Patents by Inventor Brian W. Ward

Brian W. Ward has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tracer Reagents that Enhance Reaction-Product Analysis
    Publication number: 20080160518
    Abstract: A composition suitable for formulation of an enzymatic reaction mixture, the composition comprising a reaction component essential for an ex-vivo non-polymerase enzymatic reaction in which a substrate is catalyzed by an enzyme in a reaction mixture to form a product, and a tracer compatible with the enzyme, the composition being substantially free of the substrate.
    Type: Application
    Filed: April 12, 2007
    Publication date: July 3, 2008
    Applicant: SIGMA ALDRICH CO.
    Inventors: Brian W. Ward, David M. Ornitz, Michael G. Deines, Thomas F. Bittick
  • STABILIZED COMPOSITIONS OF THERMOSTABLE DNA POLYMERASE AND ANIONIC OR ZWITTERIONIC DETERGENT
    Publication number: 20080145910
    Abstract: The present invention provides compositions, methods, and kits for protecting thermostable DNA polymerase during amplification reactions conducted at a temperature ranging from about 40° C. to greater than 100° C. The composition comprises a thermostable DNA polymerase and an anionic detergent or zwitterionic detergent.
    Type: Application
    Filed: December 19, 2006
    Publication date: June 19, 2008
    Applicant: SIGMA ALDRICH COMPANY
    Inventors: Brian W. Ward, Ernest J. Mueller, Jessica Copeland, Deborah Vassar
  • Methods and Compositions for Amplification of DNA
    Publication number: 20080124768
    Abstract: Compositions for the amplification of damaged nucleic acids are disclosed. The compositions generally comprise a mesophilc polymerase, a thermostable polymerase, and an AP endonuclease. Methods of using the same for the amplification of damaged DNA are also disclosed.
    Type: Application
    Filed: October 31, 2006
    Publication date: May 29, 2008
    Applicant: Sigma Aldrich Co.
    Inventors: Ernest J. Mueller, Kevin J. Kayser, Brian W. Ward, Christopher Walker, Erik Eastlund, Jason Milligan
  • Tracer reagents that enhance reaction-product analysis
    Patent number: 7169584
    Abstract: A composition suitable for formulation of an enzymatic reaction mixture, the composition comprising a reaction component essential for an ex-vivo non-polymerase enzymatic reaction in which a substrate is catalyzed by an enzyme in a reaction mixture to form a product, and a tracer compatible with the enzyme, the composition being substantially free of the substrate.
    Type: Grant
    Filed: February 15, 2005
    Date of Patent: January 30, 2007
    Assignee: Sigma-Aldrich Co.
    Inventors: Brian W. Ward, David M. Ornitz, Michael R. Deines, Thomas F. Bittick
  • Tracer reagents that enhance reaction-product analysis
    Patent number: 6942964
    Abstract: A composition suitable for formulation of an enzymatic reaction mixture, the composition comprising a reaction component essential for an ex-vivo non-polymerase enzymatic reaction in which a substrate is catalyzed by an enzyme in a reaction mixture to form a product, and a tracer compatible with the enzyme, the composition being substantially free of the substrate.
    Type: Grant
    Filed: July 6, 2000
    Date of Patent: September 13, 2005
    Assignee: Sigma-Aldrich Co.
    Inventors: Brian W. Ward, David M. Ornitz, Michael G. Deines, Thomas F. Bittick