Patents by Inventor Brian T. Chamberlain

Brian T. Chamberlain has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS RELATED TO BICYCLO[2.2.1] HEPTANAMINE-CONTAINING COMPOUNDS
    Publication number: 20240116850
    Abstract: The present disclosure relates to compositions and methods related to bicyclo[2.2.1]heptanamine-containing compounds and salts thereof.
    Type: Application
    Filed: December 23, 2021
    Publication date: April 11, 2024
    Inventors: Brian T. Chamberlain, Florence F. Wagner, Maria Alimova, Anna Greka
  • Compositions and methods related to di-substituted bicyclo[2.2.1] heptanamine-containing compounds
    Patent number: 11840495
    Abstract: The present disclosure relates to compositions and methods related to bicyclo[2.2.1] heptanamine-containing compounds and salts.
    Type: Grant
    Filed: December 23, 2021
    Date of Patent: December 12, 2023
    Assignees: The Broad Institute, Inc., Instituto Carlos Slim de la Salud, A.C., Brigham and Women's Hospital, Inc.
    Inventors: Brian T. Chamberlain, David Kornfilt, Florence F. Wagner, Maria Alimova, Anna Greka, Joseph Growney
  • OXOACRIDINYL ACETIC ACID DERIVATIVES AND METHODS OF USE
    Publication number: 20230113570
    Abstract: Compounds of Formula I or pharmaceutically acceptable salts or esters thereof capable of binding to and modulating the activity of a stimulator of interferon genes (STING) protein are provided. Methods involving compounds of Formula I as effective modulators of STING are also provided.
    Type: Application
    Filed: July 28, 2022
    Publication date: April 13, 2023
    Inventors: Brian T. CHAMBERLAIN, James M. RICE, Finith E. JERNIGAN, III, Woody SHERMAN, Meghana M. KULKARNI, Sharon SHECHTER, Bryce K. ALLEN, Dazhi TAN, Kristen A. MARINO, Zhixiong LIN
  • Oxoacridinyl acetic acid derivatives and methods of use
    Patent number: 11414387
    Abstract: Compounds of Formula I or pharmaceutically acceptable salts or esters thereof capable of binding to and modulating the activity of a stimulator of interferon genes (STING) protein are provided. Methods involving compounds of Formula I as effective modulators of STING are also provided.
    Type: Grant
    Filed: July 8, 2020
    Date of Patent: August 16, 2022
    Assignee: STINGTHERA, INC.
    Inventors: Brian T. Chamberlain, James M. Rice, Finith E. Jernigan, III, Woody Sherman, Meghana M. Kulkarni, Sharon Shechter, Bryce K. Allen, Dazhi Tan, Kristen A. Marino, Zhixiong Lin
  • BENZO[B][1,8]NAPHTHYRIDINE ACETIC ACID DERIVATIVES AND METHODS OF USE
    Publication number: 20220251079
    Abstract: Compounds of Formula I or pharmaceutically acceptable salts or esters thereof capable of binding to and modulating the activity of a stimulator of interferon genes (STING) protein are provided. Methods involving compounds of Formula I as effective modulators of STING are also provided.
    Type: Application
    Filed: May 15, 2020
    Publication date: August 11, 2022
    Inventors: Bryce K. ALLEN, Brian T. CHAMBERLAIN, Timothy A. DWIGHT, Huang HUANG, Meghana M. KULKARNI, Zhixiong LIN, Kristen A. MARINO, Deqiang NIU, Sharon SHECHTER, Steven SWANN
  • COMPOSITIONS AND METHODS RELATED TO DI-SUBSTITUTED BICYCLO[2.2.1] HEPTANAMINE-CONTAINING COMPOUNDS
    Publication number: 20220242815
    Abstract: The present disclosure relates to compositions and methods related to bicyclo[2.2.1] heptanamine-containing compounds and salts.
    Type: Application
    Filed: December 23, 2021
    Publication date: August 4, 2022
    Inventors: Brian T. Chamberlain, David Kornfilt, Florence F. Wagner, Maria Alimova, Anna Greka, Joseph Growney
  • OXOACRIDINYL ACETIC ACID DERIVATIVES AND METHODS OF USE
    Publication number: 20220227761
    Abstract: Compounds of Formulae I, II, their pharmaceutically acceptable salts or esters thereof capable of binding to and modulating the activity of a stimulator of interferon genes (STING) protein are provided. Methods involving compounds of Formulae I or II as effective modulators of STING are also provided.
    Type: Application
    Filed: May 15, 2020
    Publication date: July 21, 2022
    Inventors: Bryce K. ALLEN, Brian T. CHAMBERLAIN, Timothy A. DWIGHT, Huang HUANG, Zhixiong LIN, Kristen A. MARINO, Deqiang NIU, Sharon SHECHTER, Steven SWANN
  • OXOACRIDINYL ACETIC ACID DERIVATIVES AND METHODS OF USE
    Publication number: 20210002230
    Abstract: Compounds of Formula I or pharmaceutically acceptable salts or esters thereof capable of binding to and modulating the activity of a stimulator of interferon genes (STING) protein are provided. Methods involving compounds of Formula I as effective modulators of STING are also provided.
    Type: Application
    Filed: July 8, 2020
    Publication date: January 7, 2021
    Inventors: Brian T. CHAMBERLAIN, James M. RICE, Finith E. JERNIGAN, III, Woody SHERMAN, Meghana M. KULKARNI, Sharon SHECHTER, Bryce K. ALLEN, Dazhi TAN, Kristen A. MARINO, Zhixiong LIN
  • Oxoacridinyl acetic acid derivatives and methods of use
    Patent number: 10745358
    Abstract: Compounds of Formula I or pharmaceutically acceptable salts or esters thereof capable of binding to and modulating the activity of a stimulator of interferon genes (STING) protein are provided. Methods involving compounds of Formula I as effective modulators of STING are also provided.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: August 18, 2020
    Assignee: Silicon SWAT, Inc.
    Inventors: Brian T. Chamberlain, James M. Rice, Finith E. Jernigan, III, Woody Sherman, Meghana M. Kulkarni, Sharon Shechter, Bryce K. Allen, Dazhi Tan, Kristen A. Marino, Zhixiong Lin
  • Protective molecules against anthrax toxin
    Patent number: 10730848
    Abstract: Disclosed herein inter alia are compositions and methods useful in the treatment of infectious diseases and exposure to toxins.
    Type: Grant
    Filed: July 16, 2015
    Date of Patent: August 4, 2020
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Eugene Gillespie, Robert Damoiseaux, Chi-Lee Charlie Ho, Brian T. Chamberlain, Michael E. Jung, Kenneth A. Bradley
  • Bone-selective osteogenic oxysterol bisphosphonate analogs
    Patent number: 10421773
    Abstract: Oxysterol-bisphosphonate and oxysterol-alendronic acid compounds, compositions including them, and methods using them for the treatment of bone disorders.
    Type: Grant
    Filed: May 1, 2015
    Date of Patent: September 24, 2019
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Farhad Parhami, Frank Stappenbeck, Brian T. Chamberlain
  • OXOACRIDINYL ACETIC ACID DERIVATIVES AND METHODS OF USE
    Publication number: 20190161449
    Abstract: Compounds of Formula I or pharmaceutically acceptable salts or esters thereof capable of binding to and modulating the activity of a stimulator of interferon genes (STING) protein are provided. Methods involving compounds of Formula I as effective modulators of STING are also provided.
    Type: Application
    Filed: November 20, 2018
    Publication date: May 30, 2019
    Inventors: Brian T. CHAMBERLAIN, James M. RICE, Finith E. JERNIGAN, III, Woody SHERMAN, Meghana M. KULKARNI, Sharon SHECHTER, Bryce K. ALLEN, Dazhi TAN, Kristen A. MARINO, Zhixiong LIN
  • BONE-SELECTIVE OSTEOGENIC OXYSTEROL BISPHOSPHONATE ANALOGS
    Publication number: 20170022244
    Abstract: Oxysterol-bisphosphonate and oxysterol-alendronic acid compounds, compositions including them, and methods using them for the treatment of bone disorders.
    Type: Application
    Filed: May 1, 2015
    Publication date: January 26, 2017
    Inventors: Farhad Parhami, Frank Stappenbeck, Brian T. Chamberlain
  • PROTECTIVE MOLECULES AGAINST ANTHRAX TOXIN
    Publication number: 20160016930
    Abstract: Disclosed herein inter alia are compositions and methods useful in the treatment of infectious diseases and exposure to toxins.
    Type: Application
    Filed: July 16, 2015
    Publication date: January 21, 2016
    Inventors: Eugene Gillespie, Robert Damoiseaux, Chi-Lee Charlie Ho, Brian T. Chamberlain, Michael E. Jung, Kenneth A. Bradley