Patents by Inventor Brian T. Phillips

Brian T. Phillips has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4-cycloakylaminopyrazolo pyrimidine NMDA/NR2B antagonists
    Patent number: 7452893
    Abstract: Compounds represented by Formula (I) or pharmaceutically acceptable salts thereof, are effective as NMDA/NR2B antagonists useful for treating neurological conditions such as, for example, pain, Parkinson's disease, Alzheimer's disease, epilepsy, depression, anxiety, ischemic brain injury including stroke, and other conditions.
    Type: Grant
    Filed: August 11, 2004
    Date of Patent: November 18, 2008
    Assignee: Merck & Co., Inc.
    Inventors: Wayne Thompson, Steven D. Young, Brian T. Phillips, Peter Munson, Willie Whitter, Nigel Liverton, Christine Dieckhaus, John Butcher, John A. McCauley, Charles J. McIntyre, Mark E. Layton, Philip E. Sanderson
  • Thrombin inhibitors
    Patent number: 5872138
    Abstract: A compound which inhibits human thrombin and which has the general structure ##STR1##
    Type: Grant
    Filed: September 10, 1997
    Date of Patent: February 16, 1999
    Assignee: Merck & Co., Inc.
    Inventors: Adel M. Naylor-Olsen, Gerald S. Ponticello, Joseph P. Vacca, Randall W. Hungate, Craig Coburn, Brian T. Phillips, S. D. Lewis, Mark E. Fraley
  • Fused polycyclic and bridged compounds useful as calcium channel blockers
    Patent number: 4808718
    Abstract: Novel fused polycyclic and bridged compounds are disclosed which are useful as calcium entry blockers.
    Type: Grant
    Filed: May 6, 1986
    Date of Patent: February 28, 1989
    Assignee: Merck & Co., Inc.
    Inventors: George D. Hartman, Wasyl Halczenko, Brian T. Phillips
  • Certain 1,4-dihydro-2,6-di-lower hydrocarbyl-4-heterocyclic-3,5-pyridine dicarboxylates which are useful as calcium channel blockers
    Patent number: 4735956
    Abstract: Novel substituted 4-heteroaryl-1,4-dihydropyridine compounds useful as calcium channel blockers, pharmaceutical compositions therof, and methods of treatment are disclosed.
    Type: Grant
    Filed: September 13, 1985
    Date of Patent: April 5, 1988
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, Wasyl Halczenko, George D. Hartman, Brian T. Phillips
  • Cyclized N-substituted-tetrahydropyridine compounds and cardiovascular use
    Patent number: 4721708
    Abstract: Novel N-substituted tetrahydropyridine compounds are disclosed. The compounds have the property of inhibiting calcium induced contraction of smooth muscle and are adaptable to being employed in the chemotherapeutic treatment of cardiovascular diseases.
    Type: Grant
    Filed: November 26, 1985
    Date of Patent: January 26, 1988
    Assignee: Merck & Co., Inc.
    Inventors: George D. Hartman, Brian T. Phillips
  • Benzo(f)isoquinoline compounds useful as calcium entry blockers
    Patent number: 4670443
    Abstract: Benzo(f)isoquinoline compounds, particularly, penta- and tetrahydrobenzo(f)isoquinoline dicarboxylic acid compounds, their preparation and their use as calcium entry blockers are disclosed.
    Type: Grant
    Filed: July 2, 1985
    Date of Patent: June 2, 1987
    Assignee: Merck & Co., Inc.
    Inventors: George D. Hartman, Brian T. Phillips
  • Substituted and bridged pyridines useful as calcium channel blockers
    Patent number: 4532237
    Abstract: Novel substituted and bridged pyridine compounds useful as calcium channel blockers, pharmaceutical compositions thereof, and methods of treatment are disclosed.
    Type: Grant
    Filed: July 30, 1984
    Date of Patent: July 30, 1985
    Assignee: Merck & Co., Inc.
    Inventors: George D. Hartman, Brian T. Phillips