Patents by Inventor Brian Varnum

Brian Varnum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • WEAPON ANTI-CANT INDICATOR
    Publication number: 20240077282
    Abstract: An anti-cant indicator assembly, components thereof, and associated methods. The anti-cant indicator assembly indicates the orientation of a weapon with respect to vertical. The anti-cant indicator assembly includes a mount configured to mount to the weapon, a level including a vial containing a bubble and a pivot connection connecting the level to the mount. The pivot connection is configured to permit movement of the level with respect to the mount about the pivot connection between an operational position in which the bubble can be referenced by the user for indicating orientation of the weapon with respect to vertical, and a stowed position different from the operational position. The pivot connection can include a retainer configured to releasably retain the level in at least one of the operational position or the stowed position. The level can be selectively movable with respect to the mount to calibrate the anti-cant indicator.
    Type: Application
    Filed: November 10, 2023
    Publication date: March 7, 2024
    Applicant: AOB Products Company
    Inventors: Mike Lindsay, Michael Cottrell, James Tayon, Timothy S. Kinney, Mark Dalton, Brian Steere, Justin Burke, Kyle Martin, Dennis W. Cauley, JR., Anthony Vesich, Ryan Varnum, Seth Wheeler, Brett Eckelkamp, Matthew Kinamore, Curtis Smith
  • Therapeutic human anti-IL-1R1 monoclonal antibody
    Patent number: 9534053
    Abstract: Antibodies that interact with interleukin-1 receptor type 1 (IL-1R1) are described. Methods of treating IL-1 mediated diseases by administering a pharmaceutically effective amount of antibodies to IL-1R1 are described. Methods of detecting the amount of IL-1R1 in a sample using antibodies to IL-1R1 are described.
    Type: Grant
    Filed: March 5, 2014
    Date of Patent: January 3, 2017
    Assignees: Amgen Inc., E.R. Squibb & Sons, L.L.C.
    Inventors: Brian Varnum, Chris Vezina, Alison Witte, Xueming Qian, Francis Hall Martin, Haichun Huang, Gary Elliott
  • THERAPEUTIC HUMAN ANTI-IL-1R1 MONOCLONAL ANTIBODY
    Publication number: 20140335099
    Abstract: Antibodies that interact with interleukin-1 receptor type 1 (IL-1R1) are described. Methods of treating IL-1 mediated diseases by administering a pharmaceutically effective amount of antibodies to IL-1R1 are described. Methods of detecting the amount of IL-1R1 in a sample using antibodies to IL-1R1 are described.
    Type: Application
    Filed: March 5, 2014
    Publication date: November 13, 2014
    Applicants: Amgen Inc., Medarex, L.L.C.
    Inventors: Brian Varnum, Chris Vezina, Alison Witte, Xueming Qian, Francis Hall Martin, Haichun Huang, Gary Elliott
  • Therapeutic human anti-IL-1R1 monoclonal antibody
    Patent number: 8710203
    Abstract: Antibodies that interact with interleukin-1 receptor type 1 (IL-1R1) are described. Methods of treating IL-1 mediated diseases by administering a pharmaceutically effective amount of antibodies to IL-1R1 are described. Methods of detecting the amount of IL-1R1 in a sample using antibodies to IL-1R1 are described.
    Type: Grant
    Filed: August 7, 2013
    Date of Patent: April 29, 2014
    Assignees: Amgen Inc., Medarex, L.L.C.
    Inventors: Brian Varnum, Chris Vezina, Alison Witte, Xueming Qian, Francis Hall Martin, Haichun Huang, Gary Elliot
  • THERAPEUTIC HUMAN ANTI-IL-1R1 MONOCLONAL ANTIBODY
    Publication number: 20140039164
    Abstract: Antibodies that interact with interleukin-1 receptor type 1 (IL-1R1) are described. Methods of treating IL-1 mediated diseases by administering a pharmaceutically effective amount of antibodies to IL-1R1 are described. Methods of detecting the amount of IL-1R1 in a sample using antibodies to IL-1R1 are described.
    Type: Application
    Filed: August 7, 2013
    Publication date: February 6, 2014
    Applicants: Medarex, Inc., Amgen Inc.
    Inventors: Brian Varnum, Chris Vezina, Alison Witte, Xueming Qian, Francis Hall Martin, Haichun Huang, Gary Elliott
  • Therapeutic human anti-IL-1R1 monoclonal antibody
    Patent number: 8518407
    Abstract: Antibodies that interact with interleukin-1 receptor type 1 (IL-1R1) are described. Methods of treating IL-1 mediated diseases by administering a pharmaceutically effective amount of antibodies to IL-1R1 are described. Methods of detecting the amount of IL-1R1 in a sample using antibodies to IL-1R1 are described.
    Type: Grant
    Filed: April 18, 2012
    Date of Patent: August 27, 2013
    Assignees: Amgen Inc., Medarex, Inc.
    Inventors: Brian Varnum, Chris Vezina, Alison Witte, Xueming Qian, Francis Hall Martin, Haichun Huang, Gary Elliott
  • THERAPEUTIC HUMAN ANTI-IL-1R1 MONOCLONAL ANTIBODY
    Publication number: 20120269824
    Abstract: Antibodies that interact with interleukin-1 receptor type 1 (IL-1R1) are described. Methods of treating IL-1 mediated diseases by administering a pharmaceutically effective amount of antibodies to IL-1R1 are described. Methods of detecting the amount of IL-1R1 in a sample using antibodies to IL-1R1 are described.
    Type: Application
    Filed: April 18, 2012
    Publication date: October 25, 2012
    Applicants: Medarex, Inc., Amgen Inc.
    Inventors: Brian Varnum, Chris Vezina, Alison Witte, Xueming Qian, Francis Hall Martin, Haichun Huang, Gary Elliott
  • Therapeutic human anti-IL-1R1 monoclonal antibody
    Patent number: 8236559
    Abstract: Antibodies that interact with interleukin-1 receptor type 1 (IL-1R1) are described. Methods of treating IL-1 mediated diseases by administering a pharmaceutically effective amount of antibodies to IL-1R1 are described. Methods of detecting the amount of IL-1R1 in a sample using antibodies to IL-1R1 are described.
    Type: Grant
    Filed: September 15, 2008
    Date of Patent: August 7, 2012
    Assignees: Medarex, Inc., Amgen Inc.
    Inventors: Brian Varnum, Chris Vezina, Alison Witte, Xueming Qian, Francis Hall Martin, Haichun Huang, Gary Elliott
  • Therapeutic Human Anti-IL-1R1 Monoclonal Antibody
    Publication number: 20090214559
    Abstract: Antibodies that interact with interleukin-1 receptor type 1 (IL-1R1) are described. Methods of treating IL-1 mediated diseases by administering a pharmaceutically effective amount of antibodies to IL-1R1 are described. Methods of detecting the amount of IL-1R1 in a sample using antibodies to IL-1R1 are described.
    Type: Application
    Filed: September 15, 2008
    Publication date: August 27, 2009
    Applicants: AMGEN, INC., MEDAREX INC.
    Inventors: Brian Varnum, Chris Vezina, Alison Witte, Xueming Qian, Francis Hall Martin, Haichun Huang, Gary Elliott
  • Therapeutic human anti-IL1-R1 monoclonal antibody
    Patent number: 7438910
    Abstract: Antibodies that interact with interleukin-1 receptor type 1 (IL-1R1) are described. Methods of treating IL-1 mediated diseases by administering a pharmaceutically effective amount of antibodies to IL-1R1 are described. Methods of detecting the amount of IL-1R1 in a sample using antibodies to IL-1R1 are described.
    Type: Grant
    Filed: September 5, 2003
    Date of Patent: October 21, 2008
    Assignees: Amgen Inc., Medarex, Inc.
    Inventors: Brian Varnum, Chris Vezina, Alison Witte, Xueming Qian, Francis Hall Martin, Haichun Huang, Gary Elliott
  • Screening method for antibodies and other selective IL-1 binding agents that allow binding to IL-1 receptor but not activation thereof
    Publication number: 20050084493
    Abstract: The invention concerns methods of treating IL-1-mediated disease by administering a selective IL-1 binding agents that form an antagonist complex with the IL-1 ligand. The antagonist complex can bind to the IL-1 receptor without activating the receptor. The selective binding agents contemplated by this invention thus have the properties of free ligand absorption (through binding of the selective binding agent to free IL-1? or ?) and receptor activation inhibition (through binding of the antagonist complex to the receptor and preventing its activation).
    Type: Application
    Filed: November 9, 2004
    Publication date: April 21, 2005
    Inventors: Alison Witte, Brian Varnum, Xueming Qian, Chris Vezina
  • Therapeutic human anti-IL1-R1 monoclonal antibody
    Publication number: 20040097712
    Abstract: Antibodies that interact with interleukin-1 receptor type 1 (IL-1R1) are described. Methods of treating IL-1 mediated diseases by administering a pharmaceutically effective amount of antibodies to IL-1R1 are described. Methods of detecting the amount of IL-1R1 in a sample using antibodies to IL-1R1 are described.
    Type: Application
    Filed: September 5, 2003
    Publication date: May 20, 2004
    Applicant: Amgen, Inc. A Corporation of the State of Delaware
    Inventors: Brian Varnum, Chris Vezina, Alison Witte, Xueming Qian, Francis Hall Martin, Haichun Huang, Gary Elliott