Patents by Inventor Brian Wainger

Brian Wainger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods to treat neurodegenerative diseases
    Patent number: 10195173
    Abstract: The specification provides compositions and methods to treat neurodegenerative diseases.
    Type: Grant
    Filed: November 8, 2016
    Date of Patent: February 5, 2019
    Assignees: Children's Medical Center Corporation, The General Hospital Corporation, President and Fellows of Harvard College
    Inventors: Clifford J. Woolf, Brian Wainger, Evangelos Kiskinis, Kevin Eggan
  • METHODS TO TREAT NEURODEGENERATIVE DISEASES
    Publication number: 20170273930
    Abstract: The specification provides compositions and methods to treat neurodegenerative diseases.
    Type: Application
    Filed: November 8, 2016
    Publication date: September 28, 2017
    Inventors: Clifford J. Woolf, Brian Wainger, Evangelos Kiskinis, Kevin Eggan
  • Methods to treat neurodegenerative diseases
    Patent number: 9517223
    Abstract: The present invention is based on the discovery that motor neurons derived from patients with a neurodegenerative disease have decreased delayed rectifier potassium current and increased persistent sodium current compared to motor neurons derived from control healthy individuals. The present invention is also based on the discovery that the class of compounds known as “potassium channel openers” can be used to treat neurodegenerative diseases, including ALS, Parkinson's disease, Alzheimer's disease, epilepsy, and pain.
    Type: Grant
    Filed: August 6, 2013
    Date of Patent: December 13, 2016
    Assignees: The General Hospital Corporation, Children's Medical Center Corporation, President and Fellows of Harvard College
    Inventors: Clifford J. Woolf, Brian Wainger, Evangelos Kiskinis, Kevin Eggan
  • METHODS TO TREAT NEURODEGENERATIVE DISEASES
    Publication number: 20150190363
    Abstract: The present invention is based on the discovery that motor neurons derived from patients with a neuro-degenerative disease have decreased delayed rectifier potassium current and increased persistent sodium current compared to motor neurons derived from control healthy individuals. The present invention is also based on the discovery that the class of compounds known as “potassium channel openers” can be used to treat neurodegenerative diseases, including ALS, Parkinson's disease, Alzheimer's disease, epilepsy, and pain.
    Type: Application
    Filed: August 6, 2013
    Publication date: July 9, 2015
    Applicant: Children's Medical Center Corporation
    Inventors: Clifford J. Woolf, Brian Wainger, Evangelos Kiskinis, Kevin Eggan