Patents by Inventor Brian Stephen Sproat

Brian Stephen Sproat has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oligonucleotides containing high concentrations of guanine monomers
    Patent number: 9914746
    Abstract: This invention pertains to methods for oligonucleotide synthesis, specifically the synthesis of oligonucleotides that contain a high content of guanine monomers. In more detail, the invention relates to a method for coupling a nucleoside phosphoramidite during the synthesis of an oligonucleotide to a universal support, to a first nucleoside, or to an extending oligonucleotide. The invention further relates to oligonucleotides obtainable by the methods of the invention.
    Type: Grant
    Filed: June 23, 2015
    Date of Patent: March 13, 2018
    Assignee: KUROS BIOSCIENCES AG
    Inventor: Brian Stephen Sproat
  • OLIGONUCLEOTIDES CONTAINING HIGH CONCENTRATIONS OF GUANINE MONOMERS
    Publication number: 20160145293
    Abstract: This invention pertains to methods for oligonucleotide synthesis, specifically the synthesis of oligonucleotides that contain a high content of guanine monomers. In more detail, the invention relates to a method for coupling a nucleoside phosphoramidite during the synthesis of an oligonucleotide to a universal support, to a first nucleoside, or to an extending oligonucleotide. The invention further relates to oligonucleotides obtainable by the methods of the invention.
    Type: Application
    Filed: June 23, 2015
    Publication date: May 26, 2016
    Inventor: Brian Stephen Sproat
  • OLIGONUCLEOTIDES CONTAINING HIGH CONCENTRATIONS OF GUANINE MONOMERS
    Publication number: 20140200338
    Abstract: This invention pertains to methods for oligonucleotide synthesis, specifically the synthesis of oligonucleotides that contain a high content of guanine monomers. In more detail, the invention relates to a method for coupling a nucleoside phosphoramidite during the synthesis of an oligonucleotide to a universal support, to a first nucleoside, or to an extending oligonucleotide. The invention further relates to oligonucleotides obtainable by the methods of the invention.
    Type: Application
    Filed: October 15, 2013
    Publication date: July 17, 2014
    Applicant: CYTOS BIOTECHNOLOGY AG
    Inventor: BRIAN STEPHEN SPROAT
  • Oligonucleotides containing high concentrations of guanine monomers
    Patent number: 8586728
    Abstract: This invention pertains to methods for oligonucleotide synthesis, specifically the synthesis of oligonucleotides that contain a high content of guanine monomers. In more detail, the invention relates to a method for coupling a nucleoside phosphoramidite during the synthesis of an oligonucleotide to a universal support, to a first nucleoside, or to an extending oligonucleotide. The invention further relates to oligonucleotides obtainable by the methods of the invention.
    Type: Grant
    Filed: December 12, 2007
    Date of Patent: November 19, 2013
    Assignee: Cytos Biotechnology AG
    Inventor: Brian Stephen Sproat
  • COMPOUNDS
    Publication number: 20090054362
    Abstract: The present invention provides novel aptamer derivatives which are useful in binding to and neutralising viruses. Pharmaceutical formulations comprising the aptamers and the use of the aptamers in screening for useful compounds are also provided.
    Type: Application
    Filed: February 15, 2006
    Publication date: February 26, 2009
    Applicant: ISIS INNOVATION LIMITED
    Inventors: William James, Brian Stephen Sproat
  • OLIGONUCLEOTIDES CONTAINING HIGH CONCENTRATIONS OF GUANINE MONOMERS
    Publication number: 20080139797
    Abstract: This invention pertains to methods for oligonucleotide synthesis, specifically the synthesis of oligonucleotides that contain a high content of guanine monomers. In more detail, the invention relates to a method for coupling a nucleoside phosphoramidite during the synthesis of an oligonucleotide to a universal support, to a first nucleoside, or to an extending oligonucleotide. The invention further relates to oligonucleotides obtainable by the methods of the invention.
    Type: Application
    Filed: December 12, 2007
    Publication date: June 12, 2008
    Applicant: INTEGRATED DNA TECHNOLOGIES, INC.
    Inventor: Brian Stephen Sproat