulic ram.

Abstract: Various methods and apparatus for dynamic stabilization of bones, and especially of vertebra. Disclosed herein are bushings that permit axial movement of a rod, tether, or similar interconnection device relative to an anchoring head that is coupled to a bone. Some bushings further allow lateral relative movement or rotational relative movement, such additional relative movement being limited by the size and shape of the bushing, the size and shape of the interconnection device, the size and shape of the bushing container, the manner of attaching the anchoring head to the bone, or other considerations.

Abstract: Athletic activity may be tracked while providing encouragement to perform athletic activity. For example, a user's route may be captured during a workout and used to assemble a media presentation corresponding to the workout. Prior captured images may be assembled forming a hyperlapse video and included in a media presentation corresponding to a user's workout. Images representing locations along a workout route may be assembled and provided in the media presentation and may be shared with other users.

Abstract: Athletic activity may be tracked while providing encouragement to perform athletic activity. For example, a user's route may be captured during a workout and used to assemble a media presentation corresponding to the workout. Prior captured images may be assembled forming a hyperlapse video and included in a media presentation corresponding to a user's workout. Images representing locations along a workout route may be assembled and provided in the media presentation and may be shared with other users.

Abstract: The invention provides antibodies, and antigen-binding fragments thereof, that specifically bind to CXCR5. The antibodies can be afucosylated and exhibit increased ADCC compared with the otherwise identical fucosylated antibodies. The invention includes uses, and associated methods of using the antibodies.

Abstract: The invention provides antibodies, and antigen-binding fragments thereof, that specifically bind to CXCR5. The antibodies can be afucosylated and exhibit increased ADCC compared with the otherwise identical fucosylated antibodies. The invention includes uses, and associated methods of using the antibodies.

Abstract: Embodiments disclosed herein include systems for the treatment of spinal deformity in children by harnessing growth modulation without requiring vertebral fusion. In some embodiments, the system uses flexible or moveable elements to selectively apply and tune forces and moments to the spine instead of rigid fixation and vertebral segment fusion.

Abstract: Embodiments disclosed herein include systems for the treatment of spinal deformity in children by harnessing growth modulation without requiring vertebral fusion. In some embodiments, the system uses flexible or moveable elements to selectively apply and tune forces and moments to the spine instead of rigid fixation and vertebral segment fusion.

Abstract: The invention provides antibodies, and antigen-binding fragments thereof, that specifically bind to CXCR5. The antibodies can be afucosylated and exhibit increased ADCC compared with the otherwise identical fucosylated antibodies. The invention includes uses, and associated methods of using the antibodies.

Abstract: Athletic activity may be tracked while providing encouragement to perform athletic activity. For example, a user's route may be captured during a workout and used to assemble a media presentation corresponding to the workout. Prior captured images may be assembled forming a hyperlapse video and included in a media presentation corresponding to a user's workout. Images representing locations along a workout route may be assembled and provided in the media presentation and may be shared with other users.

Abstract: Health and usage monitoring systems for aircraft hoist systems are described herein. In some embodiments, a health and usage monitoring system comprises a capacitive load cell and a processing unit for communication with the capacitive load cell, the capacitive load cell comprising a load receiving surface and a capacitive assembly coupled to the load receiving surface, the capacitive assembly comprising parallel electrically conductive plates separated by a reversibly deformable spacer construction wherein the parallel plates comprise aligned apertures providing a passageway through the capacitive assembly for the hoist system cable.

Abstract: A computerized appointment confirmation system for communication with a mobile device comprising a database comprising data regarding an appointment and a server configured to communicate with an MMS server, the MMS server configured to send an MMS message to the mobile device and receive an MMS response message, receive a communication from the MMS server indicating receipt of the MMS response message by the MMS server, communicate with an SMS server if no MMS response message is received from the mobile device within a predetermined time period, the SMS server configured to send an SMS message to the mobile device and receive an SMS response message, update the database to indicate whether confirmation data was received by the MMS or SMS server from the mobile device, and store in the database data indicating whether an MMS response message or SMS response message was received by the mobile device.

Abstract: Health and usage monitoring systems for aircraft hoist systems are described herein. In some embodiments, a health and usage monitoring system comprises a capacitive load cell and a processing unit for communication with the capacitive load cell, the capacitive load cell comprising a load receiving surface and a capacitive assembly coupled to the load receiving surface, the capacitive assembly comprising parallel electrically conductive plates separated by a reversibly deformable spacer construction wherein the parallel plates comprise aligned apertures providing a passageway through the capacitive assembly for the hoist system cable.

Abstract: An interactive, multi-media presentation viewing system and process for viewing educational or business presentations integrating presentation graphics in the form of presentation slides, video, audio, text, and other streaming media into a powerfully coordinated viewing experience for the end user. The viewing system is an aggregate of synchronized presentation graphics, video, and text displays employing a graphical user interface that allows the user to control all aspects of media playback.

Abstract: An interactive, multi-media presentation viewing system and process for viewing educational or business presentations integrating presentation graphics in the form of presentation slides, video, audio, text, and other streaming media into a powerfully coordinated viewing experience for the end user. The viewing system is an aggregate of synchronized presentation graphics, video, and text displays employing a graphical user interface that allows the user to control all aspects of media playback.

Abstract: A spinal fixation system having a modular construction to allow universal application to varying spine anatomy and load requirements of individual vertebral attachment members, while reducing requirements for large inventories to optimize spinal fixation. Modularity allows the individual attachment members, once attached optimally to bone, to be attached to a variety of interconnecting structural members optimized for load carrying capacity.

Abstract: An interactive, multi-media presentation viewing system and process for viewing educational or business presentations integrating presentation graphics in the form of presentation slides, video, audio, text, and other streaming media into a powerfully coordinated viewing experience for the end user. The viewing system is an aggregate of synchronized presentation graphics, video, and text displays employing a graphical user interface that allows the user to control all aspects of media playback.